Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Rosemeire M Kanashiro-Takeuchi"'
Autor:
Sana Nasim, Popular Pandey, Rosemeire M. Kanashiro-Takeuchi, Jin He, Joshua D. Hutcheson, Lidia Kos
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The aortic valve (AoV) maintains unidirectional blood distribution from the left ventricle of the heart to the aorta for systemic circulation. The AoV leaflets rely on a precise extracellular matrix microarchitecture of collagen, elastin, and proteog
Externí odkaz:
https://doaj.org/article/3e6c0e773a5e4f4fa180d13c587470a9
Autor:
Rosemeire M. Kanashiro-Takeuchi, Katarzyna Kazmierczak, Jingsheng Liang, Lauro M. Takeuchi, Yoel H. Sitbon, Danuta Szczesna-Cordary
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15589 (2022)
In this study, we aimed to investigate whether short-term and low-dose treatment with hydroxychloroquine (HCQ), an antimalarial drug, can modulate heart function in a preclinical model of dilated cardiomyopathy (DCM) expressing the D94A mutation in c
Externí odkaz:
https://doaj.org/article/132cbd8fcfcb4b07b75aa5ebbca1b30e
Autor:
Raul A Dulce, Rosemeire M Kanashiro-Takeuchi, Lauro M Takeuchi, Alessandro G Salerno, Amarylis C B A Wanschel, Shathiyah Kulandavelu, Wayne Balkan, Marilia S S R Zuttion, Renzhi Cai, Andrew V Schally, Joshua M Hare
Publikováno v:
Cardiovascular Research. 118:3586-3601
Aims To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signalling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart fail
Autor:
Rosemeire M. Kanashiro-Takeuchi, Lauro M. Takeuchi, Raul A. Dulce, Katarzyna Kazmierczak, Wayne Balkan, Renzhi Cai, Wei Sha, Andrew V. Schally, Joshua M. Hare
Heart failure (HF) with preserved ejection fraction (HFpEF) represents a major unmet medical need owing to its diverse pathophysiology and lack of effective therapies. Potent synthetic, agonists (MR-356 and MR409) of growth hormone-releasing hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5eb5724af07ef228e142b868993d34
https://doi.org/10.1101/2022.09.18.508429
https://doi.org/10.1101/2022.09.18.508429
Autor:
Michael A. Bellio, Shathiyah Kulandavelu, Wayne Balkan, Karen C. Young, Lauro M Takeuchi, Yee-Shuan Lee, Rosemeire M. Kanashiro-Takeuchi, Aisha Khan, Joshua M. Hare
Publikováno v:
The journal of cardiovascular aging
Introduction: Cardiovascular disease and myocardial infarction are leading causes of morbidity and mortality in aged populations. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are under evaluation as a therapeutic option for the tr
Autor:
Raul A, Dulce, Rosemeire M, Kanashiro-Takeuchi, Lauro M, Takeuchi, Alessandro G, Salerno, Amarylis C B A, Wanschel, Shathiyah, Kulandavelu, Wayne, Balkan, Marilia S S R, Zuttion, Renzhi, Cai, Andrew V, Schally, Joshua M, Hare
Publikováno v:
Cardiovasc Res
To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signaling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart failure wi
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Cell Transplantation
Cell Transplantation
Progenitor/stem cell-based kidney regenerative strategies are a key step towards the development of novel therapeutic regimens for kidney disease treatment. However, the route of cell delivery, e.g., intravenous, intra-arterial, or intra-parenchymal,
Autor:
Rosemeire M. Kanashiro-Takeuchi, Alessandro Salerno, Andrew V. Schally, Amarylis C. B. A. Wanschel, Peter Buchwald, Joshua M. Hare, Ivonne Hernandez Schulman, Raul A Dulce, Victoria Florea, Marcos Rosado, Darren Turner, Luiza Bagno, Wayne Balkan, Angela C. Rieger, Jose Rodriguez, Lauro M Takeuchi
Publikováno v:
Proc Natl Acad Sci U S A
Therapies for heart failure with preserved ejection fraction (HFpEF) are lacking. Growth hormone-releasing hormone agonists (GHRH-As) have salutary effects in ischemic and nonischemic heart failure animal models. Accordingly, we hypothesized that GHR
Autor:
Lauro M Takeuchi, Rosemeire M. Kanashiro-Takeuchi, Raul A Dulce, Renzhi Cai, Andrew V. Schally, Joshua M. Hare, Wayne Balkan, Alessandro Salerno
Publikováno v:
Circulation. 142
Introduction: Heart failure with preserved ejection fraction (HFpEF) accounts for ~50% of heart failure cases and is characterized by impaired relaxation, ventricular stiffening and fibrosis. Growth hormone releasing hormone-agonists (GHRH-As) reduce
Autor:
Sunil Batlahally, Andrew Franklin, Pingping Chen, Shathiyah Kulandavelu, Karen C. Young, Rosemeire M. Kanashiro-Takeuchi, Karen K. Mestan, Augusto F. Schmidt, Eliana C. Martinez, Divya Keerthy, Lina A. Shehadeh, Andreas Damianos, Michael Freundlich, Jian Huang, Mayank Sharma, Merline Benny, Marissa DeFreitas, Ronald Zambrano, Joanne Duara, Shu Wu, Carolyn Abitbol
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Preterm infants with bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) have accelerated lung aging and poor long-term outcomes. Klotho is an antiaging protein that modulates oxidative stress, angiogenesis and fibrosis. Here we test the