Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rosemary Oh"'
Autor:
Aaron B Bogutz, Rosemary Oh-McGinnis, Karen J Jacob, Rita Ho-Lau, Ting Gu, Marina Gertsenstein, Andras Nagy, Louis Lefebvre
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007587 (2018)
The basic helix-loop-helix (bHLH) transcription factor ASCL2 plays essential roles in diploid multipotent trophoblast progenitors, intestinal stem cells, follicular T-helper cells, as well as during epidermal development and myogenesis. During early
Externí odkaz:
https://doaj.org/article/4b8c1397f9204a85a379358372ebd388
Autor:
Andras Nagy, Ting Gu, Marina Gertsenstein, Louis Lefebvre, Rita Ho-Lau, Aaron B. Bogutz, K. J. Jacob, Rosemary Oh-McGinnis
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 8, p e1007587 (2018)
PLoS Genetics, Vol 14, Iss 8, p e1007587 (2018)
The basic helix-loop-helix (bHLH) transcription factor ASCL2 plays essential roles in diploid multipotent trophoblast progenitors, intestinal stem cells, follicular T-helper cells, as well as during epidermal development and myogenesis. During early
Publikováno v:
HAPS Educator. 20:73-80
Publikováno v:
Briefings in Functional Genomics. 9:281-293
The development of gene targeting approaches has had a tremendous impact on the functional analysis of the mouse genome. A specific application of this technique has been the adaptation of the bacteriophage P1 Cre/loxP site-specific recombinase syste
Autor:
Lynn Mar, John Hsien, Jana Paderova, Rita Ho, Louis Lefebvre, Marina Gertsenstein, Jeremy A. Squire, Andras Nagy, Rosemary Oh, Michael J. Higgins
Publikováno v:
Molecular and Cellular Biology. 28:1092-1103
The distal end of mouse chromosome 7 (Chr 7) contains a large cluster of imprinted genes. In this region two cis-acting imprinting centers, IC1 (H19 DMR) and IC2 (KvDMR1), define proximal and distal subdomains, respectively. To assess the functional
Autor:
Yu Tian Wang, Michael R. Hayden, Andras Nagy, Martina Metzler, Claire-Anne Gutekunst, Marina Gertsenstein, Rosemary Oh, Bo Li, John C. Roder, Peter S. McPherson, Lu Gan, Christine M. Alvarez, Yushan Wang, Valerie Legendre-Guillemin, Mark M. Rich, John Georgiou, Enrique Torre, Rebecca S. Devon, Lynn A. Raymond
Publikováno v:
ResearcherID
Huntingtin interacting protein 1 (HIP1) is a recently identified component of clathrin-coated vesicles that plays a role in clathrin-mediated endocytosis. To explore the normal function of HIP1 in vivo, we created mice with targeted mutation in the H
Autor:
Elizabeth M. Simpson, Yu Deng, Michael R. Hayden, Rona K. Graham, Elizabeth J. Slow, Sazzad M. Hossain, Daniel A. Rogers, Nagat Bissada, Sarah H. Coleman, Rosemary Oh, Claire-Anne Gutekunst, Jeremy M. Van Raamsdonk, Yu-Zhou Yang, Blair R. Leavitt, Xiao-Jiang Li
Publikováno v:
Human Molecular Genetics. 12:1555-1567
An expanded CAG repeat is the underlying genetic defect in Huntington disease, a disorder characterized by motor, psychiatric and cognitive deficits and striatal atrophy associated with neuronal loss. An accurate animal model of this disease is cruci
Publikováno v:
BMC Developmental Biology, Vol 10, Iss 1, p 50 (2010)
BMC Developmental Biology
BMC Developmental Biology
Background Several imprinted genes have been implicated in the process of placentation. The distal region of mouse chromosome 7 (Chr 7) contains at least ten imprinted genes, several of which are expressed from the maternal homologue in the placenta.
Autor:
Lynn Mar, Jeremy A. Squire, Jana Paderova, Aaron B. Bogutz, Louis Lefebvre, Marina Gertsenstein, Mohammad A. Mandegar, Andras Nagy, Rosemary Oh-McGinnis
Publikováno v:
Human molecular genetics. 18(22)
Imprinted genes are commonly clustered in domains across the mammalian genome, suggesting a degree of coregulation via long-range coordination of their monoallelic transcription. The distal end of mouse chromosome 7 (Chr 7) contains two clusters of i