Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rosemary Kiernan"'
Autor:
Xavier Contreras, David Depierre, Charbel Akkawi, Marina Srbic, Marion Helsmoortel, Maguelone Nogaret, Matthieu LeHars, Kader Salifou, Alexandre Heurteau, Olivier Cuvier, Rosemary Kiernan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Pervasive transcription of the human genome generates an abundance of RNAs that must be processed and degraded. The nuclear RNA exosome is the main RNA degradation machinery in the nucleus. However, nuclear exosome must be recruited to its s
Externí odkaz:
https://doaj.org/article/dead10e00ef946ad9aa32b08b538a230
Autor:
Giuseppa Grasso, Charbel Akkawi, Celine Franckhauser, Rima Nait-Saidi, Maxime Bello, Jérôme Barbier, Rosemary Kiernan
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Nuclear factor 90 (NF90) is a double-stranded RNA-binding protein involved in a multitude of different cellular mechanisms such as transcription, translation, viral infection, and mRNA stability. Recent data suggest that NF90 migh
Externí odkaz:
https://doaj.org/article/8750de79e87d45ddbb3dc2b2ea7d6bd0
Autor:
Giuseppa Grasso, Rosemary Kiernan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13584 (2022)
Double-stranded RNA-binding proteins (dsRBPs) are major players in the regulation of gene expression patterns. Among them, Nuclear Factor 90 (NF90) has a plethora of well-known functions in viral infection, transcription, and translation as well as R
Externí odkaz:
https://doaj.org/article/0caf5073790948b2bc9603c0f2c8df39
Autor:
Xavier Contreras, Kader Salifou, Gabriel Sanchez, Marion Helsmoortel, Emmanuelle Beyne, Lisa Bluy, Stéphane Pelletier, Emilie Rousset, Sylvie Rouquier, Rosemary Kiernan
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006950 (2018)
Expression from the HIV-1 LTR can be repressed in a small population of cells, which contributes to the latent reservoir. The factors mediating this repression have not been clearly elucidated. We have identified a network of nuclear RNA surveillance
Externí odkaz:
https://doaj.org/article/408ec278d3734468aa37e065087d9fc1
Publikováno v:
Electrophoresis Letters. 65:13-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5396ca48b36727a7f06130c3c0b8e17d
https://doi.org/10.2198/electroph.65.13
https://doi.org/10.2198/electroph.65.13
Autor:
Shuji Sakamoto, Victor Mac, Claudio Lorenzi, Rosemary Kiernan, Jérôme Barbier, William Ritchie, Takuma Higuchi, Giuseppa Grasso, Maxime Bello, Marion Helsmoortel, Gabriel Sanchez
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2020, 48 (12), pp.6874-6888. ⟨10.1093/nar/gkaa386⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (12), pp.6874-6888. ⟨10.1093/nar/gkaa386⟩
MicroRNAs (miRNAs) are predicted to regulate the expression of >60% of mammalian genes and play fundamental roles in most biological processes. Deregulation of miRNA expression is a hallmark of most cancers and further investigation of mechanisms con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9d1c120636569ae4c1aae0101b17fe
http://europepmc.org/articles/PMC7337520
http://europepmc.org/articles/PMC7337520
Autor:
Kalina Timcheva, Solenne Dufour, Leila Touat-Todeschini, Callum Burnard, Marie-Christine Carpentier, Florent Chuffart, Rémy Merret, Marion Helsmoortel, Sabrina Ferré, Aude Grézy, Yohann Couté, Sophie Rousseaux, Saadi Khochbin, Claire Vourc’h, Cécile Bousquet-Antonelli, Rosemary Kiernan, Daphné Seigneurin-Berny, André Verdel
Publikováno v:
Cell Reports
Cell Reports, 2022, 41 (11), pp.111784. ⟨10.1016/j.celrep.2022.111784⟩
Cell Reports, 2022, 41 (11), pp.111784. ⟨10.1016/j.celrep.2022.111784⟩
Heat stress (HS) induces a cellular response leading to profound changes in gene expression. Here, we show that human YTHDC1, a reader of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990d0e2b6e7ebd27fcb4e035791d8ad4
https://doi.org/10.1016/j.celrep.2022.111784
https://doi.org/10.1016/j.celrep.2022.111784
Autor:
Giuseppa Grasso, Charbel Akkawi, Celine Franckhauser, Rima Nait-Saidi, Maxime Bello, Jérôme Barbier, Rosemary Kiernan
Background Nuclear factor 90 (NF90) is a double-stranded RNA-binding protein involved in a multitude of different cellular mechanisms such as transcription, translation, viral infection, and mRNA stability. Recent data suggest that NF90 might influen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9898ddda9bfb601fd6d998e6e43a5bd0
https://doi.org/10.1101/2021.09.23.461467
https://doi.org/10.1101/2021.09.23.461467
The conserved Polymerase-Associated Factor 1 complex (PAF1C) regulates all stages of the RNA polymerase II (RNAPII) transcription cycle from the promoter to the 3’ end formation site of mRNA encoding genes and has been linked to numerous transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f3ca0466cc2438cae706b89e56cc82
https://hal.archives-ouvertes.fr/hal-02989632
https://hal.archives-ouvertes.fr/hal-02989632
Autor:
Celine Franckhauser, Poornima Basavarajaiah, Olivier Cuvier, Rosemary Kiernan, Victor Mac, Emmanuelle Beyne, Marion Helsmoortel, David Depierre, Jérôme Déjardin, Callum Burnard, Giuseppa Grasso, Sylvie Rouquier, Xavier Contreras, Kader Salifou
Publikováno v:
Science Advances
Chromatin-associated MRN protects highly transcribing genes from genomic instability.
MRN-MDC1 plays a central role in the DNA damage response (DDR) and repair. Using proteomics of isolated chromatin fragments, we identified DDR factors, such as
MRN-MDC1 plays a central role in the DNA damage response (DDR) and repair. Using proteomics of isolated chromatin fragments, we identified DDR factors, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155859723d2783f5349c8c2acb3d001f
https://doi.org/10.1101/2020.05.27.118638
https://doi.org/10.1101/2020.05.27.118638