Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry

Autor: Natasha Bertelsen, Isotta Landi, Richard A. I. Bethlehem, Jakob Seidlitz, Elena Maria Busuoli, Veronica Mandelli, Eleonora Satta, Stavros Trakoshis, Bonnie Auyeung, Prantik Kundu, Eva Loth, Guillaume Dumas, Sarah Baumeister, Christian F. Beckmann, Sven Bölte, Thomas Bourgeron, Tony Charman, Sarah Durston, Christine Ecker, Rosemary J. Holt, Mark H. Johnson, Emily J. H. Jones, Luke Mason, Andreas Meyer-Lindenberg, Carolin Moessnang, Marianne Oldehinkel, Antonio M. Persico, Julian Tillmann, Steve C. R. Williams, Will Spooren, Declan G. M. Murphy, Jan K. Buitelaar, the EU-AIMS LEAP group, Simon Baron-Cohen, Meng-Chuan Lai, Michael V. Lombardo

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)

Natasha Bertelsen et al. develop a computational model to categorize patients with autism spectrum disorder (ASD) into distinct subgroups, based on social-communicative or restricted repetitive behaviors. By integrating publicly available neuroimagin

Externí odkaz: https://doaj.org/article/c94c4da54e7f411495da1401f7a3c862

The Link Between Autism and Sex-Related Neuroanatomy, and Associated Cognition and Gene Expression

Autor: Dorothea L, Floris, Han, Peng, Varun, Warrier, Michael V, Lombardo, Charlotte M, Pretzsch, Clara, Moreau, Alex, Tsompanidis, Weikang, Gong, Maarten, Mennes, Alberto, Llera, Daan, van Rooij, Marianne, Oldehinkel, Natalie J, Forde, Tony, Charman, Julian, Tillmann, Tobias, Banaschewski, Carolin, Moessnang, Sarah, Durston, Rosemary J, Holt, Christine, Ecker, Flavio, Dell'Acqua, Eva, Loth, Thomas, Bourgeron, Declan G M, Murphy, Andre F, Marquand, Meng-Chuan, Lai, Jan K, Buitelaar, Simon, Baron-Cohen, Christian F, Beckmann

Publikováno v: American Journal of Psychiatry, 180, 50-64
American Journal of Psychiatry, 180, 1, pp. 50-64
The American Journal of Psychiatry
The American Journal of Psychiatry, 2023, 180 (1), pp.50-64. ⟨10.1176/appi.ajp.20220194⟩

Item does not contain fulltext OBJECTIVE: The male preponderance in prevalence of autism is among the most pronounced sex ratios across neurodevelopmental conditions. The authors sought to elucidate the relationship between autism and typical sex-dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb4a20e77c2090765078ca0309e9e2d
https://doi.org/10.1176/appi.ajp.20220194

The EU-AIMS Longitudinal European Autism Project (LEAP): clinical characterisation

Autor: Tony Charman, Eva Loth, Julian Tillmann, Daisy Crawley, Caroline Wooldridge, David Goyard, Jumana Ahmad, Bonnie Auyeung, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Sven Bölte, Thomas Bourgeron, Carsten Bours, Michael Brammer, Daniel Brandeis, Claudia Brogna, Yvette de Bruijn, Bhismadev Chakrabarti, Ineke Cornelissen, Flavio Dell’ Acqua, Guillaume Dumas, Sarah Durston, Christine Ecker, Jessica Faulkner, Vincent Frouin, Pilar Garcés, Lindsay Ham, Hannah Hayward, Joerg Hipp, Rosemary J. Holt, Johan Isaksson, Mark H. Johnson, Emily J. H. Jones, Prantik Kundu, Meng-Chuan Lai, Xavier Liogier D’ardhuy, Michael V. Lombardo, David J Lythgoe, René Mandl, Luke Mason, Andreas Meyer-Lindenberg, Carolin Moessnang, Nico Mueller, Laurence O’Dwyer, Marianne Oldehinkel, Bob Oranje, Gahan Pandina, Antonio M. Persico, Barbara Ruggeri, Amber N. V. Ruigrok, Jessica Sabet, Roberto Sacco, Antonia San Jóse Cáceres, Emily Simonoff, Roberto Toro, Heike Tost, Jack Waldman, Steve C. R. Williams, Marcel P. Zwiers, Will Spooren, Declan G. M. Murphy, Jan K. Buitelaar

Publikováno v: Molecular Autism, Vol 8, Iss 1, Pp 1-21 (2017)

Abstract Background The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes the clinical charact

Externí odkaz: https://doaj.org/article/108c6acd8c3346ed894058061f4864ea

Functional MRI of emotional memory in adolescent depression

Autor: Rosemary J. Holt, Julia M. Graham, Kirstie J. Whitaker, Cindy C. Hagan, Cinly Ooi, Paul O. Wilkinson, Adrienne O. van Nieuwenhuizen, Belinda R. Lennox, Barbara J. Sahakian, Ian M. Goodyer, Edward T. Bullmore, John Suckling

Publikováno v: Developmental Cognitive Neuroscience, Vol 19, Iss C, Pp 31-41 (2016)

Introduction: Major Depressive Disorder (MDD) is a leading cause of disease burden worldwide. Mood-congruent biases in memory tasks are frequently reported in MDD patients, with facilitated memory for negative stimuli. Most functional MRI studies to

Externí odkaz: https://doaj.org/article/b433933663784f3bafb39d14ab2a856f

Adolescent Major Depressive Disorder: Neuroimaging Evidence of Sex Difference during an Affective Go/No-Go Task

Autor: Jie-Yu Chuang, Cindy C. Hagan, Graham K. Murray, Julia M. E. Graham, Cinly Ooi, Roger Tait, Rosemary J. Holt, Rebecca Elliott, Adrienne O. van Nieuwenhuizen, Edward T. Bullmore, Belinda R. Lennox, Barbara J. Sahakian, Ian M. Goodyer, John Suckling

Publikováno v: Frontiers in Psychiatry, Vol 8 (2017)

Compared to female major depressive disorder (MDD), male MDD often receives less attention. However, research is warranted since there are significant sex differences in the clinical presentation of MDD and a higher rate of suicide in depressed men.

Externí odkaz: https://doaj.org/article/ca283673a5944a61afb1878adeba006b