Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rosemary, Watt"'
Autor:
Elliot S. Barnathan, Eric Wadman, Carrie Brodmerkel, Calixte S. Monast, Rosemary Watt, Marc A. Judson, Katherine Li, Philip E. Silkoff, Robert P. Baughman
Summary The molecular basis of sarcoidosis phenotype heterogeneity and its relationship to effective treatment of sarcoidosis have not been elucidated. Peripheral samples from sarcoidosis subjects who participated in a Phase II study of golimumab [an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e6e2cf5c2a94987ef4ce247450b2f0
https://europepmc.org/articles/PMC5422855/
https://europepmc.org/articles/PMC5422855/
Autor:
Susan FitzPatrick, Georgette Stern, Regula Nydegger, D. Robin Taylor, Cindy Thamrin, Sally E. Wenzel, Urs Frey, Pascal Chanez, Rosemary Watt
Publikováno v:
Thorax. 66:1036-1042
Lung function is a major criterion used to assess asthma control. Fluctuation analyses can account for lung function history over time, and may provide an additional dimension to characterise control. The relationships between mean and fluctuations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc91cb2bc84de7f05f3356a413f7fe0e
https://doi.org/10.1136/thx.2010.156489
https://doi.org/10.1136/thx.2010.156489
Autor:
Sally E, Wenzel, Peter J, Barnes, Eugene R, Bleecker, Jean, Bousquet, William, Busse, Sven-Erik, Dahlén, Stephen T, Holgate, Deborah A, Meyers, Klaus F, Rabe, Adam, Antczak, James, Baker, Ildiko, Horvath, Zsuzsanna, Mark, David, Bernstein, Edward, Kerwin, Rozsa, Schlenker-Herceg, Kim Hung, Lo, Rosemary, Watt, Elliot S, Barnathan, Pascal, Chanez, E H, Bel
Publikováno v:
American journal of respiratory and critical care medicine, 179(7), 549-558. American Thoracic Society
Rationale The treatment effect of golimumab, a human monoclonal antibody against tumor necrosis factor (TNF)-alpha, in severe persistent asthma is unknown. Objectives To assess the safety and efficacy of golimumab in a large population of patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c0f2c63111182d318d3bd90337039f
https://doi.org/10.1164/rccm.200809-1512oc
https://doi.org/10.1164/rccm.200809-1512oc
Autor:
Steven G. Kelsen, James Allison, Thomas Siler, Kim Hung Lo, Joe W. Ramsdell, Charles E. Andrews, Rozsa Schlenker-Herceg, Rosemary Watt, Stephen I. Rennard, Michael Mandel, John J. Murray, Phillip Korenblat, Elliot S. Barnathan, William L. Smith, Mitchell Kaye, William Long, Constantine Saadeh, James F. Donohue, Rachakonda Prabhu, Charles Fogarty, Phillip Snell, Donald A. Mahler
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 175:926-934
Chronic obstructive pulmonary disease (COPD) is a progressive, smoking-related, inflammatory lung disease in which tumor necrosis factor-alpha is overexpressed and has been suggested to play a pathogenic role.To determine if infliximab, an anti-TNF-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a296ee28ccf876a187b0d63081f4b2e5
https://doi.org/10.1164/rccm.200607-995oc
https://doi.org/10.1164/rccm.200607-995oc
Autor:
Elliot S Barnathan, Michael Mack, David Victorson, Jennifer L. Beaumont, Rosemary Watt, Marc A. Judson
Publikováno v:
American journal of respiratory and critical care medicine. 191(7)
Patient-reported outcome (PRO) measures have been developed to measure symptoms and other aspects of health-related quality of life.The Sarcoidosis Assessment Tool (SAT), a sarcoidosis-specific PRO, was administered in a lung and skin sarcoidosis tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c65ebfbe29f89a31271543ec04387f7
https://pubmed.ncbi.nlm.nih.gov/25594886
https://pubmed.ncbi.nlm.nih.gov/25594886
Autor:
Carlo Albera, Joseph Barney, Robert P. Baughman, Ulrich Costabel, Isham Huizar, Nabeel Hamzeh, Carrie Brodmerkel, Prasheen Agarwal, Hidenobu Shigemitsu, Marjolein Drent, Rosemary Watt, Ganesh Raghu, Marc A. Judson, Elliot S. Barnathan, Daniel A. Culver, Marlies S. Wijsenbeek, Kevin F. Gibson
Publikováno v:
European Respiratory Journal, 44(5), 1296-1307. European Respiratory Society
Sarcoidosis is characterised by non-caseating granulomas that secrete pro-inflammatory cytokines, including interleukin (IL)-12, IL-23, and tumour necrosis factor (TNF)-α. Ustekinumab and golimumab are monoclonal antibodies that specifically inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c62e6172b0d750b4f5be1d999cd3b1c3
Autor:
Sally E. Wenzel, Urs Frey, Susan FitzPatrick, Joel Zindel, Cindy Thamrin, Regula Nydegger, Rosemary Watt, Pascal Chanez, Béla Suki, Helen K. Reddel
Publikováno v:
The Journal of allergy and clinical immunology. 127(6)
Background Determination of future risk of exacerbations is a key issue in the management of asthma. We previously developed a method to calculate conditional probabilities (π) of future decreases in lung function by using the daily fluctuations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc1f76b0ff5ab277c636e11fc4e2123
https://pubmed.ncbi.nlm.nih.gov/21536320
https://pubmed.ncbi.nlm.nih.gov/21536320
Publikováno v:
Respiratory Research
Respiratory Research, Vol 13, Iss 1, p 12 (2012)
Respiratory Research, Vol 13, Iss 1, p 12 (2012)
Background Chronic obstructive pulmonary disease (COPD) is characterized by progressive worsening of airflow limitation associated with abnormally inflamed airways in older smokers. Despite correlative evidence for a role for tumor necrosis factor-al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234b199560cc6e8e2ab27976152a7c14
http://europepmc.org/articles/PMC3287122
http://europepmc.org/articles/PMC3287122
Autor:
Richard E. Lafond, Rosemary Watt, Claude A. Villee, Peter H. Schur, Roger B. Eaton, Jeffrey K. Actor
Publikováno v:
Autoimmunity. 13(3)
Sera from U.S. patients with SLE, RA, and various malignancies, clinically normal individuals with sero-activity to HIV, AIDS, and from pregnant women were tested for the presence of anti-c-myc antibodies. In an ELISA using recombinant human c-myc pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f23a18c0e059c1dfed4fa1b7b51a90
https://pubmed.ncbi.nlm.nih.gov/1472633
https://pubmed.ncbi.nlm.nih.gov/1472633
Publikováno v:
Journal of Allergy and Clinical Immunology. 121:798
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a43fd26a5c4d4c8b88cddde238ce0fc
https://doi.org/10.1016/j.jaci.2008.01.065
https://doi.org/10.1016/j.jaci.2008.01.065