Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rosemary, Millen"'
Autor:
Arnon P. Kater, Barbara F. Eichhorst, Carolyn J. Owen, Ulrich Jaeger, Brenda Chyla, Marcus Lefebure, Rosemary Millen, Yanwen Jiang, Maria Thadani‐Mulero, Michelle Boyer, John F. Seymour
Publikováno v:
HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract Immune dysregulation is a hallmark of chronic lymphocytic leukemia (CLL). Anti‐CD20 antibodies (e.g., rituximab [R]) can be combined with venetoclax (Ven) to treat CLL. However, anti‐CD20 antibodies can increase hypogammaglobulinemia ris
Externí odkaz:
https://doaj.org/article/e7a1b35722c44499b7700a85cc48aca9
Autor:
Arnon Kater, Rosemary Harrup, Thomas J Kipps, Barbara Eichhorst, Carolyn J Owen, Sarit Assouline, Nicole Lamanna, Tadeusz Robak, Javier de la Serna, Ulrich Jaeger, Guillaume Cartron, Marco Montillo, Clemens Mellink, Brenda Chyla, Maria Thadani-Mulero, Marcus Lefebure, Yanwen Jiang, Rosemary Millen, Michelle Boyer, John F Seymour
Publikováno v:
HemaSphere, Vol 7, p e492813f (2023)
Externí odkaz:
https://doaj.org/article/40a72c8b5e324b6bb0a316c864da72a7
Autor:
Emma V. Petley, Hui-Fern Koay, Melissa A. Henderson, Kevin Sek, Kirsten L. Todd, Simon P. Keam, Junyun Lai, Imran G. House, Jasmine Li, Magnus Zethoven, Amanda X. Y. Chen, Amanda J. Oliver, Jessica Michie, Andrew J. Freeman, Lauren Giuffrida, Jack D. Chan, Angela Pizzolla, Jeffrey Y. W. Mak, Timothy R. McCulloch, Fernando Souza-Fonseca-Guimaraes, Conor J. Kearney, Rosemary Millen, Robert G. Ramsay, Nicholas D. Huntington, James McCluskey, Jane Oliaro, David P. Fairlie, Paul J. Neeson, Dale I. Godfrey, Paul A. Beavis, Phillip K. Darcy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Mucosal-associated invariant T (MAIT) cells facilitate anti-microbial responses, but their functions in cancer protection is unclear. Here the authors show that activated MAIT cells induce an IFN-γ transcriptome in natural killer (NK) cells and enha
Externí odkaz:
https://doaj.org/article/01f893fc7b8b403cadf95ab8ec274a3e
Autor:
Rosemary Millen, Shona Hendry, Vignesh Narasimhan, Rebecca Abbott, Matthew Croxford, Peter Gibbs, Jeanne Tie, Hui‐Li Wong, Ian Jones, Suzanne Kosmider, David Byrne, John Zalcberg, Stephen Fox, Jayesh Desai, Kumar Visvanathan, Robert G Ramsay, Ben Tran
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Objectives Tumor‐infiltrating lymphocytes (TIL), particularly CD8+ TILs in patients with colorectal cancer (CRC), are highly prognostic in the early‐disease stages (I‐II). In metastatic disease (stage IV; mCRC), their influence is less
Externí odkaz:
https://doaj.org/article/b19af94bbd8c4e68923ccae799bff469
Autor:
Maria Bolther, Karen Lise Dahl Andersen, Martin Tolstrup, Kumar Visvanathan, Ian Woolley, Narelle Skinner, Rosemary Millen, Nadia Warner, Lars Østergaard, Søren Jensen-Fangel
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 6, Pp 1483-1488 (2018)
This study investigated the immunomodulatory influence of IL10 producing B regulatory cells, Bregs (CD19+CD24hiCD38hi) to standard Twinrix® vaccination. We also investigated HBsAg specific T-cell mediated IFN-γ responses to Twinrix® which in theor
Externí odkaz:
https://doaj.org/article/e958e5d61940447c874b5d1defbe17a0
Autor:
Samuel A L Hall, Gareth S Burns, Benjamin J Mooney, Rosemary Millen, Rachel Morris, Sara Vogrin, Vijaya Sundararajan, Dilip Ratnam, Miriam T Levy, John S Lubel, Amanda J Nicoll, Simone I Strasser, William Sievert, Paul V Desmond, Meng C Ngu, Peter Angus, Marie Sinclair, Christopher Meredith, Gail Matthews, Peter A Revill, Kathy Jackson, Margaret Littlejohn, Scott Bowden, Stephen A Locarnini, Alexander J Thompson, Kumar Visvanathan
Publikováno v:
The Journal of Infectious Diseases. 227:123-132
Background We evaluated the patterns of peripheral Toll-like receptor (TLR) signaling activity and the expression of TLRs and natural killer (NK) cell activation in a cohort of patients experiencing severe hepatitis flares after stopping nucleot(s)id
Autor:
Arnon P. Kater, Barbara Eichhorst, Carolyn Owen, Ulrich Jaeger, Brenda Chyla, Marcus Lefebure, Rosemary Millen, Yanwen Jiang, Maria Thadani-Mulero, John F. Seymour
Publikováno v:
Blood. 140:7010-7012
Autor:
Rosemary Millen, Willem W.B. De Kort, Mandy Koomen, Gijs J.F. van Son, Roán Gobits, Bas Penning de Vries, Harry Begthel, Maurice Zandvliet, Patricia Doornaert, Cornelis P.J. Raaijmakers, Maarten H. Geurts, Sjoerd G. Elias, Robert J.J. van Es, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Onno Kranenburg, Else Driehuis, Hans Clevers
Publikováno v:
Med, 4(5), 290-310.e12
Background: Organoids are in vitro three-dimensional structures that can be grown from patient tissue. Head and neck cancer (HNC) is a collective term used for multiple tumor types including squamous cell carcinomas and salivary gland adenocarcinomas
Autor:
Johanna F. Dekkers, Maria Alieva, Astrid Cleven, Farid Keramati, Amber K. L. Wezenaar, Esmée J. van Vliet, Jens Puschhof, Peter Brazda, Inez Johanna, Angelo D. Meringa, Heggert G. Rebel, Maj-Britt Buchholz, Mario Barrera Román, Amber L. Zeeman, Sam de Blank, Domenico Fasci, Maarten H. Geurts, Annelisa M. Cornel, Else Driehuis, Rosemary Millen, Trudy Straetemans, Mara J. T. Nicolasen, Tineke Aarts-Riemens, Hendrikus C. R. Ariese, Hannah R. Johnson, Ravian L. van Ineveld, Froso Karaiskaki, Oded Kopper, Yotam E. Bar-Ephraim, Kai Kretzschmar, Alexander M. M. Eggermont, Stefan Nierkens, Ellen J. Wehrens, Henk G. Stunnenberg, Hans Clevers, Jürgen Kuball, Zsolt Sebestyen, Anne C. Rios
Publikováno v:
Nature Biotechnology. Nature Publishing Group
Extending the success of cellular immunotherapies against blood cancers to the realm of solid tumors will require improved in vitro models that reveal therapeutic modes of action at the molecular level. Here we describe a system, called BEHAV3D, deve
Autor:
Samuel Al, Hall, Gareth S, Burns, Benjamin J, Mooney, Rosemary, Millen, Rachel, Morris, Sara, Vogrin, Vijaya, Sundararajan, Dilip, Ratnam, Miriam T, Levy, John S, Lubel, Amanda J, Nicoll, Simone I, Strasser, William, Sievert, Paul V, Desmond, Meng C, Ngu, Peter, Angus, Marie, Sinclair, Christopher, Meredith, Gail, Matthews, Peter A, Revill, Kathy, Jackson, Margaret, Littlejohn, Scott, Bowden, Stephen A, Locarnini, Alexander J, Thompson, Kumar, Visvanathan
Publikováno v:
The Journal of infectious diseases.
We evaluated the patterns of peripheral TLR signalling activity and the expression of TLRs and NK cell activation in a cohort of patients experiencing severe hepatitis flares after stopping NA therapy.Samples were collected longitudinally from CHB pa