Supplementary Methods and References from Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination

Autor: Nicolaas A.P. Franken, Perry D. Moerland, Lukas J.A. Stalpers, Harry Vrieling, Jan Paul Medema, Rosemarie ten Cate, Ilja Oomen, Lon Uitterhoeve, Bregje van Oorschot

Description of additional methods and procedures used in the study. Also includes Supplementary References.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a451fca3dfdcf167f172e0200a8c29a8
https://doi.org/10.1158/0008-5472.22416243.v1

Supplementary Figures S1-S5 from Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination

Autor: Nicolaas A.P. Franken, Perry D. Moerland, Lukas J.A. Stalpers, Harry Vrieling, Jan Paul Medema, Rosemarie ten Cate, Ilja Oomen, Lon Uitterhoeve, Bregje van Oorschot

Receiver operating characteristic (ROC) curve and foci decay ratios from our retrospective study ; Induction of gene expression upon irradiation calculated within each individual patient (indicated by the index on the x-axis) for three selected radia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a6e846a921f059809d59d79f544c76
https://doi.org/10.1158/0008-5472.22416246.v1

Supplementary Figure S4 from Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis

Autor: Nicolaas A.P. Franken, Jan Paul Medema, H. Petra Kok, Johannes Crezee, Lukas J.A. Stalpers, Marrije R. Buist, Hans M. Rodermond, Rosemarie ten Cate, Caspar M. van Leeuwen, Arlene L. Oei

Induction of apoptosis determined using Nicoletti assay in HPV-positive and HPV-negative cells after radiation, hyperthermia and combined treatment in the presence or absence of P53-siRNA,cDDP, chloroquine or MG-132.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad1c78d32da32f29dfe8f296a56052c
https://doi.org/10.1158/0008-5472.22405287

Data from Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis

Autor: Nicolaas A.P. Franken, Jan Paul Medema, H. Petra Kok, Johannes Crezee, Lukas J.A. Stalpers, Marrije R. Buist, Hans M. Rodermond, Rosemarie ten Cate, Caspar M. van Leeuwen, Arlene L. Oei

Human papillomavirus (HPV) is associated with cervical cancer, the third most common cancer in women. The high-risk HPV types 16 and 18 are found in over 70% of cervical cancers and produce the oncoprotein, early protein 6 (E6), which binds to p53 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bbfa5573821843d16667bc7a61f1a9
https://doi.org/10.1158/0008-5472.c.6506787.v1

Increased uptake of doxorubicin by cells undergoing heat stress does not explain its synergistic cytotoxicity with hyperthermia

Autor: Nicole M. Anders, Julia S. Caserto, Elizabeth Henderson, Anirudh Sharma, Fred Bunz, Michelle A. Rudek, Nicolaas A. P. Franken, James D. Barnett, Eleni Liapi, Rosemarie ten Cate, Arlene L. Oei, Sri Kamal Kandala, Sanem Özayral, Robert Ivkov, Jacqueline Stewart, Preethi Korangath

Publikováno v: International journal of hyperthermia, 36(1), 712-720. Informa Healthcare
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
International Journal of Hyperthermia, Vol 36, Iss 1, Pp 711-719 (2019)

Purpose: A proposed mechanism for the enhanced effectiveness of hyperthermia and doxorubicin (Dox) combinations is increased intracellular Dox concentrations resulting from heat-induced cell stress. The purpose of this study was to determine whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7742297b2084cca5dc18e559d8fa781
https://pure.amc.nl/en/publications/increased-uptake-of-doxorubicin-by-cells-undergoing-heat-stress-does-not-explain-its-synergistic-cytotoxicity-with-hyperthermia(04979d4b-812d-4f37-a6b4-86011f9d7df6).html