Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rosemarie W. Tsoa"'
Autor:
Yi E. Sun, Yin Cheng, Rosemarie W. Tsoa, Zoë MacDowell Kaswan, Quan Li, Cristina A. Ghiani, Daniel D. Truong, Matthew Derakhshesh, Christopher S. Colwell, Dawn H. Loh, Takashi Kudo
Publikováno v:
Neurobiology of Disease, Vol 77, Iss, Pp 155-164 (2015)
Disturbances in the sleep/wake cycle are prevalent in patients with Rett syndrome (RTT). We sought to determine whether the circadian system is disrupted in a RTT model, Mecp2(-/y) mice. We found that MeCP2 mutants showed decreased strength and preci
Autor:
Rosemarie W. Tsoa, Claudia C. Aguirre, Rita M. Kern, Hong Yu, Paul K. Yoo, Stephen D. Cederbaum, Wayne W. Grody, Ramaswamy K. Iyer
Publikováno v:
Journal of Histochemistry & Cytochemistry. 51:1151-1160
Arginase I (AI), the fifth and final enzyme of the urea cycle, detoxifies ammonia as part of the urea cycle. In previous studies from others, AI was not found in extrahepatic tissues except in primate blood cells, and its roles outside the urea cycle
Autor:
Stephen D. Cederbaum, Nora Rozengurt, Wayne W. Grody, Ramaswamy K. Iyer, Paul K. Yoo, Rita M. Kern, William E. O'Brien, Rosemarie W. Tsoa, Hong Yu
Publikováno v:
Molecular and Cellular Biology. 22:4491-4498
Deficiency of liver arginase (AI) causes hyperargininemia (OMIM 207800), a disorder characterized by progressive mental impairment, growth retardation, and spasticity and punctuated by sometimes fatal episodes of hyperammonemia. We constructed a knoc
Publikováno v:
Molecular Genetics and Metabolism. 75:209-218
Arginine decarboxylase (ADC) and agmatinase are part of an operon in Escherichia coli, which constitutes the primary pathway of polyamine synthesis from arginine. This pathway is also known to exist in plants, but until recently, neither agmatine nor
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(20)
The studies on the exact lineage composition of NG2 expressing progenitors in the forebrain have been controversial. A number of studies have revealed the heterogeneous nature of postnatal NG2 cells. However, NG2 cells found in embryonic dates are fa
Publikováno v:
Current opinion in neurobiology. 22(5)
Many lineage-specific genes are poised and silenced in stem cells. Upon differentiation, genes that are related to self-renewal and alternative lineages are stably silenced. CpG methylation at proximal promoters and PRC2-mediated H3K27me3 play a role