Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rosemarie Ungricht"'
Autor:
Naemi Luithle, Jelmi uit de Bos, Ruud Hovius, Daria Maslennikova, Renard TM Lewis, Rosemarie Ungricht, Beat Fierz, Ulrike Kutay
Publikováno v:
eLife, Vol 9 (2020)
The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet h
Externí odkaz:
https://doaj.org/article/679c993e628941b28e46150ce42c759e
Publikováno v:
eLife, Vol 6 (2017)
Newly synthesized membrane proteins are targeted to the inner nuclear membrane (INM) by diffusion within the membrane system of the endoplasmic reticulum (ER), translocation through nuclear pore complexes (NPCs) and retention on nuclear partners. Usi
Externí odkaz:
https://doaj.org/article/900938b06bf7471b821a53e3f3b8e6bc
Autor:
Antoine Buetti‐Dinh, Rosemarie Ungricht, János Z Kelemen, Chetak Shetty, Prasuna Ratna, Attila Becskei
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-8 (2009)
Abstract A transcriptional activator can suppress gene expression by interfering with transcription initiated by another activator. Transcriptional interference has been increasingly recognized as a regulatory mechanism of gene expression. The signal
Externí odkaz:
https://doaj.org/article/1969204731764bb5b9d93874a5ec8b97
Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis
Publikováno v:
Molecular Biology of the Cell, 30 (4)
Molecular Biology of the Cell
Molecular Biology of the Cell
Molecular Biology of the Cell, 30 (4)
ISSN:1939-4586
ISSN:1059-1524
ISSN:1939-4586
ISSN:1059-1524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c13466256477520d45102c4eaa47cd9
https://doi.org/10.1091/mbc.e18-10-0609
https://doi.org/10.1091/mbc.e18-10-0609
Autor:
Guglielmo Roma, Walter Carbone, Philipp S. Hoppe, Florian Nigsch, Rosemarie Ungricht, Rachel Cuttat, Dominic Hoepfner, Orsini, Guibbal L, Martin Beibel, Anne Basler, Jan S. Tchorz, Marie-Christine Lasbennes, Annick Waldt
Human organoids allow studying proliferation, lineage specification, and three-dimensional tissue development. Due to the inherent multicellular complexity, interrogation by systematic genetic methodologies is challenging. Here, we present the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5367f3696281da4bfa2aa90e43e89eda
https://doi.org/10.1101/2021.05.26.445745
https://doi.org/10.1101/2021.05.26.445745
SUMMARYThe loss or failure of cell differentiation is a hallmark of cancer, yet whether perturbation of differentiation is causal or consequential to malignant transformation is largely unclear. Wilms tumor is the most widespread kidney cancer in chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218e0c9333d0a59c39790d6f77a8cf24
https://doi.org/10.1101/2021.02.02.429313
https://doi.org/10.1101/2021.02.02.429313
Autor:
Jelmi uit de Bos, Daria Maslennikova, Ulrike Kutay, Renard Tm Lewis, Beat Fierz, Ruud Hovius, Rosemarie Ungricht, Naemi Luithle
Publikováno v:
eLife, 9
eLife
eLife, Vol 9 (2020)
eLife
eLife, Vol 9 (2020)
The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f592d046467d85877e6cb7e7dcb71a3
https://hdl.handle.net/20.500.11850/461818
https://hdl.handle.net/20.500.11850/461818
Autor:
Florian Nigsch, Guglielmo Roma, Jan S. Tchorz, Rosemarie Ungricht, Dominic Hoepfner, Rachel Cuttat, Vanessa Orsini, Anne Basler, Marie-Christine Lasbennes, Martin Beibel, Philipp S. Hoppe, Walter Carbone, Annick Waldt, Laure Guibbal
Publikováno v:
Cell Stem Cell. 29:160-175.e7
Summary Human organoids allow the study of proliferation, lineage specification, and 3D tissue development. Here we present a genome-wide CRISPR screen in induced pluripotent stem cell (iPSC)-derived kidney organoids. The combination of inducible gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8399f66f43ad25811f94a01119576e4
https://doi.org/10.1016/j.stem.2021.11.001
https://doi.org/10.1016/j.stem.2021.11.001
Publikováno v:
The Journal of Cell Biology
Data from a new in vitro assay measuring inner nuclear membrane (INM) targeting kinetics as well as from mathematical modeling support a diffusion-retention–based mechanism of INM targeting.
Newly synthesized membrane proteins are constantly s
Newly synthesized membrane proteins are constantly s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c57f6e83e4f1b44937406a7d6f6be82
https://doi.org/10.1083/jcb.201409127
https://doi.org/10.1083/jcb.201409127