Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rosemarie J. E. Joordens"'
Publikováno v:
NeuroReport. 11:2285-2288
In a previous study it was demonstrated that flesinoxan, a selective serotonin (5-HT)1A receptor agonist, had anxiolytic properties in the fear-potentiated startle paradigm. The present study investigated the putative site of action of flesinoxan in
Publikováno v:
Psychopharmacology. 139:383-390
The present study investigated whether the anxiolytic effect of 5-HT1A receptor agonists on the fear-potentiated startle response could be antagonized by 5-HT1A receptor antagonists. Therefore, control and fear-potentiated startle amplitudes were mea
Autor:
Berend Olivier, Christina M.F King, Rosemarie J. E. Joordens, Theo H. Hijzen, Jan Gommans, Robert A. A. Maes
Publikováno v:
European Journal of Pharmacology. 325:121-128
In a modified Geller-Seifter conflict procedure, rats were trained to lever-press for food under a multiple variable interval-fixed ratio (VI30: food; FR10: food + shock) schedule of reinforcement. The ability to antagonize response suppression in th
Publikováno v:
Life sciences. 63(25)
In the present study, the effects of alprazolam, chlordiazepoxide, ethanol and haloperidol in the strychnine-potentiated startle response paradigm were investigated. Because strychnine increases control startle levels without fear-conditioning, no ce
Publikováno v:
Neuroreport. 8(4)
In the present study, the fear-potentiated startle response paradigm was modified in order to investigate the decrease in control startle levels often observed after administration of anxiolytic drugs. The within-animal comparison of control startle
Publikováno v:
Psychopharmacology. 126(2)
The fear-potentiated startle response paradigm is used to investigate anxiolytic properties of drugs. The first objective of the present study was to further investigate the predictive validity of this paradigm. The anxiolytics chlordiazepoxide (2.5-
Publikováno v:
Psychopharmacology. 118(2)
The fear-potentiated startle (PSR) paradigm is a putative behavioral model for the determination of anxiolytic properties of drugs. The present study further investigated the predictive validity of the model. Predictive validity is high, when only dr
Autor:
Theo H. Hijzen, J.M.N. Coolen, Rosemarie J. E. Joordens, Lucianne Groenink, J. van der Gugten
Publikováno v:
Behavioural Processes. 29:131-132