Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rosemarie Aurigemma"'
Autor:
Nirali Shah, Lili Yang, Kasia Bourcier, Antoni Ribas, Pawel Kalinski, Ke Liu, Phil Greenberg, Carl June, Marcela Maus, Steven Rosenberg, Madhav Dhodapkar, Irina Tiper, Chantale Bernatchez, Michael Hudecek, Stanley Riddell, Stephen Gottschalk, Crystal Mackall, Lisa Butterfield, Greg Delgoffe, Michael Nishimura, Terry Fry, Marc S. Ernstoff, Christopher Klebanoff, Elad Sharon, Malcolm Brenner, Cliona Rooney, Christine Brown, Marc S Ernstoff, Tonya Webb, Magdalena Thurin, Wendell Lim, David Stroncek, Catherine Bollard, Helen Chen, Cameron Turtle, Christian Hinrichs, Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Steven Albelda, Renier Brentjens, Yvonne Chen, Laronna Colbert, Kenneth Cornetta, Jason Cristofaro, Thomas Finn, Laura K Fogli Hunter, Alyssa Galaro, Ananda Goldrath, Ray Harris, Lori Henderson, Yuxia Jia, Dan Kaufman, Bruce Levine, Lawrence Lum, Samantha Maragh, Alex Marson, Raj Puri, Jake Reder, Isabelle Riviere, Kole Roybal, Rachelle Salomon, Tal Salz, Barbra Sasu, Andrea Schietinger, Connie L. Sommers, Minkyung Song, Fyodor Urnov, Anthony Welch, Travis Young, Jason Yovandich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Cell-based immunotherapies have had remarkable success in the clinic, specifically in the treatment of hematologic malignancies. However, these strategies have had limited efficacy in patients with solid tumors. To better understand the challenges in
Externí odkaz:
https://doaj.org/article/f4500c9773db47d7abfb74eccac2d857
Autor:
Rebecca Lipsitz, Susan Garges, Rosemarie Aurigemma, Prasith Baccam, David D. Blaney, Allen C. Cheng, Bart J. Currie, David Dance, Jay E. Gee, Joseph Larsen, Direk Limmathurotsakul, Meredith G. Morrow, Robert Norton, Elizabeth O’Mara, Sharon J. Peacock, Nicki Pesik, L. Paige Rogers, Herbert P. Schweizer, Ivo Steinmetz, Gladys Tan, Patrick Tan, W. Joost Wiersinga, Vanaporn Wuthiekanun, Theresa L. Smith
Publikováno v:
Emerging Infectious Diseases, Vol 18, Iss 12, Pp - (2012)
The US Public Health Emergency Medical Countermeasures Enterprise convened subject matter experts at the 2010 HHS Burkholderia Workshop to develop consensus recommendations for postexposure prophylaxis against and treatment for Burkholderia pseudomal
Externí odkaz:
https://doaj.org/article/5202ba97436b4303bc57bfb60f85d843
Autor:
Ronald D. Alvarez, David T. Curiel, Kurt R. Zinn, Gene P. Siegal, Rosemarie Aurigemma, Raymond D. Harris, Meredith A. Preuss, Zhiying You, Souheil Saddekni, Minghui Wang, Janis P. O'Malley, Igor Dmitriev, Kenneth H. Kim
PDF file - 43K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6885887cd3ad13f74e38ed8dcadc41
https://doi.org/10.1158/1078-0432.22444520.v1
https://doi.org/10.1158/1078-0432.22444520.v1
Autor:
Ronald D. Alvarez, David T. Curiel, Kurt R. Zinn, Gene P. Siegal, Rosemarie Aurigemma, Raymond D. Harris, Meredith A. Preuss, Zhiying You, Souheil Saddekni, Minghui Wang, Janis P. O'Malley, Igor Dmitriev, Kenneth H. Kim
PDF file - 81K, Supplementary Table 2 Primers and probe sets utilized in this study were designed by the Primer Express 1.5 software and synthesized by Sigma-Aldrich. These primers and probes were utilized for quantitative PCR in ancillary biologic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ea42add38f13fc2f9e4424c207cc40
https://doi.org/10.1158/1078-0432.22444514
https://doi.org/10.1158/1078-0432.22444514
Autor:
Ronald D. Alvarez, David T. Curiel, Kurt R. Zinn, Gene P. Siegal, Rosemarie Aurigemma, Raymond D. Harris, Meredith A. Preuss, Zhiying You, Souheil Saddekni, Minghui Wang, Janis P. O'Malley, Igor Dmitriev, Kenneth H. Kim
PDF file - 106K, Patients were then assigned into one of three Ad5.SSTR/TK.RGD dose cohorts ranging from 1 x 109 vp/d to 1 x 1012 vp/d (6 x 107 pfu/d to 6 x 1010 pfu/d). This dose administration strategy has been validated in our preclinical studies;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c703bb2ad04fda9ebe48795be95725d
https://doi.org/10.1158/1078-0432.22444523.v1
https://doi.org/10.1158/1078-0432.22444523.v1
Autor:
Ronald D. Alvarez, David T. Curiel, Kurt R. Zinn, Gene P. Siegal, Rosemarie Aurigemma, Raymond D. Harris, Meredith A. Preuss, Zhiying You, Souheil Saddekni, Minghui Wang, Janis P. O'Malley, Igor Dmitriev, Kenneth H. Kim
Purpose: Ad5.SSTR/TK.RGD is an infectivity-enhanced adenovirus expressing a therapeutic thymidine kinase suicide gene and a somatostatin receptor (SSTR) that allows for noninvasive gene transfer imaging. The purpose of this study was to identify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac21ac75f9f690a18fa1ff9e5cb393c
https://doi.org/10.1158/1078-0432.c.6520214.v1
https://doi.org/10.1158/1078-0432.c.6520214.v1
Autor:
Ronald D. Alvarez, David T. Curiel, Kurt R. Zinn, Gene P. Siegal, Rosemarie Aurigemma, Raymond D. Harris, Meredith A. Preuss, Zhiying You, Souheil Saddekni, Minghui Wang, Janis P. O'Malley, Igor Dmitriev, Kenneth H. Kim
PDF file - 51K, Patients were then assigned into one of three Ad5.SSTR/TK.RGD dose cohorts ranging from 1 x 109 vp/d to 1 x 1012 vp/d (6 x 107 pfu/d to 6 x 1010 pfu/d). This dose administration strategy has been validated in our preclinical studies;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373614ca9eed6958b07bedc762f8e6f6
https://doi.org/10.1158/1078-0432.22444517.v1
https://doi.org/10.1158/1078-0432.22444517.v1
Autor:
Kenneth H. Kim, Rosemarie Aurigemma, Sejong Bae, Souheil Saddekni, David T. Curiel, Karan P. Singh, Ronald D. Alvarez, Igor P. Dmitriev, Raymond D. Harris, Gene P. Siegal, Elena A. Kashentseva
Publikováno v:
Gynecologic Oncology. 130:518-524
Objective The conditionally replicative adenovirus Ad5/3-Δ24 has a type-3 knob incorporated into the type-5 fiber that facilitates enhanced ovarian cancer infectivity. Preclinical studies have shown that Ad5/3-Δ24 achieves significant oncolysis and
Autor:
Brock M. Miniard, James O. Peggins, Raymond D. Harris, Ronald D. Alvarez, Thomas L. Rudge, Akseli Hemminki, Meredith A. Preuss, Minghui Wang, David T. Curiel, Rosemarie Aurigemma, Trevor Broadt, Michael J. Ryan, Gene P. Siegal, Kenneth H. Kim, James E. Estep
Publikováno v:
Human Gene Therapy. 22:821-828
Conditionally replicative adenoviral (CRAd) virotherapy represents a promising therapeutic approach for cancer. We have demonstrated that a serotype chimeric adenoviral 5/3 fiber-knob modification achieves enhanced ovarian cancer infectivity, conditi
Autor:
Wen Wan, Gene P. Siegal, Ronald D. Alvarez, Minghui Wang, Rosemarie Aurigemma, Souheil Saddekni, David T. Curiel, Mack N. Barnes, Meredith A. Preuss, Cecil R. Stockard, Huichien Kuo, William E. Grizzle, Raymond D. Harris, Kristopher J. Kimball
Publikováno v:
Clinical Cancer Research. 16:5277-5287
Purpose: To determine the maximum tolerated dose (MTD), toxicity spectrum, clinical activity, and biological effects of the tropism-modified, infectivity-enhanced conditionally replicative adenovirus (CRAd), Ad5–Δ24–Arg-Gly-Asp (RGD), in patient