Oral and Intraperitoneal Administration of Phosphorothioate Oligodeoxynucleotides Leads to Control ofCryptosporidium parvumInfection in Neonatal Mice

Autor: Fabrice Laurent, Anne-Marie Chaussé, Satoshi Uematsu, Sonia Lacroix-Lamandé, Shizuo Akira, Nelly Bernardet, Mathieu Barrier, Gaël Auray, Roselyne Mancassola

Publikováno v: HAL
Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2006, 193 (10), pp.1400-1407. ⟨10.1086/503748⟩

International audience; Background. Neonates are particularly vulnerable to infections, in part because of the incomplete development of their immune system. Recent advances in immunostimulatory treatments based on conserved microbial components led

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa41df883f69006cb319d85cb783512
https://doi.org/10.1086/503748

Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora

Autor: Roselyne Mancassola, William Guesdon, Catherine Werts, Fabrice Laurent, Louis Lantier, Richard Lo-Man, Sonia Lacroix-Lamandé, Coralie Metton, Françoise Drouet

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2014, 209 (3), pp.457-467. ⟨10.1093/infdis/jit432⟩
Journal of Infectious Diseases, 2014, 209 (3), pp.457-467. ⟨10.1093/infdis/jit432⟩

International audience; The neonatal intestinal immune system is still undergoing development at birth, leading to a higher susceptibility to mucosal infections. In this study, we investigated the effect of poly(I:C) on controlling enteric infection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b0a306c511545ba1547e3f00a576d2
https://hal.inrae.fr/hal-02636084

Use of a non-adherent cell culture system for testing the effect of 2′,3′-dideoxyinosine againstCryptosporidium parvum

Autor: Marie-Elisabeth Sarciron, Philippe Lawton, Muriel Naciri, Anne-Françoise Petavy, Roselyne Mancassola, Carine Hejl

Publikováno v: FEMS Microbiology Letters
FEMS Microbiology Letters, Wiley-Blackwell, 1999, 176 (1), pp.235-240. ⟨10.1111/j.1574-6968.1999.tb13667.x⟩

International audience; The in vitro cultivation of Cryptosporidium parvum in the non-adherent cell line THP-1 was evaluated for its capability as a useful additional model to investigate the effect of drugs on this parasite. The purine analog antivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1ff1a89cf46a48bcc09888b212e6f9
https://doi.org/10.1111/j.1574-6968.1999.tb13667.x

CCR5 is involved in controlling the early stage of Cryptosporidium parvum infection in neonates but is dispensable for parasite elimination

Autor: Roselyne Mancassola, Gaël Auray, Sonia Lacroix-Lamandé, Fabrice Laurent, Nelly Bernardet

Publikováno v: Microbes and Infection
Microbes and Infection, Elsevier, 2008, 10 (4), pp.390-395. ⟨10.1016/j.micinf.2007.12.020⟩

International audience; Chemokines play a critical role in immune cell trafficking and the transition from an innate to an acquired immune response. We analyzed host response in neonatal mice deficient in chemokine receptor CCR5 following infection w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6c9f06ef3074ca6b4e1bc6ec46818e
https://pubmed.ncbi.nlm.nih.gov/18403229

Immunostimulation strategies to control neonatal diseases

Autor: Fabrice Laurent, Barrier, M., Roselyne Mancassola, Sonia LAMANDE

Publikováno v: International workshop on Protozoa orally transmitted in public and animal heath
International workshop on Protozoa orally transmitted in public and animal heath, Dec 2006, Nouzilly, France
HAL

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a86507636c54b5e9b4b3a78a4784c379
https://hal.inrae.fr/hal-02758467