Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Roselle, Abraham"'
Publikováno v:
Stresses, Vol 4, Iss 2, Pp 330-341 (2024)
The modern theory of stress, initially proposed by Hans Selye in 1956, signifies an important development in our understanding of this phenomenon. Selye’s The Stress of Life serves as a foundational book for subsequent scientific questions. In this
Externí odkaz:
https://doaj.org/article/ab4d685fc2874e6ba9bea4f74f11181c
Autor:
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100073- (2024)
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy. However, it is unknown whether a common metabolic trait underlies cardia
Externí odkaz:
https://doaj.org/article/d8cb9d6dcd734514bb112086143d8f7d
Autor:
Avantika Sinha, MSc, Xiaoxi Liu, PhD, Shuyu Tang, PhD, Nicholas Dwork, PhD, Sanjay Sivalokanathan, MD, Jing Liu, PhD, Robert Bok, MD, PhD, Karen Ordovas, MD, FSCMR, James Slater, PhD, Jeremy Gordon, PhD, Roselle Abraham, MD, Peder Larson, PhD
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100838- (2024)
Externí odkaz:
https://doaj.org/article/176cda86473544d9a718bd4a538157c1
Autor:
Ioannis Ventoulis, Vasileios Kamperidis, Maria Roselle Abraham, Theodore Abraham, Antonios Boultadakis, Efthymios Tsioukras, Aikaterini Katsiana, Konstantinos Georgiou, John Parissis, Effie Polyzogopoulou
Publikováno v:
Medicina, Vol 60, Iss 1, p 109 (2024)
Heart failure (HF) is characterized by a progressive clinical course marked by frequent exacerbations and repeated hospitalizations, leading to considerably high morbidity and mortality rates. Patients with HF present with a constellation of botherso
Externí odkaz:
https://doaj.org/article/db244f5281cc43b1873e9f805c2b4789
Autor:
Dai-Yin Lu, Ioannis Ventoulis, Hongyun Liu, Bereketeab Haileselassie, Iraklis Pozios, Hsin-Yueh Liang, Lars L. Sorensen, Marco Canepa, Nicole Bavaro, Susan Phillip, M. Roselle Abraham, Theodore P. Abraham
Publikováno v:
International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 16, Iss , Pp 200166- (2023)
Objective: Hypertensive response to exercise (HRE) is observed in patients with hypertrophic cardiomyopathy (HCM) with normal resting blood pressure (BP). However, the prevalence or prognostic implications of HRE in HCM remain unclear. Methods: In th
Externí odkaz:
https://doaj.org/article/e9788cc7303a4d8f9ba9070b9b192ee2
Autor:
Styliani Vakrou, Yamin Liu, Li Zhu, Gabriela V. Greenland, Bahadir Simsek, Virginia B. Hebl, Yufan Guan, Kirubel Woldemichael, Conover C. Talbot, Miguel A. Aon, Ryuya Fukunaga, M. Roselle Abraham
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM).
Externí odkaz:
https://doaj.org/article/e365172126d5471c8bde7c2cc906f5f3
Autor:
Michele Violano, Wolfgang Poller, Maria Roselle Abraham, Martin Huemer, Melvin Scheinman, Ulf Landmesser, Bettina Heidecker
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 41, Iss , Pp 101062- (2022)
Externí odkaz:
https://doaj.org/article/6a8c1c68b671448b9c2eeed3283804b9
Autor:
Ryan P O'Hara, Edem Binka, Adityo Prakosa, Stefan L Zimmerman, Mark J Cartoski, M Roselle Abraham, Dai-Yin Lu, Patrick M Boyle, Natalia A Trayanova
Publikováno v:
eLife, Vol 11 (2022)
Hypertrophic cardiomyopathy (HCM) is associated with risk of sudden cardiac death (SCD) due to ventricular arrhythmias (VAs) arising from the proliferation of fibrosis in the heart. Current clinical risk stratification criteria inadequately identify
Externí odkaz:
https://doaj.org/article/41a1869802864523a63dd249be178dd7
Publikováno v:
International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 11, Iss , Pp 200115- (2021)
Backgroud: Heart responds to physiologic and pathologic conditions and sympathetic drive plays an important role. It has been documented that LV base is more dominantly affected by sympathetic drive compared to the other regions. LV base is more domi
Externí odkaz:
https://doaj.org/article/6dbf82c25790470caa533328a21397f3
Autor:
Yamin Liu, Junaid Afzal, Styliani Vakrou, Gabriela V. Greenland, C. Conover Talbot, Virginia B. Hebl, Yufan Guan, Rehan Karmali, Jil C. Tardiff, Leslie A. Leinwand, Jeffrey E. Olgin, Samarjit Das, Ryuya Fukunaga, M. Roselle Abraham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Background: Hypertrophic cardiomyopathy (HCM) is characterized by myocyte hypertrophy and fibrosis. Studies in two mouse models (R92W-TnT/R403Q-MyHC) at early HCM stage revealed upregulation of endothelin (ET1) signaling in both mutants, but TGFβ si
Externí odkaz:
https://doaj.org/article/f0f284719e3944509201f2ec8335d642