Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Rosella Scrima"'
Autor:
Danilo Swann Matassa, Daniela Criscuolo, Rosario Avolio, Ilenia Agliarulo, Daniela Sarnataro, Consiglia Pacelli, Rosella Scrima, Alessandra Colamatteo, Giuseppe Matarese, Nazzareno Capitanio, Matteo Landriscina, Franca Esposito
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-18 (2022)
Abstract Background Metabolic reprogramming is an important issue in tumor biology. A recently-identified actor in this regard is the molecular chaperone TRAP1, that is considered an oncogene in several cancers for its high expression but an oncosupp
Externí odkaz:
https://doaj.org/article/a508672b12454c2387d8c9dd1905a580
Autor:
Rosella Scrima, Francesca Agriesti, Consiglia Pacelli, Claudia Piccoli, Pietro Pucci, Angela Amoresano, Olga Cela, Luigi Nappi, Tiziana Tataranni, Giorgio Mori, Pietro Formisano, Nazzareno Capitanio
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background The metabolic phenotype of stem cells is increasingly recognized as a hallmark of their pluripotency with mitochondrial and oxygen-related metabolism playing a not completely defined role in this context. In a previous study, we r
Externí odkaz:
https://doaj.org/article/d162b7c83d7241e4895476e9887baea2
Autor:
Luise Fuhr, Rukeia El-Athman, Rosella Scrima, Olga Cela, Annalucia Carbone, Henning Knoop, Yin Li, Karen Hoffmann, Mikko O. Laukkanen, Francesco Corcione, Ralf Steuer, Thomas F. Meyer, Gianluigi Mazzoccoli, Nazzareno Capitanio, Angela Relógio
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 105-121 (2018)
An endogenous molecular clockwork drives various cellular pathways including metabolism and the cell cycle. Its dysregulation is able to prompt pathological phenotypes including cancer. Besides dramatic metabolic alterations, cancer cells display sev
Externí odkaz:
https://doaj.org/article/ef1dbb151a5a449aa1c455cb4bcb8751
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Chronic hepatitis C is characterized by metabolic disorders and by a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that can in the long term lead to liver cirrhosis and hepatocellular carcinoma.
Externí odkaz:
https://doaj.org/article/f9cd3f93c657429999eacf906b701859
Autor:
Rosella Scrima, Marta Menga, Consiglia Pacelli, Francesca Agriesti, Olga Cela, Claudia Piccoli, Antonella Cotoia, Alessandra De Gregorio, Julia V Gefter, Gilda Cinnella, Nazzareno Capitanio
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188683 (2017)
Targeting metabolism is emerging as a promising therapeutic strategy for modulation of the immune response in human diseases. In the presented study we used the lipopolysaccharide (LPS)-mediated activation of RAW 264.7 macrophage-like cell line as a
Externí odkaz:
https://doaj.org/article/9b4aabeb8b4b4833b9f68e8196fea19e
Autor:
Antonella Cotoia, Rosella Scrima, Julia V Gefter, Claudia Piccoli, Gilda Cinnella, Michele Dambrosio, Mitchell P Fink, Nazzareno Capitanio
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90917 (2014)
The aim of this study was to test the effect of a small volume administration of p-hydroxyphenylpyruvate (pHPP) in a rat model of profound hemorrhagic shock and to assess a possible metabolic mechanism of action of the compound. The results obtained
Externí odkaz:
https://doaj.org/article/30448f891d004ccba49ddb103e7dbb93
Autor:
Maria Teresa Rocchetti, Tiffany Bellanger, Maria Incoronata Trecca, Stephanie Weidmann, Rosella Scrima, Giuseppe Spano, Pasquale Russo, Vittorio Capozzi, Daniela Fiocco
Small heat-shock proteins (sHSP) are ubiquitous ATP-independent chaperones that prevent irreversible aggregation of heat-damaged denaturing proteins. Lactiplantibacillus plantarum is a widespread Gram-positive bacterium with probiotic claims and vast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed6ad612aba772fcf031eb824e21955
https://hdl.handle.net/2434/952099
https://hdl.handle.net/2434/952099
Autor:
Vitalba Ruggieri, Claudia Piccoli, Rosella Scrima, Consiglia Pacelli, Tiziana Tataranni, Cristoforo Pomara, Ilaria Laurenzana, Olga Cela, Francesca Agriesti, Francesco Sessa, Nazzareno Capitanio, Monica Salerno, Carmela Mazzoccoli, Gabriele Sani
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Nandrolone is a testosterone analogue with anabolic properties commonly abused worldwide, recently utilized also as therapeutic agent in chronic diseases, cancer included. Here we investigated the impact of nandrolone on the metabolic phenotype in He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce651ba649248d30f80c62c610469ce0
http://link.springer.com/article/10.1038/s41598-020-58871-1
http://link.springer.com/article/10.1038/s41598-020-58871-1
Autor:
Claudia Piccoli, Massimiliano Chetta, Consiglia Pacelli, Maurizio Margaglione, Nenad Bukvic, Rosella Scrima, Maria Ripoli, Nazzareno Capitanio, Annamaria D'Aprile, Olga Cela, Giovanna D'Andrea
Publikováno v:
Genes
Genes, Vol 12, Iss 1295, p 1295 (2021)
Genes, Vol 12, Iss 1295, p 1295 (2021)
Mitochondria are dynamic organelles undergoing continuous fusion and fission with Drp1, encoded by the DNM1L gene, required for mitochondrial fragmentation. DNM1L dominant pathogenic variants lead to progressive neurological disorders with early exit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98aa736d05218c68bcb271b0e9eaf969
http://europepmc.org/articles/PMC8467311
http://europepmc.org/articles/PMC8467311
Abnormal hemoglobins can have major consequences for tissue delivery of oxygen. Correct diagnosis of hemoglobinopathies with altered oxygen affinity requires a determination of hemoglobin oxygen dissociation curve (ODC), which relates the hemoglobin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d89cff47467fb1aa917bfb7c31d1399