Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Roseline, Guibon"'
Autor:
Céline Ben Hassen, Jorge L. Gutierrez-Pajares, Cyrille Guimaraes, Roseline Guibon, Michelle Pinault, Gaëlle Fromont, Philippe G. Frank
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-17 (2020)
Abstract Background The highest incidence of breast cancer is in the Western world. Several aspects of the Western lifestyle are known risk factors for breast cancer. In particular, previous studies have shown that cholesterol levels can play an impo
Externí odkaz:
https://doaj.org/article/25a5e3bbac0d4ef39e11dbc1ecab5f56
Autor:
Margaux Deynoux, Nicola Sunter, Elfi Ducrocq, Hassan Dakik, Roseline Guibon, Julien Burlaud-Gaillard, Lucie Brisson, Florence Rouleux-Bonnin, Louis-Romée le Nail, Olivier Hérault, Jorge Domenech, Philippe Roingeard, Gaëlle Fromont, Frédéric Mazurier
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0225485 (2020)
Mesenchymal stem cells (MSC)-spheroid models favor maintenance of stemness, ex vivo expansion and transplantation efficacy. Spheroids may also be considered as useful surrogate models of the hematopoietic niche. However, accessibility to primary cell
Externí odkaz:
https://doaj.org/article/fda9bbef845542e0970d32e54e522297
Autor:
Emeline Bon, Virginie Driffort, Frédéric Gradek, Carlos Martinez-Caceres, Monique Anchelin, Pablo Pelegrin, Maria-Luisa Cayuela, Séverine Marionneau-Lambot, Thibauld Oullier, Roseline Guibon, Gaëlle Fromont, Jorge L. Gutierrez-Pajares, Isabelle Domingo, Eric Piver, Alain Moreau, Julien Burlaud-Gaillard, Philippe G. Frank, Stéphan Chevalier, Pierre Besson, Sébastien Roger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
The capacity of cancer cells to migrate is intimately linked to their ability to induce metastasis. Here the authors show that the sodium channel β4 subunit regulates breast cancer cell migration via inhibition of RhoA activation, independently from
Externí odkaz:
https://doaj.org/article/b868edb8e4164085a3574d6fbc6f262e
Autor:
Stéphanie Chadet, Jordan Allard, Lucie Brisson, Osbaldo Lopez-Charcas, Roxane Lemoine, Audrey Heraud, Stéphanie Lerondel, Roseline Guibon, Gaëlle Fromont, Alain Le Pape, Denis Angoulvant, Lin-Hua Jiang, Ruth Murrell-Lagnado, Sébastien Roger
Publikováno v:
Oncogene. 41:2920-2931
Metastatic progression is a major burden for breast cancer patients and is associated with the ability of cancer cells to overcome stressful conditions, such as nutrients deprivation and hypoxia, and to gain invasive properties. Autophagy and epithel
Autor:
Fanny Bery, Sandy Figiel, Sana Kouba, Delphine Fontaine, Maxime Guéguinou, Marie Potier-Cartereau, Christophe Vandier, Roseline Guibon, Franck Bruyère, Gaëlle Fromont, Karine Mahéo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4786 (2020)
Hypoxia is a well-established feature of prostate cancer (PCa) and is associated with disease aggressiveness. The hypoxic microenvironment initiates multiple adaptive responses including epithelial-to-mesenchymal transition (EMT) and a remodeling of
Externí odkaz:
https://doaj.org/article/f90afe28752b4103903b4206b8b7b1cf
Autor:
Maxime Guéguinou, Sajida Ibrahim, Jérôme Bourgeais, Alison Robert, Trayambak Pathak, Xuexin Zhang, David Crottès, Jacques Dupuy, David Ternant, Valérie Monbet, Roseline Guibon, Hector Flores-Romero, Antoine Lefèvre, Stéphanie Lerondel, Alain Le Pape, Jean-François Dumas, Philippe G. Frank, Alban Girault, Romain Chautard, Françoise Guéraud, Ana J. García-Sáez, Mehdi Ouaissi, Patrick Emond, Olivier Sire, Olivier Hérault, Gaëlle Fromont-Hankard, Christophe Vandier, David Tougeron, Mohamed Trebak, William Raoul, Thierry Lecomte
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Colorectal cancer (CRC) is associated with high mortality worldwide and new targets are needed to overcome treatment resistance. Recent evidences highlight a role of the mitochondria calcium homeostasis in the development of CRC. In this context, we
Autor:
Aurélie Chantôme, Karine Mahéo, Mathilde Cancel, Maxime Guéguinou, Fanny Bery, Marie Potier-Cartereau, Franck Bruyère, Roseline Guibon, Gaëlle Fromont, Christophe Vandier
Publikováno v:
Cancers
Volume 13
Issue 12
Cancers, Vol 13, Iss 2947, p 2947 (2021)
Volume 13
Issue 12
Cancers, Vol 13, Iss 2947, p 2947 (2021)
Simple Summary Currently, neuroendocrine prostate cancers remain fatal, so it is crucial to better understand mechanisms of resistance to hormone therapy driving this phenotype. We have shown that Enza, a new generation hormone therapy, promotes pros
Autor:
Laurent Barantin, Isabelle Filipiak, Gaelle Fromont-Hankard, Jean-Philippe Cottier, Roseline Guibon, Sharon Duffy, Mariam Annan, Ana Paula Narata, Kevin Janot, Tiago R. Oliveira, Michael Gilvarry
Publikováno v:
Journal of NeuroInterventional Surgery. 12:181-185
BackgroundThrombus composition has the potential to affect acute ischemic stroke (AIS) treatment.ObjectiveTo evaluate in an in vitro test the correlation of clot composition, especially erythrocytes (red blood cells (RBCs)), with the variation of sig
Autor:
Marie Potier-Cartereau, Gaëlle Fromont, Côme Pasqualin, Karine Mahéo, Roseline Guibon, Fanny Bery, Franck Bruyère, Véronique Maupoil, Christophe Vandier, Sandy Figiel, Isabelle Domingo
Publikováno v:
The American Journal of Pathology. 189:1268-1275
In prostate cancer research, there is a lack of valuable preclinical models. Tumor cell heterogeneity and sensitivity to microenvironment signals, such as hypoxia or extracellular calcium concentration, are difficult to reproduce. Here, we developed
Autor:
Séverine Marionneau-Lambot, Emeline Bon, Stefania Cannone, Sébastien Roger, Thibauld Oullier, Roseline Guibon, Maria Raffaella Greco, Rosa Rubino, Rosa Angela Cardone, Manuel Bernabe-Garcia, Gaëlle Fromont, Maria-Luisa Cayuela, Stephan J. Reshkin, Loredana Ciaccia, Lorenzo Guerra
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:26-37
Metastatic cancer cells are highly plastic for the expression of different tumor phenotype hallmarks and organotropism. This plasticity is highly regulated but the dynamics of the signaling processes orchestrating the shift from one cell phenotype an