Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Rosel Kretschmer-Kazemi Far"'
Autor:
Georg Sczakiel, Bernhard Haubold, Josephine Dubois, Rosel Kretschmer-Kazemi Far, Jacqueline Rueger
Publikováno v:
Oncotarget
Non-invasive clinical diagnostics of bladder cancer is feasible via a set of chemically distinct molecules including macromolecular tumor markers such as polypeptides and nucleic acids. In terms of tumor-related aberrant gene expression, RNA transcri
Autor:
Sarah Willkomm, Andrea Deerberg, Johannes Heidemann, Friedemann Flügge, Janica Meine, Rui Hu, Rosel Kretschmer-Kazemi Far, Tobias Restle
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146814 (2016)
The human TAR RNA-binding protein (hTRBP) and protein activator of protein kinase R (hPACT) are important players in RNA interference (RNAi). Together with hArgonaute2 (hAgo2) and hDicer they have been reported to form the RISC-loading complex (RLC).
Externí odkaz:
https://doaj.org/article/c1a586801642407db8ff9f9de55a292b
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4381, p 4381 (2021)
Volume 13
Issue 17
Cancers, Vol 13, Iss 4381, p 4381 (2021)
Volume 13
Issue 17
Simple Summary Non-invasive tumor diagnosis includes liquid biopsy withdrawn from extracellular and extratissue samples including human urine in which RNA-based markers can be measured by various means. RNA markers include short-chain RNA such as mic
Autor:
Simon Dornseifer, Kirsten Frank, Georg Sczakiel, Janine Liebschwager, Sarah Willkomm, Jens Christian Claussen, Thomas Martinetz, Tobias Restle, Sandra D. Laufer, Foteini Beltsiou, Rosel Kretschmer-Kazemi Far
Publikováno v:
Nucleic Acids Research
The discovery of RNA interference (RNAi) gave rise to the development of new nucleic acid-based technologies as powerful investigational tools and potential therapeutics. Mechanistic key details of RNAi in humans need to be deciphered yet, before suc
Autor:
Andrea Deerberg, Rui Hu, Tobias Restle, Janica Meine, Rosel Kretschmer-Kazemi Far, Sarah Willkomm, Friedemann Flügge, Johannes Heidemann
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146814 (2016)
PLoS ONE
PLoS ONE
The human TAR RNA-binding protein (hTRBP) and protein activator of protein kinase R (hPACT) are important players in RNA interference (RNAi). Together with hArgonaute2 (hAgo2) and hDicer they have been reported to form the RISC-loading complex (RLC).
Autor:
Jürgen Brinckmann, Holger Notbohm, Chimedtseren Batmunkh, Werner Lindenmaier, Rosel Kretschmer-Kazemi Far, Dieter P. Reinhardt, Nico Hunzelmann, Jiang Wu
Publikováno v:
Experimental Cell Research. 312:3485-3494
The pathogenesis of fibrosis, especially involving post-translational modifications of collagen, is poorly understood. Lysyl hydroxylase 2 (long) (LH2 (long)) is thought to play a pivotal role in fibrosis by directing the collagen cross-link pattern.
Autor:
Marc Lemaitre, Ian Robbins, Marita Overhoff, Georg Sczakiel, Rosel Kretschmer-Kazemi Far, Bernard Lebleu, Martina Alken
Publikováno v:
Journal of Molecular Biology. 348:871-881
The efficiency with which small interfering RNAs (siRNAs) down-regulate specific gene expression in living cells is variable and a number of sequence-governed, biochemical parameters of the siRNA duplex have been proposed for the design of an efficie
Autor:
Holger Y. Toschka, Ferdinand Hucho, Joachim C.R. Struck, Volker A. Erdmann, Werner Schröder, Rosel Kretschmer-Kazemi Far
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1050:80-83
The Bacillus subtilis small cytoplasmic RNA (scRNA) is the structural homologue of both the RNA component of the eukaryotic signal recognition particle (SRP) and the Escherichia coli 4.5S RNA, and it can complement the essential function of the latte
Publikováno v:
Chemistrybiodiversity. 2(2)
We propose 2'-C-methylnucleotides as a new class of 2'-modified RNA mimics. These analogues are expected to provide 2'-OH groups capable of reproducing the interactions observed in natural RNA and, due to the presence of the Me group, to possess incr
Publikováno v:
Journal of bacteriology. 188(19)
Bacterial RNase P is composed of an RNA subunit and a single protein subunit (encoded by the rnpB and rnpA genes, respectively). We constructed Bacillus subtilis mutant strains that conditionally express the RNase P protein under control of the xylos