Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rosel Blasig"'
Autor:
Jeremy Tsung-Chieh Chen, Xiawei Hu, Isabel U.C. Otto, Christina Schürger, Bruno Rogalla von Bieberstein, Kathrin Doppler, Susanne M. Krug, Mohammed K. Hankir, Rosel Blasig, Claudia Sommer, Alexander Brack, Ingolf E. Blasig, Heike L. Rittner
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106246- (2023)
Background: The blood-nerve and myelin barrier shield peripheral neurons and their axons. These barriers are sealed by tight junction proteins, which control the passage of potentially noxious molecules including proinflammatory cytokines via paracel
Externí odkaz:
https://doaj.org/article/555600b0ece440f998ec1507add56ceb
Autor:
Ningjing Lei, Yanru Cheng, Jiajia Wan, Rosel Blasig, Anqi Li, Yueyue Bai, Reiner F. Haseloff, Ingolf E. Blasig, Linyu Zhu, Zhihai Qin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Claudin-3 is a tight junction protein that has often been associated with the progression and metastasis of various tumors. Here, the role of claudin-3 in tumor-induced lymphangiogenesis is investigated. We found an increased lymphangiogenes
Externí odkaz:
https://doaj.org/article/59ed644337784e4193efb81bc0cb0487
Autor:
Hong Cao, Chen Ni, Le Han, Ruoqi Wang, Rosel Blasig, Reiner Haseloff, Yue Qin, Jie Lan, Xiaohan Lou, Pan Ma, Xiaohan Yao, Linlin Wang, Fei Wang, Linyu Zhu, Ningjing Lei, Ingolf E. Blasig, Zhihai Qin
Publikováno v:
Cancer Research. 82:2472-2484
Migration of myeloid-derived suppressor cells (MDSC) out of the circulation, across vascular walls, and into tumor is crucial for their immunosuppressive activity. A deeper understanding of critical junctional molecules and the regulatory mechanisms
Autor:
Zhihai Qin, Ingolf E. Blasig, Ningjing Lei, Linyu Zhu, Fei Wang, Linlin Wang, Xiaohan Yao, Pan Ma, Xiaohan Lou, Jie Lan, Yue Qin, Reiner Haseloff, Rosel Blasig, Ruoqi Wang, Le Han, Chen Ni, Hong Cao
Migration of myeloid-derived suppressor cells (MDSC) out of the circulation, across vascular walls, and into tumor is crucial for their immunosuppressive activity. A deeper understanding of critical junctional molecules and the regulatory mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab5f44f1f164c7a5d9b89f6a9cc6ff1
https://doi.org/10.1158/0008-5472.c.6514082.v1
https://doi.org/10.1158/0008-5472.c.6514082.v1
Autor:
Zhihai Qin, Ingolf E. Blasig, Ningjing Lei, Linyu Zhu, Fei Wang, Linlin Wang, Xiaohan Yao, Pan Ma, Xiaohan Lou, Jie Lan, Yue Qin, Reiner Haseloff, Rosel Blasig, Ruoqi Wang, Le Han, Chen Ni, Hong Cao
Supplementary Table from Claudin-12 Deficiency Inhibits Tumor Growth by Impairing Transendothelial Migration of Myeloid-Derived Suppressor Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ee46717ff1ee71c4b7d55b9f95fad0
https://doi.org/10.1158/0008-5472.22432163
https://doi.org/10.1158/0008-5472.22432163
Autor:
Ingolf E. Blasig, Philipp Berndt, Rosel Blasig, Sophie Dithmer, Reiner F. Haseloff, Hartwig Wolburg, Lars Winkler, Valentina Rausch, Olga Breitkreuz-Korff, Anje Sporbert, André Rex, Jimmi Cording, Matthias Richter
Publikováno v:
Cellular and Molecular Life Sciences. 76:1987-2002
At the blood-brain barrier (BBB), claudin (Cldn)-5 is thought to be the dominant tight junction (TJ) protein, with minor contributions from Cldn3 and -12, and occludin. However, the BBB appears ultrastructurally normal in Cldn5 knock-out mice, sugges
Autor:
Hartwig Wolburg, Dmytro Puchkov, Stefan Liebner, Ingolf E. Blasig, Rosel Blasig, Philipp Berndt, Kavi Devraj, Sophie Dithmer, Anuska V. Andjelkovic, Olga Breitkreuz-Korff, Reiner F. Haseloff, Hans Christian Cederberg Helms, André Rex, Zhihai Qin, Mehmet Kaya, Lars Winkler
Publikováno v:
J Cereb Blood Flow Metab
The outcome of stroke is greatly influenced by the state of the blood–brain barrier (BBB). The BBB endothelium is sealed paracellularly by tight junction (TJ) proteins, i.e., claudins (Cldns) and the redox regulator occludin. Functions of Cldn3 and
Autor:
Thoralf Niendorf, Ingolf E. Blasig, Nora Gehne, Andreas Pohlmann, Petra Fallier-Becker, Mária A. Deli, Lars Winkler, Christian Staat, Fruzsina R. Walter, Min Chi Ku, Ágnes Kittel, Rosel Blasig, Reiner F. Haseloff, Szilvia Veszelka, Sophie Dithmer, Carolin Müller
Publikováno v:
Annals of the New York Academy of Sciences. 1397:169-184
The blood–brain barrier (BBB) formed by the microvascular endothelium limits cerebral drug delivery. The paraendothelial cleft is sealed by tight junctions (TJs) with a major contribution from claudin-5, which we selected as a target to modulate BB
Autor:
Mohammed K Hankir, Rosel Blasig, Petra Fallier-Becker, Xiawei Hu, Lars Winkler, Claudia Sommer, Alexander Brack, Katrin Doppler, Heike L. Rittner, Ingolf E. Blasig, Jeremy Tsung-Chieh Chen, Sophie Dithmer, Ann-Kristin Reinhold, Olga Breitkreuz-Korff, Dorothee Guenzel, Isabel Uc Otto, Joachim Schwabe
Peripheral nerves and their axons are shielded by the blood-nerve and the myelin barrier. Understanding of how these barriers impact nociception is limited, particularly in neuropathy. Here, we identified a regulatory axis of the tight junction prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb4f141614c6f836ab41d23aa602012
Autor:
Sophie, Dithmer, Christian, Staat, Carolin, Müller, Min-Chi, Ku, Andreas, Pohlmann, Thoralf, Niendorf, Nora, Gehne, Petra, Fallier-Becker, Ágnes, Kittel, Fruzsina R, Walter, Szilvia, Veszelka, Maria A, Deli, Rosel, Blasig, Reiner F, Haseloff, Ingolf E, Blasig, Lars, Winkler
Publikováno v:
Annals of the New York Academy of Sciences. 1397(1)
The blood-brain barrier (BBB) formed by the microvascular endothelium limits cerebral drug delivery. The paraendothelial cleft is sealed by tight junctions (TJs) with a major contribution from claudin-5, which we selected as a target to modulate BBB