Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Roseann F. Titcombe"'
Autor:
Roseann F. Titcombe, Seonil Kim, Edward B. Ziff, Latika Khatri, Ottavio Arancio, Hong Zhang, Hiwot K. Girma, Franz Hofmann
Publikováno v:
Proceedings of the National Academy of Sciences. 112:3122-3127
Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872e3fddb3928c0a90b1e55965b5f158
https://doi.org/10.1073/pnas.1417498112
https://doi.org/10.1073/pnas.1417498112
Autor:
Roseann F. Titcombe, Edward B. Ziff, Shannon O. Antoine, Sinedu Abera, David S. Tukey, Loren M. DeVito, Charles A. Hoeffer, Sarah A. Vunck, Yoon Choi, Natasha N. Tirko, Franz Hofmann, Charlotte M. Wincott
Publikováno v:
Neurobiology of Learning and Memory. 114:32-39
Neuronal activity regulates AMPA receptor trafficking, a process that mediates changes in synaptic strength, a key component of learning and memory. This form of plasticity may be induced by stimulation of the NMDA receptor which, among its activitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b08d08efddd244f6df0255fc02310d
https://doi.org/10.1016/j.nlm.2014.04.007
https://doi.org/10.1016/j.nlm.2014.04.007
Autor:
Kenneth D. Carr, Carlo B. Guarini, Megna Khatri, Soledad Cabeza de Vaca, Duo Xu, Charlotte M. Wincott, Jainne M. Ferreira, Jing Wang, Julian K. Horwitz, Robert C. Froemke, Yossef Goffer, Edward B. Ziff, Roseann F. Titcombe, Ipe Ninan, Salvatore Incontro, Dave S. Marzan, Latika Khatri, Chiye Aoki, Shahana S. Mahajan, Shannon O. Antoine, James A. D’amour, David S. Tukey, Diana T. Hartner
Publikováno v:
The Journal of Neuroscience. 33:6123-6132
The mechanisms by which natural rewards such as sugar affect synaptic transmission and behavior are largely unexplored. Here, we investigate regulation of nucleus accumbens synapses by sucrose intake. Previous studies have shown that AMPA receptor (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9478d35247bee289e5d233e5e3dd2843
https://doi.org/10.1523/jneurosci.4806-12.2013
https://doi.org/10.1523/jneurosci.4806-12.2013
Autor:
Edward B. Ziff, Seonil Kim, Franz Hofmann, Charles A. Hoeffer, David S. Tukey, Loren M. DeVito, Hiwot K. Girma, Roseann F. Titcombe, Joseph Pick, Charlotte M. Wincott
Activity-dependent trafficking of AMPA receptors to synapses regulates synaptic strength. Activation of the NMDA receptor induces several second messenger pathways that contribute to receptor trafficking-dependent plasticity, including the NO pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145b9853d81ec3922b8f867f0dd8598a
https://europepmc.org/articles/PMC3541678/
https://europepmc.org/articles/PMC3541678/
Autor:
Elsa D. Garcin-Hosfield, David S. Tukey, Edward B. Ziff, Elizabeth D. Getzoff, Latika Khatri, Charu Misra, Gerald A. Rameau, Roseann F. Titcombe
Postsynaptic nitric oxide (NO) production affects synaptic plasticity and neuronal cell death. Ca2+fluxes through the NMDA receptor (NMDAR) stimulate the production of NO by neuronal nitric oxide synthase (nNOS). However, the mechanisms by which nNOS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f111a811983f1d5c5d91b68ae0097b
https://europepmc.org/articles/PMC6672118/
https://europepmc.org/articles/PMC6672118/