The FGF/FGFR/c-Myc axis as a promising therapeutic target in multiple myeloma.

Autor: Giacomini, Arianna¹ (AUTHOR) arianna.giacomini@unibs.it, Taranto, Sara² (AUTHOR), Gazzaroli, Giorgia¹ (AUTHOR), Faletti, Jessica¹ (AUTHOR), Capoferri, Davide¹ (AUTHOR), Marcheselli, Raffaella² (AUTHOR), Sciumè, Margherita² (AUTHOR), Presta, Marco¹ (AUTHOR), Sacco, Antonio² (AUTHOR), Roccaro, Aldo M.² (AUTHOR) aldomaria.roccaro@asst-spedalicivili.it

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 11/1/2024, Vol. 43 Issue 1, p1-17. 17p.

Targeting mTOR and survivin concurrently potentiates radiation therapy in renal cell carcinoma by suppressing DNA damage repair and amplifying mitotic catastrophe.

Autor: Rachamala, Hari K.¹ (AUTHOR), Madamsetty, Vijay S.^1,2 (AUTHOR), Angom, Ramcharan S.¹ (AUTHOR), Nakka, Naga M.¹ (AUTHOR), Dutta, Shamit Kumar¹ (AUTHOR), Wang, Enfeng¹ (AUTHOR), Mukhopadhyay, Debabrata¹ (AUTHOR) mukhopadhyay.debabrata@mayo.edu, Pal, Krishnendu¹ (AUTHOR) pal.krishnendu@mayo.edu

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 6/6/2024, Vol. 43, p1-17. 17p.

Transgenic mouse model of IgM ⁺ lymphoproliferative disease mimicking Waldenström macroglobulinemia.

Autor: Tompkins VS; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Sompallae R; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.; Bioinformatics Division, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Rosean TR; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Walsh S; Department of Radiology, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Acevedo M; Department of Radiology, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Kovalchuk AL; Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Han SS; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Jing X; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Holman C; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Rehg JE; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA., Herms S; International Waldenstrom's Macroglobulinemia Foundation, Sarasota, FL, USA., Sunderland JS; Department of Radiology, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA., Morse HC; Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Janz S; Department of Pathology, Iowa Institute of Human Genetics, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.

Publikováno v: Blood cancer journal [Blood Cancer J] 2016 Nov 04; Vol. 6 (11), pp. e488. Date of Electronic Publication: 2016 Nov 04.

KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice.

Autor: Rosean TR; Department of Pathology, University of Iowa (UI) Carver College of Medicine, Iowa City, IA, USA., Holman CJ; Department of Pathology, University of Iowa (UI) Carver College of Medicine, Iowa City, IA, USA., Tompkins VS; Department of Pathology, University of Iowa (UI) Carver College of Medicine, Iowa City, IA, USA., Jing X; Department of Pathology, University of Iowa (UI) Carver College of Medicine, Iowa City, IA, USA., Krasowski MD; Department of Pathology, University of Iowa (UI) Carver College of Medicine, Iowa City, IA, USA., Rose-John S; Institute of Biochemistry, Christian-Albrechts-University, Kiel, Germany., Janz S; Department of Pathology, University of Iowa (UI) Carver College of Medicine, Iowa City, IA, USA.; UI Holden Comprehensive Cancer Center, Iowa City, IA, USA.

Publikováno v: Blood cancer journal [Blood Cancer J] 2016 Feb 26; Vol. 6, pp. e398. Date of Electronic Publication: 2016 Feb 26.

NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas.

Autor: Reed SM; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America; Medical Scientist Training Program, University of Iowa, Iowa City, Iowa, United States of America., Hagen J; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America., Muniz VP; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America; Molecular and Cellular Biology Program, University of Iowa, Iowa City, Iowa, United States of America., Rosean TR; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America., Borcherding N; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Sciegienka S; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America., Goeken JA; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Naumann PW; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Zhang W; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Tompkins VS; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Janz S; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, Iowa, United States of America; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Meyerholz DK; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America., Quelle DE; Department of Pharmacology, University of Iowa, Iowa City, Iowa, United States of America; Medical Scientist Training Program, University of Iowa, Iowa City, Iowa, United States of America; Molecular and Cellular Biology Program, University of Iowa, Iowa City, Iowa, United States of America; Department of Pathology, University of Iowa, Iowa City, Iowa, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Nov 13; Vol. 9 (11), pp. e112126. Date of Electronic Publication: 2014 Nov 13 (Print Publication: 2014).