Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rose-Marie Goebbels"'
Autor:
Sophie Vériter, Najima Aouassar, Gwen Beaurin, Rose-Marie Goebbels, Pierre Gianello, Denis Dufrane Ph.D.
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Pig islets demonstrate significantly lower insulin secretion after glucose stimulation than human islets (stimulation index of ~12 vs. 2 for glucose 1 and 15 mM, respectively) due to a major difference in β- and α-cell composition in islets (60% an
Externí odkaz:
https://doaj.org/article/a69f36fff85a4b68b319bbd860526616
Autor:
Xavier Caignet, Bénédicte F. Jordan, Olivier Feron, Patrice D. Cani, Stefania Acciardo, Rose-Marie Goebbels, Lionel Mignion, Cyril Corbet, Florian Gourgue, Sandra Schmitz, Jean-Pascal Machiels, Caroline Bouzin, Nicolas Joudiou
Publikováno v:
Clinical cancer research, Vol. 15, no. 26(8), p. 1932-1943 (2020)
Purpose: Optimal head and neck squamous cell carcinoma (HNSCC) patient selection for anti–EGFR-based therapy remains an unmet need since only a minority of patients derive long-term benefit from cetuximab treatment. We assessed the ability of state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff57f618e6344b5d623dad60e8687b9
https://hdl.handle.net/2078.1/224027
https://hdl.handle.net/2078.1/224027
Autor:
Bénédicte F. Jordan, Els Hermans, Xavier Caignet, Sandra Schmitz, Thierry Duprez, Rose-Marie Goebbels, Nicolas Michoux, Frédéric Amant, Vincent Grégoire, Marie-Aline Neveu, Jean-Pascal Machiels, Renaud Lhommel, Anne Bol, Lionel Mignion
Publikováno v:
Oncotarget
Oncotarget, Vol. 9, no. 47, p. 28572-28585 (2018)
Oncotarget, Vol. 9, no. 47, p. 28572-28585 (2018)
We investigated changes on 2'-deoxy-2'-[18F]fluoro-D-glucose positron emission tomography (18FDG-PET), diffusion-weighted magnetic resonance imaging (DW-MRI), and choline spectroscopy as early markers of cetuximab activity in squamous cell carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786a332e741b217103b1d955aefc1d00
http://europepmc.org/articles/PMC6033354
http://europepmc.org/articles/PMC6033354
Autor:
Antonella Mendola, Xavier Caignet, Rose-Marie Goebbels, Nisha Limaye, Jean-Pascal Machiels, Raphaël Helaers, Kyril Wittouck, Jérôme Ambroise, Cédric van Marcke, Miikka Vikkula, R. Galot
Publikováno v:
Oral oncology, Vol. 104, p. 104631 (2020)
The molecular landscape of head and neck squamous cell carcinoma (HNSCC) harbors potentially actionable genomic alterations. We aimed to study the utility of liquid biopsy to (i) characterize the mutational landscape of recurrent/metastatic HNSCC usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa51affddd2256c2832fc74eed7056ec
https://doi.org/10.1016/j.oraloncology.2020.104631
https://doi.org/10.1016/j.oraloncology.2020.104631
Autor:
Nisha Limaye, K. Wittouck, Miikka Vikkula, C. Van Marcke de Lummen, Raphaël Helaers, Antonella Mendola, Xavier Caignet, Jérôme Ambroise, J.-P. Machiels, R. Galot, Rose-Marie Goebbels
Publikováno v:
Annals of Oncology. 30:v468-v469
Background Circulating tumor DNA (ctDNA) is a minimally-invasive technique to profile the tumor genome in different cancers but is still underexplored in squamous cell carcinoma of the head and neck (SCCHN). Our aim was to study the relevance of muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4e7eb88be2ebdbdcb037040b4e6f31
https://doi.org/10.1093/annonc/mdz252.049
https://doi.org/10.1093/annonc/mdz252.049
Publikováno v:
Journal of Pediatric Surgery, (2016)
BACKGROUND: Reconstruction of muscle defects remains a challenge. Our work assessed the potential of an engineered construct made of a human acellular collagen matrix (HACM) seeded with porcine mesenchymal stem cells (MSCs) to reconstruct abdominal w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a6204bb818dfdb87d96446dc830f88
https://pubmed.ncbi.nlm.nih.gov/27939203
https://pubmed.ncbi.nlm.nih.gov/27939203
Publikováno v:
Transplantation. 90:1054-1062
BACKGROUND.: This study assessed the capacity of alginate-encapsulated islets to reverse diabetes in a pig-to-primate model. METHODS.: Adult pig islets were encapsulated in microcapsules implanted under the kidney capsule (n=4) or in a subcutaneous m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f87b3ed477ab19c82775c8ba4646895
https://doi.org/10.1097/tp.0b013e3181f6e267
https://doi.org/10.1097/tp.0b013e3181f6e267
Publikováno v:
Xenotransplantation. 17:449-459
BACKGROUND: We developed a composite scoring system to accurately assess pig islet function in pre-clinical primate studies. METHODS: Two scoring methods that have been clinically validated in human islet allotransplantation were tested in six non-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc0ca2fd2946aa9931e38d0d62104921
https://doi.org/10.1111/j.1399-3089.2010.00612.x
https://doi.org/10.1111/j.1399-3089.2010.00612.x
Autor:
Julien Mergen, Philippe Levêque, Sophie Vériter, Bénédicte F. Jordan, Rose-Marie Goebbels, Bernard Gallez, Charles Grégoire, Pierre Gianello, Najima Aouassar, Denis Dufrane
Publikováno v:
Tissue Engineering Part A. 16:1503-1513
Islet encapsulation requires several properties including (1) biocompatibility, (2) immunoprotection, and (3) oxygen diffusion for islet survival and diabetes correction. New chemical alginates were tested in vivo and compared with traditional high-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64494750d8eb41ed937b1571a744a3c
https://doi.org/10.1089/ten.tea.2009.0286
https://doi.org/10.1089/ten.tea.2009.0286
Autor:
Elisa Bigare, S. Fawzi-Grancher, Rose-Marie Goebbels, Pierre Gianello, Christian Delloye, Olivier Cornu, Denis Dufrane
Publikováno v:
Journal of Materials Science: Materials in Medicine. 20:1709-1720
This work investigates the impact of chemical and physical treatments on biocompatibility for human bone/tendon tissues. Nontreated and treated tissues were compared. In vitro testing assessed indirect and direct cytotoxicity. Tissues were subcutaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ea7749f6ca4e7fc953f10d24e3e347
https://doi.org/10.1007/s10856-009-3726-0
https://doi.org/10.1007/s10856-009-3726-0