Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rose-Marie Catalioto"'
Autor:
Rose-Marie Catalioto, Claudio Valenti, Francesca Bellucci, Cecilia Cialdai, Maria Altamura, Laura Digilio, Andrea Ugo Enrico Pellacani, Stefania Meini
Publikováno v:
Heliyon, Vol 7, Iss 6, Pp e07314- (2021)
Achieving durable protective immunity following vaccination is dependent on many factors, including vaccine composition and antigen dose, and it has been investigated for various types of vaccines. Aim of the present study was to investigate the over
Externí odkaz:
https://doaj.org/article/b3af71dcfd1d4680b139018984c7ebff
Autor:
Stefania Meini, Cecilia Cialdai, Maria Altamura, Francesca Bellucci, Claudio Valenti, Andrea Ugo Enrico Pellacani, Laura Digilio, Rose-Marie Catalioto
Publikováno v:
Heliyon, Vol 7, Iss 6, Pp e07314-(2021)
Heliyon
Heliyon
Achieving durable protective immunity following vaccination is dependent on many factors, including vaccine composition and antigen dose, and it has been investigated for various types of vaccines. Aim of the present study was to investigate the over
Publikováno v:
Biochemical Pharmacology. 97:189-202
Kallikrein, kininogen and kinin receptors are present in human ocular tissues including the retinal pigment epithelium (RPE), suggesting a possible role of bradykinin (BK) in physiological and/or pathological conditions. To test this hypothesis, kini
Publikováno v:
Biochemical Pharmacology. 86:508-520
Obesity and adipose tissue contribute to local and systemic inflammation. However the role of the inflammatory mediator bradykinin (BK) in this context is not known. We therefore evaluated the effect of BK on adipokines secretion in human preadipocyt
Autor:
Marina Porcelloni, Elena Marastoni, Maria Altamura, Rose-Marie Catalioto, Sandro Giuliani, Carlo Alberto Maggi, Sandro Mauro, Stefania Meini, Cristina Rossi, Piero D’Andrea, Alessandro Ettorre, Daniela Fattori
Publikováno v:
Journal of Medicinal Chemistry. 53:4148-4165
As part of a project aimed at the identification of a series of small, orally available antagonists for the hNK(2) receptor, starting from one of our capped dipeptide libraries, we succeeded in the chemical optimization of the first identified leads,
Autor:
Carla Festa, Sandro Giuliani, Rose-Marie Catalioto, Antonio Triolo, Maria Altamura, Carlo Alberto Maggi
Publikováno v:
Journal of Pharmaceutical Sciences. 98:713-727
The present study investigates the effects of ethanol and hydrogen peroxide (H 2 O 2 ) on the barrier function and prostaglandin E 2 (PGE 2 ) release in differentiated Caco‐2 cells. Epithelial barrier integrity was estimated by measuring transepith
Autor:
Sandro Giuliani, Maria Altamura, Carlo Alberto Maggi, Antonio Guidi, Rose-Marie Catalioto, Stefania Meini, Alessandro Giolitti, Danilo Giannotti, Nicholas J. S. Harmat, Alessandro Lecci, Franco Pasqui, and Antonio Triolo, Rossano Nannicini, Manuela Tramontana, Valentina Fedi
Publikováno v:
Journal of Medicinal Chemistry. 50:4793-4807
Starting from 1 (MEN14268), a selective tachykinin NK2 receptor antagonist with an interesting in vitro pharmacological profile, a family of numerous antagonists was obtained through an optimization process focused on iterated structural modification
Autor:
Claudio Catalani, Claudio Valenti, Cecilia Cialdai, Carlo Alberto Maggi, Manuela Tramontana, Stefania Meini, Sandro Giuliani, Rose-Marie Catalioto, Maria Altamura, Alessandro Lecci, Riccardo Patacchini
Publikováno v:
European Journal of Pharmacology. 549:140-148
The pharmacological profile of MEN15596 or (6-methyl-benzo[b]thiophene-2-carboxylic acid [1-(2-phenyl-1R-{[1-(tetrahydropyran-4-ylmethyl)-piperidin-4-ylmethyl]-carbamoyl}-ethylcarbamoyl)-cyclopentyl]-amide), a novel potent and selective tachykinin NK
Autor:
Luigi Rotondaro, Carlo Alberto Maggi, Stefania Meini, Rose-Marie Catalioto, Alessandro Giolitti, Sandro Giuliani, Angela Faiella, Francesca Bellucci, Laura Quartara, Claudio Catalani, Francisco M. Pinto, María L. Candenas
Publikováno v:
European Journal of Pharmacology. 499:229-238
In the present study, we have investigated, by binding and functional experiments, the pharmacological profile of a new human tachykinin NK(2) receptor splice variant named beta isoform. Neurokinin A, nepadutant, SR48968 [(S)-N-methyl-N[4-(4-acetylam
Autor:
Alessandro Lecci, Sandro Giuliani, Rose-Marie Catalioto, Carlo Alberto Maggi, Francesca Carini, Paolo Santicioli, Manuela Tramontana
Publikováno v:
European Journal of Pharmacology. 439:149-158
We have studied the effect of selective tachykinin NK 1 and NK 2 receptor antagonists on airway hyperreactivity to acetylcholine and increase of inflammatory cells on bronchoalveolar lavage fluid induced by sephadex beads (20 mg/kg, i.v.) in guinea p