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Akademický článek

Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial.

Autor: Joel L Johnson, Yi Shi, Rose Snipes, Salim Janmohamed, Timothy E Rolfe, Bill Davis, Anthony Postle, Colin H Macphee

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89034 (2014)

The aim of this study was to assess the effects of darapladib, a selective oral investigational lipoprotein-associated phospholipase A2 inhibitor, on both plasma and plaque lipoprotein-associated phospholipase A2 activity.Patients undergoing elective

Externí odkaz: https://doaj.org/article/4f6a0d57773b45c8a3130070c50f8fba

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Phase 2 multiple-dose study of an FcRn inhibitor, rozanolixizumab, in patients with primary immune thrombocytopenia

Autor: Isidro Jarque, Nichola Cooper, Juan Ke, James B. Bussel, Rose Snipes, Stephen Jolles, Maciej Kaźmierczak, Grant Langdon, Tadeusz Robak, Jacek Treliński, Franz Woltering, Vasile Musteata, Peter Kiessling, Ute Massow

Publikováno v: Blood Adv
Blood Advances
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Primary immune thrombocytopenia (ITP) is a predominantly immunoglobulin G (IgG)-autoantibody-mediated disease characterized by isolated thrombocytopenia. Rozanolixizumab, a subcutaneously infused humanized monoclonal anti-neonatal Fc receptor (FcRn)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bc337c5180414ce07cb7ca49b17b61
https://pubmed.ncbi.nlm.nih.gov/32886753

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Rozanolixizumab, an Anti-FcRn Antibody: Final Results from a Phase II, Multiple-Dose Study in Patients with Primary Immune Thrombocytopenia

Autor: Jacek Treliński, Ute Massow, Franz Woltering, James B. Bussel, Peter Kiessling, Tadeusz Robak, Juan Ke, Stephen Jolles, Maciej Kaźmierczak, Isidro Jarque, Rose Snipes, Birgit Haier, Vasile Musteata, Grant Langdon, Nichola Cooper

Publikováno v: Blood. 134:897-897

Introduction Rozanolixizumab targets the human neonatal Fc receptor (FcRn). By blocking IgG recycling, this first-in-class subcutaneously (SC) infused monoclonal antibody aims to improve the course of immunoglobulin G (IgG)-mediated autoimmune diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f307bef8051be736ea715f87e54517b
https://doi.org/10.1182/blood-2019-129839

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Long-term up to 24-month efficacy and safety of concomitant prescription omega-3-acid ethyl esters and simvastatin in hypertriglyceridemic patients

Autor: Ralph T. Doyle, James M. McKenney, Harold E. Bays, Evan A. Stein, Rosemary Schroyer, Rose Snipes, Amy M Meadowcroft, Kevin C. Maki

Publikováno v: Current Medical Research and Opinion. 26:907-915

Assess the long-term efficacy and safety of prescription omega-3-acid ethyl esters (P-OM3) coadministered with simvastatin in an extension of the Combination of Prescription Omega-3 Plus Simvastatin (COMBOS) trial.COMBOS included hypertriglyceridemic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f977007d66038d9a50a102ccb507bbc
https://doi.org/10.1185/03007991003645318

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Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial

Autor: Salim Janmohamed, Bill Davis, Colin H. Macphee, Anthony D. Postle, Rose Snipes, Joel L. Johnson, Yi Shi, Timothy E. Rolfe

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89034 (2014)
PLoS ONE

BackgroundThe aim of this study was to assess the effects of darapladib, a selective oral investigational lipoprotein-associated phospholipase A2 inhibitor, on both plasma and plaque lipoprotein-associated phospholipase A2 activity.MethodsPatients un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d2a2f2921f420a55ed5205db9334ae
http://europepmc.org/articles/PMC3930668?pdf=render

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Intracranial hemorrhage after coronary thrombolysis with tissue plasminogen activator

Autor: Rose Snipes, Judith K. Little John, Michael S. Pessin, Justin A. Zivin, Carlos S. Kase, Gregory J. del Zoppo, Anthony J. Furlan, Jill W. Buckley

Publikováno v: The American journal of medicine. 92(4)

We analyzed the clinical, laboratory, and radiologic data in nine patients who sustained an intracranial hemorrhage (ICH) after receiving intravenous recombinant tissue plasminogen activator (rt-PA) and heparin for treatment of acute myocardial infar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec85837b188a5f8f8b1fbaae77fe13f
https://pubmed.ncbi.nlm.nih.gov/1558085

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