Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rose Pedretti"'
Autor:
Binh An Nguyen, Virender Singh, Shumaila Afrin, Preeti Singh, Maja Pekala, Yasmin Ahmed, Rose Pedretti, Jacob Canepa, Andrew Lemoff, Barbara Kluve-Beckerman, Pawel M. Wydorski, Farzeen Chhapra, Lorena Saelices
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract ATTR amyloidosis results from the conversion of transthyretin into amyloid fibrils that deposit in tissues causing organ failure and death. This conversion is facilitated by mutations in ATTRv amyloidosis, or aging in ATTRwt amyloidosis. ATT
Externí odkaz:
https://doaj.org/article/8fc633682aa74991a520534aaeef48a7
Autor:
Binh An Nguyen, Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed, Rose Pedretti, Maria del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O. Cabrera Hernandez, Siddharth Kumar, Andrew Lemoff, Roman Gonzalez-Prieto, Michael R. Sawaya, David S. Eisenberg, Merrill Douglas Benson, Lorena Saelices
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract ATTR amyloidosis is caused by the deposition of transthyretin in the form of amyloid fibrils in virtually every organ of the body, including the heart. This systemic deposition leads to a phenotypic variability that has not been molecularly
Externí odkaz:
https://doaj.org/article/60a20b40007f4acdaf11442427648360
Autor:
Caleb J. Hood, Nicholas S. Hendren, Rose Pedretti, Lori R. Roth, Lorena Saelices, Justin L. Grodin
Publikováno v:
Current Heart Failure Reports. 19:356-363
Autor:
Aaron T. Balana, Anne-Laure Mahul-Mellier, Binh A Nguyen, Mian Horvath, Afraah Javed, Eldon R. Hard, Yllza Jasiqi, Preeti Singh, Shumaila Afrin, Rose Pedretti, Virender Singh, Virginia M.-Y. Lee, Kelvin C. Luk, Lorena Saelices, Hilal A. Lashuel, Matthew R. Pratt
Publikováno v:
bioRxiv
The process of amyloid fibril formation remains one of the primary targets for developing diagnostics and treatments for several neurodegenerative diseases (NDDs). Amyloid-forming proteins such α-Synuclein and Tau, which are implicated in the pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9a9ba932fcb45cc42feb6f11579b5d
https://doi.org/10.1101/2023.03.07.531573
https://doi.org/10.1101/2023.03.07.531573
Autor:
Binh An Nguyen, Shumaila Afrin, Virender Singh, Yasmin Ahmed, Rose Pedretti, Maria del Carmen Fernandez-Ramirez, Merrill Douglas Benson, Michael Sawaya, Preeti Singh, Qin Cao, David Boyer, Alexander Pope, Pawel Wydorski, Siddharth Kumar, Farzeen Chhapra, David Eisenberg, Lorena Saelices
The deposition of amyloidogenic transthyretin (ATTR) in ATTR amyloidosis leads to an unexplained variety of clinical phenotypes, including cardiomyopathy. In brain amyloid conditions, there is an apparent association between the clinical phenotype an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81647da97a671b17e6c27971afdccf4c
https://doi.org/10.1101/2022.06.21.496949
https://doi.org/10.1101/2022.06.21.496949