Biomedical knowledge graph-optimized prompt generation for large language models.

Autor: Soman K; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States., Rose PW; San Diego Supercomputer Center, University of California, San Diego, CA 92093, United States., Morris JH; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, CA 94158, United States., Akbas RE; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States., Smith B; Institute for Systems Biology, Seattle, WA 98109, United States., Peetoom B; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States., Villouta-Reyes C; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States., Cerono G; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States., Shi Y; Bakar Computational Health Sciences Institute, University of California, San Francisco, CA 94158, United States., Rizk-Jackson A; Bakar Computational Health Sciences Institute, University of California, San Francisco, CA 94158, United States., Israni S; Bakar Computational Health Sciences Institute, University of California, San Francisco, CA 94158, United States., Nelson CA; Mate Bioservices, Inc. Swallowtail Ct., Brisbane, CA 94005, United States., Huang S; Institute for Systems Biology, Seattle, WA 98109, United States., Baranzini SE; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, United States.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2024 Sep 02; Vol. 40 (9).

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The scalable precision medicine open knowledge engine (SPOKE): a massive knowledge graph of biomedical information.

Autor: Morris JH; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, San Francisco, CA 94158, USA., Soman K; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Akbas RE; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Zhou X; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Smith B; Institute for Systems Biology, Seattle, WA 98109, USA., Meng EC; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, San Francisco, CA 94158, USA., Huang CC; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, San Francisco, CA 94158, USA., Cerono G; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Schenk G; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Rizk-Jackson A; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Harroud A; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Sanders L; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA., Costes SV; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA 94035, USA., Bharat K; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Chakraborty A; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Pico AR; Data Science and Biotechnology, Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA., Mardirossian T; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94143-2550, USA., Keiser M; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94143-2550, USA., Tang A; UCSF-UC Berkeley Bioengineering Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA., Hardi J; Stanford Center for Biomedical Informatics Research, Stanford University, Stanford, CA 94305-5479, USA., Shi Y; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Musen M; Stanford Center for Biomedical Informatics Research, Stanford University, Stanford, CA 94305-5479, USA., Israni S; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Huang S; Institute for Systems Biology, Seattle, WA 98109, USA., Rose PW; San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093, USA., Nelson CA; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA., Baranzini SE; Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2023 Feb 03; Vol. 39 (2).

Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial.

Autor: Rose PW (AUTHOR), Harnden A (AUTHOR), Brueggemann AB (AUTHOR), Perera R (AUTHOR), Sheikh A (AUTHOR), Crook D (AUTHOR), Mant D (AUTHOR), Rose, Peter W¹ (AUTHOR), Harnden, Anthony (AUTHOR), Brueggemann, Angela B (AUTHOR), Perera, Rafael (AUTHOR), Sheikh, Aziz (AUTHOR), Crook, Derrick (AUTHOR), Mant, David (AUTHOR)

Publikováno v: Lancet. 7/2/2005, Vol. 366 Issue 9479, p37-43. 7p.

A biomedical open knowledge network harnesses the power of AI to understand deep human biology.

Autor: Baranzini SE; Weill Institute for Neurosciences. Department of Neurology. University of California San Francisco. San Francisco, CA.; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA., Börner K; Department of Intelligent Systems Engineering. Indiana University. Bloomington, IN., Morris J; Department of Pharmaceutical Chemistry. University of California San Francisco. San Francisco, CA., Nelson CA; Weill Institute for Neurosciences. Department of Neurology. University of California San Francisco. San Francisco, CA., Soman K; Weill Institute for Neurosciences. Department of Neurology. University of California San Francisco. San Francisco, CA., Schleimer E; Weill Institute for Neurosciences. Department of Neurology. University of California San Francisco. San Francisco, CA., Keiser M; Department of Pharmaceutical Chemistry. University of California San Francisco. San Francisco, CA.; Institute for Neurodegenerative Diseases. University of California San Francisco. San Francisco, CA., Musen M; Department of Medicine (Biomedical Informatics) and of Biomedical Data Science. Stanford University School of Medicine. Stanford, CA., Pearce R; Center for Applied Scientific Computing (CASC). Lawrence Livermore National Laboratory. Livermore, CA., Reza T; Center for Applied Scientific Computing (CASC). Lawrence Livermore National Laboratory. Livermore, CA., Smith B; Institute for Systems Biology. Seattle, WA., Herr BW 2nd; Department of Intelligent Systems Engineering. Indiana University. Bloomington, IN., Oskotsky B; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA., Rizk-Jackson A; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA., Rankin KP; Weill Institute for Neurosciences. Department of Neurology. University of California San Francisco. San Francisco, CA.; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA., Sanders SJ; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA.; Weill Institute for Neurosciences. Department of Psychiatry and Behavioral Sciences. University of California San Francisco. San Francisco, CA., Bove R; Weill Institute for Neurosciences. Department of Neurology. University of California San Francisco. San Francisco, CA.; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA., Rose PW; San Diego Supercomputer Center. University of California San Diego. La Jolla, CA., Israni S; Bakar Institute for Computational Health Sciences. University of California San Francisco. San Francisco, CA., Huang S; Institute for Systems Biology. Seattle, WA.

Publikováno v: AI magazine [AI Mag] 2022 Spring; Vol. 43 (1), pp. 46-58. Date of Electronic Publication: 2022 Mar 31.