Feasibility and acceptability of undertaking postmortem studies for tuberculosis medical research in a low income country

Autor: Gift Ahimbisibwe, Marjorie Nakibuule, Marvin Martin Ssejoba, David Oyamo, Rose Mulwana, Josephine Nabulime, Febronius Babirye, Musana Abdusalaamu Kizito, Hervé Monka Lekuya, Akello Suzan Adakun, Daisy Nalumansi, Stella Muryasingura, Robert Lukande, Andrew Kyazze, Joseph Baruch Baluku, Irene Andia Biraro, Stephen Cose

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionIf we are to break new ground in difficult-to-treat or difficult-to-vaccinate diseases (such as HIV, malaria, or tuberculosis), we must have a better understanding of the immune system at the site of infection in humans. For tuberculosis

Externí odkaz: https://doaj.org/article/73950710c66b438a9701d1dc3fe8ebd4

Treatment outcomes of drug resistant tuberculosis patients with multiple poor prognostic indicators in Uganda: A countrywide 5-year retrospective study

Autor: Joseph Baruch Baluku, Bridget Nakazibwe, Joshua Naloka, Martin Nabwana, Sarah Mwanja, Rose Mulwana, Mike Sempiira, Sylvia Nassozi, Febronius Babirye, Carol Namugenyi, Samuel Ntambi, Sharon Namiiro, Felix Bongomin, Richard Katuramu, Irene Andia-Biraro, William Worodria

Publikováno v: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 23, Iss , Pp 100221- (2021)

Background: Comorbid conditions and adverse drug events are associated with poor treatment outcomes among patients with drug resistant tuberculosis (DR – TB). This study aimed at determining the treatment outcomes of DR – TB patients with poor pr

Externí odkaz: https://doaj.org/article/2a4b2f3e004f4b05b5fee67c594609cb

Human postmortem studies reveal tissue-specific differences amongst TB-patient groups

Autor: Gift Ahimbisibwe, Marjorie Nakibuule, Marvin Martin Ssejoba, David Oyamo, Rose Mulwana, Josephine Nabulime, Febronius Babirye, Abdusalaamu Kizito, Herve Lekuya, Akello Suzan Adakun, Robert Lukande, Andrew Kyazze, Irene Andia Biraro, Stephen Cose

If we are to break new grounds in TB research, we need to have a complete understanding of what is occurring at the site of infection in humans. Postmortem studies give us an opportunity to compare TB-involved and -uninvolved tissues, in both disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00822a9b7dcd171e865e56ccc2c19ba0
https://doi.org/10.1101/2023.03.14.532701

Treatment outcomes of drug resistant tuberculosis patients with multiple poor prognostic indicators in Uganda: A countrywide 5-year retrospective study

Autor: Bridget Nakazibwe, Sarah Mwanja, Carol Namugenyi, Febronius Babirye, Joshua Naloka, William Worodria, Mike Sempiira, Joseph Baruch Baluku, Rose Mulwana, Samuel Ntambi, Sylvia Nassozi, Sharon Namiiro, Richard Katuramu, Felix Bongomin, Irene Andia-Biraro, Martin Nabwana

Publikováno v: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 23, Iss, Pp 100221-(2021)

Background: Comorbid conditions and adverse drug events are associated with poor treatment outcomes among patients with drug resistant tuberculosis (DR – TB). This study aimed at determining the treatment outcomes of DR – TB patients with poor pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92284108f787432b236c5f489cc94904
http://europepmc.org/articles/PMC7856462

Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda

Autor: Irene Andia-Biraro, William Worodria, Robert Buyungo, Joseph Baruch Baluku, Amir Wasswa, Godwin Anguzu, Samuel Ntambi, Sylvia Nassozi, Rose Mulwana, Sharon Namiiro, Febronius Babirye, Mike Sempiira

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports

Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfdd4790d773f9813605c111d38cfe5
https://doi.org/10.1038/s41598-020-70472-6