Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rose Al Abosy"'
Autor:
Yashaswi Shrestha, Michael Quigley, Travis Hughes, Robert T Manguso, Natalie B Collins, Rose Al Abosy, Brian C Miller, Kevin Bi, Qihong Zhao, Jeffrey J Ishizuka, Kathleen B Yates, Hans W Pope, Marc Wadsworth, Alex K Shalek, Jesse S Boehm, William C Hahn, John G Doench, W Nicholas Haining
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Oncogenes act in a cell-intrinsic way to promote tumorigenesis. Whether oncogenes also have a cell-extrinsic effect on suppressing the immune response to cancer is less well understood.Methods We use an in vivo expression screen of known c
Externí odkaz:
https://doaj.org/article/2f18639e65804873a00ab93aef07c6bc
Autor:
Rose Al Abosy
This chapter focuses on the power of defiance in the workplace. It notes the power of anger and sadness in the process of defiance against oppression. Emotions could be used to resolve conflict such as focusing on the hurt in order to avoid discussio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f667e29584ced1d372933d43623f7729
https://doi.org/10.7591/cornell/9781501760273.003.0012
https://doi.org/10.7591/cornell/9781501760273.003.0012
Autor:
Kathleen B. Yates, W. Nicholas Haining, Thao H. Nguyen, Rose Al Abosy, Debattama R. Sen, Arlene H. Sharpe, Gordon J. Freeman, Matthew A. Coxe, Jacob E. Gillis, Emily F. Gaudiano, Brian C. Miller, Martin W. LaFleur
Publikováno v:
Nature Immunology. 20:1335-1347
CD8+ T cell exhaustion is a state of dysfunction acquired in chronic viral infection and cancer, characterized by the formation of Slamf6+ progenitor exhausted and Tim-3+ terminally exhausted subpopulations through unknown mechanisms. Here we establi
Autor:
Scott J. Rodig, Girish S. Naik, Evisa Gjini, Arpit Panda, Kevin Bi, Seth Maleri, Gabriel K. Griffin, W. Nicholas Haining, Martin W. LaFleur, Sarah A. Weiss, Margaret D. Zimmer, Kristen Felt, Robert T. Manguso, Arlene H. Sharpe, F. Stephen Hodi, Yamini V. Virkud, Jeffrey J. Ishizuka, Jenna L. Collier, Ana Lako, Debattama R. Sen, Juhi R. Kuchroo, Michael Manos, Rose Al Abosy, Brian C. Miller, Kathleen B. Yates, Flavian D. Brown, Dawn E. Comstock
Publikováno v:
Nat Immunol
T cell dysfunction is a hallmark of many cancers, but the basis for T cell dysfunction and the mechanisms by which antibody blockade of the inhibitory receptor PD-1 (anti-PD-1) reinvigorates T cells are not fully understood. Here we show that such th
Autor:
Martin W, LaFleur, Thao H, Nguyen, Matthew A, Coxe, Brian C, Miller, Kathleen B, Yates, Jacob E, Gillis, Debattama R, Sen, Emily F, Gaudiano, Rose, Al Abosy, Gordon J, Freeman, W Nicholas, Haining, Arlene H, Sharpe
Publikováno v:
Nature immunology
CD8+ T cell exhaustion is a state of dysfunction acquired in chronic viral infection and cancer, characterized by the formation of Slamf6+ progenitor exhausted and Tim-3+ terminally exhausted subpopulations through unknown mechanisms. Here we establi
Autor:
Lauer Georg, David Wolski, Sarah A. Weiss, Pierre Tonnerre, W. Nicholas Haining, Kathleen B. Yates, Kevin Bi, Martin W. LaFleur, Debattama R. Sen, Arlene H. Sharpe, Rose Al Abosy, Brian C. Miller
Publikováno v:
Cancer Immunology Research. 8:PR6-PR6
T-cell exhaustion describes an acquired dysfunction common in settings of cancer and chronic viral infection. Despite clinical efforts to rescue exhaustion, the fundamental mechanisms specifying this state, and the potential for reprogramming exhaust
Autor:
Arlene H. Sharpe, Jeffrey J. Ishizuka, Kathleen B. Yates, Michael Manos, Girish S. Naik, W. Nicholas Haining, Martin W. LaFleur, F. Stephen Hodi, Ana Lako, Yamini V. Virkud, Debattama R. Sen, Scott J. Rodig, Rose Al Abosy, Brian C. Miller, Evisa Gjini, Kristen Felt, Kevin Bi
Publikováno v:
Cancer Immunology Research. 8:A83-A83
T-cell dysfunction in the tumor microenvironment (TME) is a hallmark of many cancers. Reinvigoration of T-cell function by PD-1 checkpoint blockade can result in striking clinical responses, but is only effective in a minority of patients. The mechan
Autor:
Gabriel K. Griffin, Kathleen B. Yates, F. Stephen Hodi, Kevin Bi, Sarah A. Weiss, Seth Maleri, Robert T. Manguso, Arlene H. Sharpe, Yamini V. Virkud, Evisa Gjini, Kristen Felt, Scott J. Rodig, Debattama R. Sen, Flavian D. Brown, Dawn E. Comstock, Martin W. LaFleur, Brian C. Miller, Rose Al Abosy, Jeffrey J. Ishizuka, W. Nicholas Haining, Jenna L. Collier, Margaret D. Zimmer, Ana Lako, Arpit Panda, Girish S. Naik, Juhi R. Kuchroo, Michael Manos
Publikováno v:
Nature Immunology. 20:1556-1556
Autor:
Scott J. Rodig, Kathleen B. Yates, Arlene H. Sharpe, Debattama R. Sen, Kristen Felt, Martin W. LaFleur, Ana Lako, Girish S. Naik, Evisa Gjini, Kevin Bi, Brian C. Miller, Rose Al Abosy, W. Nicholas Haining, Yamini V. Virkud, F. Stephen Hodi, Michael Manos
Publikováno v:
Cancer Research. 79:2701-2701
T cell dysfunction in the tumor microenvironment (TME) is a hallmark of many cancers. Reinvigoration of T cell function by PD-1 checkpoint blockade can result in striking clinical responses, but is only effective in a minority of patients. The basis
Autor:
Natalie B Collins, Rose Al Abosy, Brian Miller, Kevin Bi, Robert Manguso, Kathleen Yates, W. Nicholas Haining
Publikováno v:
The Journal of Immunology. 202:58.17-58.17
Oncogenes act in a cell-intrinsic way to promote tumorigenesis. Whether oncogenes also have a cell-extrinsic effect on suppressing the immune response to cancer is less well understood. Here we use an in vivo screen of known cancer-associated somatic