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Metabotropic Glutamate Receptors as Drug Targets

Autor: Ahmad Abdulkarim, Rose Aimar, Gérard Barbanel, Janique Guiramand, Max Récasens

Publikováno v: Current Drug Targets
Current Drug Targets, Bentham Science Publishers, 2007, 8 (5), pp.651-81. ⟨10.2174/138945007780618544⟩

International audience; L-glutamate (Glu), the main excitatory amino acid neurotransmitter in the mammalian central nervous system, is involved in many physiological functions, including learning and memory, but also in toxic phenomena occurring in n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b9e86acb3e94ca33e5ff9229c2096f
https://doi.org/10.2174/138945007780618544

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Late N-acetylcysteine treatment prevents the deficits induced in the offspring of dams exposed to an immune stress during gestation

Autor: Rose Aimar, Tangui Maurice, Michel Vignes, Gilles Cambonie, Janique Guiramand, Fabien Lanté, Johann Meunier, Gérard Barbanel, Marie-Céleste de Jesus Ferreira, Catherine Cohen-Solal

Publikováno v: Hippocampus
Hippocampus, Wiley, 2008, 18 (6), pp.602-9. ⟨10.1002/hipo.20421⟩

International audience; Prenatal infection is a major stressful experience leading to enhanced susceptibility for mental illnesses in humans. We recently reported in rats, that oxidative stress and glutathione (GSH) shortage occurred in fetal male br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5fe69ae074559891ac3283fc42c1c56
https://hal.archives-ouvertes.fr/hal-00397553

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Neurodevelopmental damage after prenatal infection: role of oxidative stress in the fetal brain

Autor: Fabien Lanté, Mélanie Cavalier, Marie-Céleste de Jesus Ferreira, Janique Guiramand, Gérard Barbanel, Michel Vignes, Johann Meunier, Catherine Cohen-Solal, Tangui Maurice, Rose Aimar

Publikováno v: Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2007, 42 (8), pp.1231-45. ⟨10.1016/j.freeradbiomed.2007.01.027⟩

International audience; Prenatal infection is a major risk responsible for the occurrence of psychiatric conditions in infants. Mimicking maternal infection by exposing pregnant rodents to bacterial endotoxin lipopolysaccharide (LPS) also leads to ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1a57a0cc3104b3b4a3aa95ef55cfc8
https://hal.archives-ouvertes.fr/hal-00397595

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