Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Rose A. Maciewicz"'
Autor:
Yun Deng, Thomas A Perry, Philippa Hulley, Rose A Maciewicz, Joanna Mitchelmore, Darryl Perry, Staffan Larsson, Sophie Brachat, André Struglics, C Thomas Appleton, Stefan Kluzek, Nigel K Arden, David Felson, Brian Marsden, Brian D M Tom, Laura Bondi, Mohit Kapoor, Vicky Batchelor, Jennifer Mackay-Alderson, Vinod Kumar, L Stefan Lohmander, Tim J Welting, David A Walsh, Ana M Valdes, STEpUP OA Consortium, Tonia L Vincent, Fiona E Watt, Luke Jostins-Dean
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0309677 (2024)
ObjectivesTo develop a protocol for largescale analysis of synovial fluid proteins, for the identification of biological networks associated with subtypes of osteoarthritis.MethodsSynovial Fluid To detect molecular Endotypes by Unbiased Proteomics in
Externí odkaz:
https://doaj.org/article/1a7b992e033f487392bdc5e67be7b7f1
Autor:
John J. Cole, Bekir A. Faydaci, David McGuinness, Robin Shaw, Rose A. Maciewicz, Neil A. Robertson, Carl S. Goodyear
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Background Once bulk RNA-seq data has been processed, i.e. aligned and then expression and differential tables generated, there remains the essential process where the biology is explored, visualized and interpreted. Without the use of a vis
Externí odkaz:
https://doaj.org/article/9bca106272ef4240bc9afd063a856c67
Autor:
Masaru Suzuki, John J. Cole, Satoshi Konno, Hironi Makita, Hiroki Kimura, Masaharu Nishimura, Rose A. Maciewicz
Publikováno v:
Clinical and Translational Allergy, Vol 11, Iss 10, Pp n/a-n/a (2021)
Abstract Background Chronic airway diseases including chronic obstructive pulmonary disease (COPD) and asthma are heterogenous in nature and endotypes within are underpinned by complex biology. This study aimed to investigate the utility of proteomic
Externí odkaz:
https://doaj.org/article/350d910b3ad24cb48ea7afa0a21f259d
Autor:
Engin Baturcam, Stefan Vollmer, Holger Schlüter, Rose A. Maciewicz, Nisha Kurian, Outi Vaarala, Stephan Ludwig, Danen Mootoosamy Cunoosamy
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background The airway epithelium is a major target tissue in respiratory infections, and its antiviral response is mainly orchestrated by the interferon regulatory factor-3 (IRF3), which subsequently induces type I (β) and III (λ) interfer
Externí odkaz:
https://doaj.org/article/37834a1f40794b25b512aab2c43f11ac
Autor:
Chia-Hao Lin, Cheng-Jang Wu, Sunglim Cho, Rasika Patkar, Ling-Li Lin, Mei-Chi Chen, Elisabeth Israelsson, Joanne Betts, Magdalena Niedzielska, Shefali A. Patel, Han G. Duong, Romana R. Gerner, Chia-Yun Hsu, Matthew Catley, Rose A. Maciewicz, Hiutung Chu, Manuela Raffatellu, John T. Chang, Li-Fan Lu
Publikováno v:
bioRxiv
Regulatory T (Treg) cells are instrumental in establishing immunological tolerance. However, the precise effector mechanisms by which Treg cells control a specific type of immune response in a given tissue remains unresolved. By simultaneously studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191745d22cd68b14fbab9a868827295a
https://doi.org/10.1101/2023.02.20.529261
https://doi.org/10.1101/2023.02.20.529261
Autor:
Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006260 (2016)
Osteoarthritis is one of the most frequent and disabling diseases of the elderly. Only few genetic variants have been identified for osteoarthritis, which is partly due to large phenotype heterogeneity. To reduce heterogeneity, we here examined carti
Externí odkaz:
https://doaj.org/article/346cded1a0c64f81b7b42090748bb1f4
Autor:
Ingrid A. Laing, Siew-Kim Khoo, Stephen Oo, Franciska Prastanti, Peter N. Le Souëf, Laura Coleman, Niamh M. Troy, Janet Everard, Kimberley Franks, Lisa Öberg, Meredith L Borland, Anthony Bosco, James F. Read, Christopher McCrae, Joelene Bizzintino, Guicheng Zhang, Rose A. Maciewicz
Publikováno v:
The Journal of Immunology. 202:1845-1858
Asthma exacerbations are triggered by rhinovirus infections. We employed a systems biology approach to delineate upper-airway gene network patterns underlying asthma exacerbation phenotypes in children. Cluster analysis unveiled distinct IRF7hi versu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406c8dcaaa60504c5a6debc2d65cb0f7
https://doi.org/10.4049/jimmunol.1800178
https://doi.org/10.4049/jimmunol.1800178
Autor:
Daniel M. Wall, Gabrielle T Belz, John J. Cole, Vuk Cerovic, Edward S Lee, Gérard Eberl, Natalie Papazian, Michio Tomura, Verena Kästele, David R. Withers, Carl S. Goodyear, Tom Cupedo, Simon Milling, Rose A. Maciewicz, Johannes U Mayer
Publikováno v:
Mucosal Immunology, 14(3), 717-727. Nature Publishing Group
Mucosal immunology 14(3), 717-727 (2021). doi:10.1038/s41385-020-00366-3
Mucosal Immunology
Mucosal Immunology, 2021, 14 (3), pp.717-727. ⟨10.1038/s41385-020-00366-3⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (3), pp.717-727. ⟨10.1038/s41385-020-00366-3⟩
Mucosal immunology 14(3), 717-727 (2021). doi:10.1038/s41385-020-00366-3
Mucosal Immunology
Mucosal Immunology, 2021, 14 (3), pp.717-727. ⟨10.1038/s41385-020-00366-3⟩
Mucosal Immunology, Nature Pub. Group, 2021, 14 (3), pp.717-727. ⟨10.1038/s41385-020-00366-3⟩
Mucosal immunology 14(3), 717-727 (2021). doi:10.1038/s41385-020-00366-3
Published by Nature Publishing Group, New York, NY
Published by Nature Publishing Group, New York, NY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb1b01bbcd7ac1d48e655fad2240942
Autor:
John J. Cole, Neil Robertson, Carl S. Goodyear, David McGuinness, Rose A. Maciewicz, Robin Shaw, Bekir A. Faydaci
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-21 (2021)
Background Once bulk RNA-seq data has been processed, i.e. aligned and then expression and differential tables generated, there remains the essential process where the biology is explored, visualized and interpreted. Without the use of a visualisatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b70303c11a6fd6417bfea551be5208
https://pubmed.ncbi.nlm.nih.gov/34412594
https://pubmed.ncbi.nlm.nih.gov/34412594
Autor:
Verena, Kästele, Johannes, Mayer, Edward S, Lee, Natalie, Papazian, John J, Cole, Vuk, Cerovic, Gabrielle, Belz, Michio, Tomura, Gerard, Eberl, Carl, Goodyear, Rose A, Maciewicz, Daniel, Wall, Tom, Cupedo, David R, Withers, Simon, Milling
Publikováno v:
Mucosal immunology. 14(3)
Innate lymphoid cells (ILCs) are enriched in mucosae and have been described as tissue-resident. Interestingly, ILCs are also present within lymph nodes (LNs), in the interfollicular regions, the destination for lymph-migratory cells. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff6dc88c8edbe0492772c4ea77e9de14
https://pubmed.ncbi.nlm.nih.gov/33960510
https://pubmed.ncbi.nlm.nih.gov/33960510