Zobrazeno 1 - 10
of 2 246
pro vyhledávání: '"Rose, John P"'
Autor:
Kristin Hösel, Büsra Chasan, Jan Tode, Stefan Rose-John, Johann Baptist Roider, Christoph Ehlken
Publikováno v:
Journal of Ophthalmic Inflammation and Infection, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Purpose The aim of this study was to assess the functional and clinical impact of intravitreal administration of a neutralizing anti-IL-6 antibody in the treatment of experimental autoimmune uveitis (EAU) in mice. Methods EAU was induced in
Externí odkaz:
https://doaj.org/article/ab15c184b47b45a2943cd1cf13fb8556
Autor:
Christina Sternberg, Martin Raigel, Tanja Limberger, Karolína Trachtová, Michaela Schlederer, Desiree Lindner, Petra Kodajova, Jiaye Yang, Roman Ziegler, Jessica Kalla, Stefan Stoiber, Saptaswa Dey, Daniela Zwolanek, Heidi A. Neubauer, Monika Oberhuber, Torben Redmer, Václav Hejret, Boris Tichy, Martina Tomberger, Nora S. Harbusch, Jan Pencik, Simone Tangermann, Vojtech Bystry, Jenny L. Persson, Gerda Egger, Sarka Pospisilova, Robert Eferl, Peter Wolf, Felix Sternberg, Sandra Högler, Sabine Lagger, Stefan Rose-John, Lukas Kenner
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Background Prostate cancer ranks as the second most frequently diagnosed cancer in men worldwide. Recent research highlights the crucial roles IL6ST-mediated signaling pathways play in the development and progression of various cancers, part
Externí odkaz:
https://doaj.org/article/b138c0eace4d4d388c5bcd9f679c1598
Autor:
Bodie Curren, Tufael Ahmed, Ridwan B. Rashid, Ismail Sebina, Md. Al Amin Sikder, Daniel R. Howard, Mariah Alorro, Md. Ashik Ullah, Alec Bissell, Muhammed Mahfuzur Rahman, Michael A. Pearen, Grant A. Ramm, Antiopi Varelias, Stefan Rose-John, Kelli P.A. MacDonald, Robert Hoelzle, Páraic Ó Cuív, Kirsten M. Spann, Paul G. Dennis, Simon Phipps
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114974- (2024)
Summary: A poor maternal diet during pregnancy predisposes the infant to severe lower respiratory tract infections (sLRIs), which, in turn, increases childhood asthma risk; however, the underlying mechanisms remain poorly understood. Here, we show th
Externí odkaz:
https://doaj.org/article/35ed73a82c044bd8a5ad26ee440d31fb
Autor:
María Ángeles Rodríguez-Hernández, Mercedes Baena-Bustos, David Carneros, Carola Zurita-Palomo, Pablo Muñoz-Pinillos, Jaime Millán, Francisco Javier Padillo, Cristian Smerdou, Cayetano von Kobbe, Stefan Rose-John, Matilde Bustos
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105132- (2024)
Summary: Background: SARS-CoV-2 infection is considered as a relapsing inflammatory process with a dysregulation of IL-6 signalling. Classic IL-6 signalling is thought to represent a defence mechanism against pathogens. In contrast, IL-6 trans-signal
Externí odkaz:
https://doaj.org/article/cb1a454d27374e47aa940a4799b66b43
Autor:
Zaid W. El-Husseini, Dmitry Khalenkow, Andy Lan, Thys van der Molen, Chris Brightling, Alberto Papi, Klaus F. Rabe, Salman Siddiqui, Dave Singh, Monica Kraft, Bianca Beghe, Maarten van den Berge, Djoke van Gosliga, Martijn C. Nawijn, Stefan Rose-John, Gerard H. Koppelman, Reinoud Gosens
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Asthma is stratified into type 2-high and type 2-low inflammatory phenotypes. Limited success has been achieved in developing drugs that target type 2-low inflammation. Previous studies have linked IL-6 signaling to severe asthma.
Externí odkaz:
https://doaj.org/article/e4d93162eadc447d86daca4b0d26e0df
The notion of hypothetical bias (HB) constitutes, arguably, the most fundamental issue in relation to the use of hypothetical survey methods. Whether or to what extent choices of survey participants and subsequent inferred estimates translate to real
Externí odkaz:
http://arxiv.org/abs/2102.02940
This paper reviews methods of hypothetical bias (HB) mitigation in choice experiments (CEs). It presents a bibliometric analysis and summary of empirical evidence of their effectiveness. The paper follows the review of empirical evidence on the exist
Externí odkaz:
http://arxiv.org/abs/2102.02945
Autor:
Jan Pencik, Cecile Philippe, Michaela Schlederer, Emine Atas, Matteo Pecoraro, Sandra Grund-Gröschke, Wen (Jess) Li, Amanda Tracz, Isabel Heidegger, Sabine Lagger, Karolína Trachtová, Monika Oberhuber, Ellen Heitzer, Osman Aksoy, Heidi A. Neubauer, Bettina Wingelhofer, Anna Orlova, Nadine Witzeneder, Thomas Dillinger, Elisa Redl, Georg Greiner, David D’Andrea, Johnny R. Östman, Simone Tangermann, Ivana Hermanova, Georg Schäfer, Felix Sternberg, Elena E. Pohl, Christina Sternberg, Adam Varady, Jaqueline Horvath, Dagmar Stoiber, Tim I. Malcolm, Suzanne D. Turner, Eileen E. Parkes, Brigitte Hantusch, Gerda Egger, Stefan Rose-John, Valeria Poli, Suneil Jain, Chris W. D. Armstrong, Gregor Hoermann, Vincent Goffin, Fritz Aberger, Richard Moriggl, Arkaitz Carracedo, Cathal McKinney, Richard D. Kennedy, Helmut Klocker, Michael R. Speicher, Dean G. Tang, Ali A. Moazzami, David M. Heery, Marcus Hacker, Lukas Kenner
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-25 (2023)
Abstract Prostate cancer (PCa) is a common and fatal type of cancer in men. Metastatic PCa (mPCa) is a major factor contributing to its lethality, although the mechanisms remain poorly understood. PTEN is one of the most frequently deleted genes in m
Externí odkaz:
https://doaj.org/article/55713eefba5d493d89c7d396451b3eb7
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