Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Roscoe Atkinson"'
Autor:
Roscoe Atkinson, Timothy W. Phares, David R. Hinton, Cornelia C. Bergmann, Stephen A. Stohlman
Publikováno v:
The Journal of Immunology
The T cell inhibitory ligand B7-H1 hinders T cell-mediated virus control, but also ameliorates clinical disease during autoimmune and virus-induced CNS disease. In mice infected with gliatropic demyelinating coronavirus, B7-H1 expression on oligodend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ec5ea251846959caa85d4a2baab2b8
https://doi.org/10.4049/jimmunol.1001984
https://doi.org/10.4049/jimmunol.1001984
Autor:
Stephen A. Stohlman, Chandran Ramakrishna, Timothy W. Phares, Gabriel I. Parra, Cornelia C. Bergmann, Roscoe Atkinson, Lieping Chen, Alan L. Epstein
Publikováno v:
The Journal of Immunology
The neurotropic coronavirus JHM strain of mouse hepatitis virus persists in oligodendroglia despite the presence of virus-specific CD8 T cells. Expression of programmed death 1 (PD-1) and B7-H1 were studied during acute and persistent infection to ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8038ef0af2e58def07ccea256da5c3
https://doi.org/10.4049/jimmunol.0803557
https://doi.org/10.4049/jimmunol.0803557
Autor:
Stephen A. Stohlman, Roscoe Atkinson, Cornelia C. Bergmann, David R. Hinton, Derek D. C. Ireland
Publikováno v:
Journal of Virology
Neurotropic coronavirus infection induces expression of both beta interferon (IFN-β) RNA and protein in the infected rodent central nervous system (CNS). However, the relative contributions of type I IFN (IFN-I) to direct, cell-type-specific virus c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1174e8b5e822fe5cd2129d3dd1697b2f
Autor:
John Mario González, Jason B. Hoskin, Cornelia C. Bergmann, Roscoe Atkinson, Stephen A. Stohlman, David R. Hinton, Chandran Ramakrishna, Wendy B. Macklin
Publikováno v:
The American Journal of Pathology
Infection of the central nervous system (CNS) by the neurotropic JHM strain of mouse hepatitis virus (JHMV) induces an acute encephalomyelitis associated with demyelination. To examine the anti-viral and/or regulatory role of interferon-gamma (IFN-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769c1501d5c20ff252647790ffea6986
https://doi.org/10.2353/ajpath.2006.050496
https://doi.org/10.2353/ajpath.2006.050496
Autor:
John Mario González, David R. Hinton, Cornelia C. Bergmann, Wendy B. Macklin, Stephen A. Stohlman, Roscoe Atkinson, Claudia Hindinger, Babette Fuss
Publikováno v:
Journal of Neuroscience Research
Interferon-gamma (IFN-gamma) is a major proinflammatory cytokine, and binding to its nearly ubiquitous receptor induces a wide variety of biological functions. To explore the role(s) of IFN-gamma signaling in astrocytes, transgenic mice (GFAP/IFN-gam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed247ac622b5a81ec35fb6a128b14e90
http://europepmc.org/articles/PMC7167034
http://europepmc.org/articles/PMC7167034
Autor:
Z. Zhu, Joel E. Schechter, Thomas Ritter, Douglas Stevenson, Robert W. Crow, Austin K. Mircheff, Roscoe Atkinson, Melvin D. Trousdale, Swaraj Bose
Publikováno v:
Cornea. 22:343-351
Purpose. To evaluate the effect of tumor necrosis factor (TNF) inhibitor protein on lacrimal gland immunopathology and ocular surface disease resulting from induced dacryoadenitis. Methods. Autoimmune dacryoadenitis was induced in rabbits by injectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6327e19df366317d442e1d8300d4cf
https://doi.org/10.1097/00003226-200305000-00012
https://doi.org/10.1097/00003226-200305000-00012
Matrix Metalloproteinases in the Neocortex and Spinal Cord of Amyotrophic Lateral Sclerosis Patients
Autor:
Carol A. Miller, Giselle P. Lim, Jon R. Backstrom, Roscoe Atkinson, Zoltán A. Tökés, Michael Cullen
Publikováno v:
Journal of Neurochemistry. 67:251-259
Matrix metalloproteinases (MMPs) were analyzed by immunohistochemistry and zymography in amyotrophic lateral sclerosis (ALS) and control brain and spinal cord specimens. Three major bands of enzyme activity (70, 100, and 130 kDa) were consistently ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d6d8fbca15ae98b1b0225a7c0239d6
https://doi.org/10.1046/j.1471-4159.1996.67010251.x
https://doi.org/10.1046/j.1471-4159.1996.67010251.x
Autor:
Stephen J. Forman, Harry Openshaw, Roscoe Atkinson, Ashwin Kashyap, Brett T. Lund, Irena Sniecinski, Leslie P. Weiner
Publikováno v:
Biology of Blood and Marrow Transplantation. 6:563-575
Multiple sclerosis (MS) is an immune-mediated disease that may be amenable to high-dose immunosuppression with peripheral blood stem cell transplantation (SCT) in selected patients. Five MS patients (all women, ages 39-47 years) received granulocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be0153e54ca0bbe3c093fbba3e8d187
https://doi.org/10.1016/s1083-8791(00)70066-8
https://doi.org/10.1016/s1083-8791(00)70066-8
Autor:
David R. Hinton, Cornelia C. Bergmann, Stephen A. Stohlman, Roscoe Atkinson, John O. Fleming, Norman W. Marten
Publikováno v:
The Journal of Immunology. 164:4080-4088
Acute and chronic demyelination are hallmarks of CNS infection by the neurotropic JHM strain of mouse hepatitis virus. Although infectious virus is cleared by CD8+ T cells, both viral RNA and activated CD8+ T cells remain in the CNS during persistenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d271b808c4a163b936318f5c91c42d91
https://doi.org/10.4049/jimmunol.164.8.4080
https://doi.org/10.4049/jimmunol.164.8.4080
Autor:
Cornelia C. Bergmann, David R. Hinton, Roscoe Atkinson, Beatriz Parra, Stephen A. Stohlman, Mark T. Lin
Publikováno v:
Journal of Virology. 74:2447-2450
The pathogenesis of the neurotropic strain of mouse hepatitis virus in Fas-deficient mice suggested that Fas-mediated cytotoxicity may be required during viral clearance after the loss of perforin-mediated cytotoxicity. The absence of both Fas- and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aec494ed4ad46f57e652986e13092ec
https://doi.org/10.1128/jvi.74.5.2447-2450.2000
https://doi.org/10.1128/jvi.74.5.2447-2450.2000