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Seralutinib in adults with pulmonary arterial hypertension (TORREY): a randomised, double-blind, placebo-controlled phase 2 trial.

Autor: Frantz RP; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: frantz.robert@mayo.edu., McLaughlin VV; Department of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA; Frankel Cardiovascular Center, Ann Arbor, MI, USA., Sahay S; Division of Pulmonary, Critical Care & Sleep Medicine, Houston Methodist Hospital, Houston, TX, USA., Escribano Subías P; Department of Cardiology, CIBERCV, Complutense University, Madrid, Spain; University Hospital 12 de Octubre, Madrid, Spain., Zolty RL; Department of Cardiovascular Medicine, University of Nebraska College of Medicine, Omaha, NE, USA; University of Nebraska Medical Center, Omaha, NE, USA., Benza RL; Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Mount Sinai Hospital, New York, NY, USA., Channick RN; Department of Clinical Medicine, University of California Los Angeles, Los Angeles, CA, USA; UCLA Medical Center, Los Angeles, CA, USA., Chin KM; Division of Pulmonary and Critical Care Medicine, UT Southwestern Medical Center, Dallas, TX, USA; UT Southwestern Medical Center, Dallas, TX, USA., Hemnes AR; Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, TN, USA; Vanderbilt University Medical Center, Nashville, TN, USA., Howard LS; National Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, London, UK; Hammersmith Hospital, London, UK., Sitbon O; Department of Respiratory Medicine, Hôpital Bicêtre (AP-HP), Le Kremlin-Bicêtre, France; Université Paris-Saclay, Le Kremlin-Bicêtre, France., Vachiéry JL; Department of Cardiology, Université Libre de Bruxelles, Brussels, Belgium; HUB-Hôpital Erasme, Brussels, Belgium., Zamanian RT; Department of Medicine-Pulmonary, Allergy & Critical Care Medicine, Stanford University School of Medicine, Stanford, CA, USA; Stanford Medicine, Stanford, CA, USA., Cravets M; Gossamer Bio, San Diego, CA, USA., Roscigno RF; Gossamer Bio, San Diego, CA, USA., Mottola D; Gossamer Bio, San Diego, CA, USA., Osterhout R; Gossamer Bio, San Diego, CA, USA., Bruey JM; Gossamer Bio, San Diego, CA, USA., Elman E; Gossamer Bio, San Diego, CA, USA., Tompkins CA; Gossamer Bio, San Diego, CA, USA., Parsley E; Gossamer Bio, San Diego, CA, USA., Aranda R; Gossamer Bio, San Diego, CA, USA., Zisman LS; Gossamer Bio, San Diego, CA, USA., Ghofrani HA; Department of Internal Medicine, Justus-Liebig-University Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Institute for Lung Health, Cardio-Pulmonary Institute, Giessen, Germany; German Center for Lung Research (DZL), Giessen, Germany; Department of Medicine, Imperial College, London, UK.

Publikováno v: The Lancet. Respiratory medicine [Lancet Respir Med] 2024 Jul; Vol. 12 (7), pp. 523-534. Date of Electronic Publication: 2024 May 02.

Nitrogen dioxide reducing ascorbic acid technologies in the ventilator circuit leads to uniform NO concentration during inspiration.

Autor: Pezone MJ; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, 736 Cambridge Street CMP-2, Boston, MA 02134, USA., Wakim MG; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, 736 Cambridge Street CMP-2, Boston, MA 02134, USA., Denton RJ; GeNO LLC, 2941 Oxbow Circle, Cocoa, FL 32926, USA., Gamero LG; GeNO LLC, 2941 Oxbow Circle, Cocoa, FL 32926, USA., Roscigno RF; GeNO LLC, 2941 Oxbow Circle, Cocoa, FL 32926, USA., Gilbert RJ; Department of Chemistry and Chemical Biology, Northeastern University, 334 Huntington Ave., Boston, MA 02115, USA., Lovich MA; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, 736 Cambridge Street CMP-2, Boston, MA 02134, USA. Electronic address: Mark.Lovich@steward.org.

Publikováno v: Nitric oxide : biology and chemistry [Nitric Oxide] 2016 Aug 31; Vol. 58, pp. 42-50. Date of Electronic Publication: 2016 Jun 02.

Generation of purified nitric oxide from liquid N2O4 for the treatment of pulmonary hypertension in hypoxemic swine.

Autor: Lovich MA; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, Boston, MA, United States. Electronic address: Mark.Lovich@steward.org., Fine DH; GeNO LLC, Cocoa, FL, United States., Denton RJ; GeNO LLC, Cocoa, FL, United States., Wakim MG; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, Boston, MA, United States., Wei AE; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, Boston, MA, United States., Maslov MY; Department of Anesthesiology, Pain Medicine, and Critical Care, Steward St. Elizabeth's Medical Center, Boston, MA, United States., Gamero LG; GeNO LLC, Cocoa, FL, United States., Vasquez GB; GeNO LLC, Cocoa, FL, United States., Johnson BJ; GeNO LLC, Cocoa, FL, United States., Roscigno RF; GeNO LLC, Cocoa, FL, United States., Gilbert RJ; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.

Publikováno v: Nitric oxide : biology and chemistry [Nitric Oxide] 2014 Feb 15; Vol. 37, pp. 66-72. Date of Electronic Publication: 2014 Feb 07.