Metal-Free Aminophosphonation: Eco-Friendly Synthesis and Photophysical Properties of Fluorescent 3-(Aminoimidazo[1,2-a]Pyridin-2-yl)Phosphonates.

Autor: Roscales S; Instituto Pluridisciplinar, Universidad Complutense, Paseo de Juan XXIII, 1, 28040-, Madrid, Spain., Csáky AG; Instituto Pluridisciplinar, Universidad Complutense, Paseo de Juan XXIII, 1, 28040-, Madrid, Spain.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Dec 09; Vol. 63 (50), pp. e202412300. Date of Electronic Publication: 2024 Oct 24.

One-pot Cascade Synthesis of Pyrazole-based Isosteres of Valdecoxib by a [3+2] Cycloaddition/[1,5] Sigmatropic Rearrangement Sequence and Evaluation of their COX Inhibitory Activity

Autor: Roscales, S., Bechmann, N., Pietzsch, J., Kniess, T.

Publikováno v: Heterocycles 98(2019)3, 416-428

A series of 5-methyl-3,4-diaryl-substituted 1H-pyrazoles, N-isosteres of valdecoxib, was synthesized by a [3+2] cycloaddition/[1,5] sigmatropic rearrangement sequence starting from tosylhydrazine, aryl methyl ketones and terminal aryl alkynes bearing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::a983fa1dcbd917e0fa504d6190b69c27
https://www.hzdr.de/publications/Publ-27859-2

Novel Valdecoxib Derivates by Ruthenium-catalyzed 1,3-Dipolar Cycloaddition of Nitrile Oxides with Alkynes - Synthesis and COX-2 Inhibition Affinity

Autor: Roscales, S., Bechmann, N., Weiss, D. H., Köckerling, M., Pietzsch, J., Kniess, T.

Publikováno v: MedChemComm 9(2018), 534-544

Novel valdecoxib-based cyclooxygenase-2 inhibitors were synthesized in one step via 1,3-dipolar cycloaddition of nitrile oxides with a series of eleven, partly novel aryl alkynes. Application of Ru(II)-catalysis leads preferably to the formation of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::7d9b492030175f7f286ba4efdd0ad658
https://www.hzdr.de/publications/Publ-25228-1

Synthesis of Ketones by C-H Functionalization of Aldehydes with Boronic Acids under Transition-Metal-Free Conditions.

Autor: Roscales S; Instituto Pluridisciplinar, Universidad Complutense, Campus de Excelencia Internacional Moncloa, Paseo de Juan XXIII, 1, 28040, Madrid, Spain., Csáky AG; Instituto Pluridisciplinar, Universidad Complutense, Campus de Excelencia Internacional Moncloa, Paseo de Juan XXIII, 1, 28040, Madrid, Spain.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Apr 12; Vol. 60 (16), pp. 8728-8732. Date of Electronic Publication: 2021 Mar 05.

1,2-stereochemical induction in the PdII-catalyzed conjugate addition of boronic acids

Autor: Roscales, S., Sánchez, Francisco, Csákÿ, Aurelio G.

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Palladium(II) catalysis has been used in the substrate-controlled 1,2-chiral induction of the conjugate addition of boronic acids to enantiopure α,β-unsaturated ketones and esters without competition from the Mirozoki-Heck reaction. Bedford's palla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::93480ca6c0944f59c6d124efc7695596
http://hdl.handle.net/10261/117697