Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Rosaura, Casas"'
Autor:
Sara Puente-Marin, Fabrícia Dietrich, Peter Achenbach, Hugo Barcenilla, Johnny Ludvigsson, Rosaura Casas
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
GAD-alum given into lymph nodes to Type 1 diabetes (T1D) patients participating in a multicenter, randomized, placebo-controlled double-blind study seemed to have a positive effect for patients with DR3DQ2 haplotype, who showed better preservation of
Externí odkaz:
https://doaj.org/article/d963aa7ed1834bd6b443394cf237d62d
Autor:
Daniel Espes, Per-Ola Carlsson, José Caballero-Corbalan, Rosaura Casas, Louise Magnusson, Erik Schwarcz
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 10, Iss 6 (2022)
Introduction Pregnancy entails both pancreatic adaptations with increasing β-cell mass and immunological alterations in healthy women. In this study, we have examined the effects of pregnancy on β-cell function and immunological processes in long-s
Externí odkaz:
https://doaj.org/article/702939426c34474a8c7c80aadddeba32
Autor:
Marcus Lind, Johnny Ludvigsson, Christoph Nowak, Linnea Eriksson, Pedro F Teixeira, Martina Widman, Anton Lindqvist, Rosaura Casas, Ulf Hannelius
Publikováno v:
BMJ Open, Vol 12, Iss 10 (2022)
Introduction Type 1 diabetes (T1D) is an autoimmune disease leading to the destruction of the insulin-producing beta cells resulting in insulin deficiency and hyperglycaemic. Today, no approved therapy exists to halt this detrimental immunologic proc
Externí odkaz:
https://doaj.org/article/3fbbe4973702453597baa7c8264e56d9
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Antigen-specific immunotherapy is an appealing strategy to preserve beta-cell function in type 1 diabetes, although the approach has yet to meet its therapeutic endpoint. Direct administration of autoantigen into lymph nodes has emerged as an alterna
Externí odkaz:
https://doaj.org/article/99dd57ea8f8148d39f1b7fbb089923e5
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophil extracellular traps (NETs) and mitochondrial DNA (mtDNA) are inflammatory mediators involved in the development of type 1 diabetes (T1D). Pancreas-infiltrating neutrophils can release NETs, contributing to the inflammatory process. Levels
Externí odkaz:
https://doaj.org/article/3c460eb4fd264a5a948e12df099c32be
Autor:
Rosaura Casas, Fabrícia Dietrich, Hugo Barcenilla, Beatriz Tavira, Jeanette Wahlberg, Peter Achenbach, Johnny Ludvigsson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In spite of intensive treatment Type 1 diabetes leads to serious complications. Preservation of residual beta cell function makes the disease milder, facilitates treatment, prevents complications and increase survival. So far immune interventions hav
Externí odkaz:
https://doaj.org/article/133573f75f43498aa6060643480b1a31
Autor:
Johnny Ludvigsson, Indusmita Routray, Sriramulu Elluru, Per Leanderson, Helena E Larsson, Björn Rathsman, Ragnar Hanås, Annelie Carlsson, Torben Ek, Ulf Samuelsson, Torun Torbjörnsdotter, Jan Åman, Eva Örtqvist, Karun Badwal, Craig Beam, Rosaura Casas
Publikováno v:
Future Science OA, Vol 6, Iss 7 (2020)
Aim: Double-blind placebo-controlled intervention using glutamic acid decarboxylase (GAD)-alum, vitamin D and Ibuprofen in recent onset Type I diabetes (T1D). Methods: 64 patients (T1D since
Externí odkaz:
https://doaj.org/article/377a1c7fd105422e99f37abf119e20f1
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Despite that autoimmune diseases share similar immunogenetic mechanisms, studies comparing the protein composition in peripheral blood from patients with autoimmune endocrine diseases are limited. In this study, we applied proximity extension assay t
Externí odkaz:
https://doaj.org/article/8a7b62185f7b45b19f4e8def1d9bdb59
Autor:
Louise Magnusson, Hugo Barcenilla, Mikael Pihl, Sophie Bensing, Daniel Espes, Per-Ola Carlsson, Rosaura Casas
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Although there is evidence that autoimmune diseases share similar immunogenetic mechanisms, studies comparing peripheral CD45+ cells from patients with autoimmune endocrine diseases in parallel are limited. In this study, we applied high-dimensional
Externí odkaz:
https://doaj.org/article/c45f2259a94b4242be3a2f773ed8f5d2
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Type 1 diabetes (T1D) is characterized by autoimmune destruction of insulin producing β-cells. The time from onset of islet autoimmunity to manifest clinical disease can vary widely in length, and it is fairly uncharacterized both clinically and imm
Externí odkaz:
https://doaj.org/article/07bddbac4c2649419c22f871b91f21f9