IL12RB1 allele bias in human TH cells is regulated by functional SNPs in its 3′UTR

Autor: Rosas Mejia, Oscar, Claeys, Tiffany A., Williams, Amanda, Zafar, Ayesha, Robinson, Richard T.

Publikováno v: In Cytokine October 2022 158

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Evaluation of early innate and adaptive immune responses to the TB vaccine Mycobacterium bovis BCG and vaccine candidate BCGΔBCG1419c.

Autor: Gunasena, Manuja, Shukla, Rajni Kant, Yao, Naiquan, Rosas Mejia, Oscar, Powell, Michael D., Oestreich, Kenneth J., Aceves-Sánchez, Michel de Jesús, Flores-Valdez, Mario Alberto, Liyanage, Namal P. M., Robinson, Richard T.

Publikováno v: Scientific Reports; 7/20/2022, Vol. 12 Issue 1, p1-16, 16p

Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.

Autor: Eltobgy MM; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Neuroscience graduate program, The Ohio State University, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Zani A; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Kenney AD; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Estfanous S; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Faculty of Pharmacy, Helwan University, Cairo,11731 Egypt., Kim E; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210., Badr A; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Carafice C; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Daily K; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Whitham O; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Pietrzak M; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43210., Webb A; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43210., Kawahara J; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Eddy AC; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Denz P; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Lu M; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210., Kc M; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205., Peeples ME; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Center for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205., Li J; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210., Zhu J; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Pathology, The Ohio State University, Columbus, OH 43210., Que J; Division of Digestive and Liver Diseases and Center for Human Development, Department of Medicine, Columbia University, New York, NY 10027., Robinson R; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Rosas Mejia O; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Rayner RE; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210., Hall-Stoodley L; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Seveau S; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Gavrilin MA; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Zhang X; Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43210., Thomas J; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322., Kohlmeier JE; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322., Suthar MS; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322.; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322.; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322., Oltz E; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210., Tedeschi A; Department of Neuroscience, Chronic Brain Injury Discovery Theme, The Ohio State University, Columbus, OH 43210., Robledo-Avila FH; Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205., Partida-Sanchez S; Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205., Hemann EA; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Abdelrazik E; Center for Informatics Science, Nile University, Giza, 12525, Egypt., Forero A; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Nimjee SM; Department of Neurological Surgery, The Ohio State University, Columbus, OH 43210., Boyaka PN; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210., Cormet-Boyaka E; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210., Yount JS; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210., Amer AO; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Columbus, OH 43210.; Infectious Diseases Institute, The Ohio State University, Columbus, OH 43210.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 May 24; Vol. 119 (21), pp. e2202012119. Date of Electronic Publication: 2022 May 19.