Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Rosario Samanin"'
Publikováno v:
Annals of the New York Academy of Sciences. 499:156-166
Experiments using the binding of various ligands for monoamines to rat brain membranes and synaptosomal preparations for studying monoamine uptake and release have shown that d-fenfluramine is more potent than the l isomer in inhibiting 5-HT uptake,
Autor:
Rosario Samanin, Stefania Parini, Roberto W. Invernizzi, Giuseppina Sacchetti, Sabrina Acconcia
Publikováno v:
British Journal of Pharmacology. 139:1281-1288
Using in vivo intracerebral microdialysis in conscious, freely moving rats, we examined the effect of flibanserin, a potential antidepressant drug with high affinity for human 5-HT1A receptors and four–50-fold lower affinity for 5-HT2A and D4 recep
Publikováno v:
Journal of Neurochemistry. 63:195-200
Experiments were performed to confirm that noradrenergic terminals regulate extracellular concentrations of dopamine (DA) in the frontal cortex of rats. The effects of 20 mg/kg 1-[2-[bis(4-fluorphenyl)methoxy]-ethyl]-4-(3- phenylpropyl)piperazine (GB
Autor:
Marcus Rattray, Rosario Samanin, Marco Gobbi, Caterina Bendotti, Tiziana Mennini, S. Baldessari
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
After a single intraperitoneal injection of the irreversible tryptophan hydroxylase inhibitor p-chlorophenylalanine (PCPA; 300 mg/kg), there was a rapid down-regulation of serotonin (5-HT) transporter mRNA levels in cell bodies. This change was signi
Publikováno v:
Journal of Neurochemistry. 82:93-100
The present study investigated whether 5-HT(2C) receptors in the ventrotegmental area and prefrontal cortex regulate basal and stimulus-evoked dopamine release in the prefrontal cortex. Using the in vivo microdialysis technique in conscious rats, we
Publikováno v:
Psychopharmacology. 158:39-47
Objective: The present study investigated the effect of stimulating 5-HT1A receptors in the dorsal raphe on the impairment of spatial learning caused by intrahippocampal 7-chloro-kynurenic acid (7-Cl-Kyn) in naive rats and in rats familiar with the g
Autor:
Rosario Samanin, Roberto W. Invernizzi, Silvio Caccia, Stefania Parini, Claudia Fracasso, K Annoni, Giuseppina Sacchetti
Publikováno v:
British Journal of Pharmacology. 132:183-188
1. This study investigated the effect of acute (2 days) and chronic (14 days) treatment with a selective inhibitor of noradrenaline uptake, reboxetine (10 mg kg(-1) day(-1)) by osmotic pumps, on extracellular noradrenaline and the sensitivity of alph
Publikováno v:
British Journal of Pharmacology. 131:375-381
We studied the effects of low doses of 8-OH-DPAT, a 5-HT1A receptor agonist, on the impairment of spatial learning caused by scopolamine injected into the CA1 region of the dorsal hippocampus of rats performing a two-platform spatial discrimination t
Publikováno v:
Neuropharmacology. 39:1037-1043
8-OH-DPAT [8-hydroxy-2-(di-N-propylamino)tetralin], a 5-HT(1A) receptor agonist, and S 15535 (4-benzodioxan-5-yl)1-(indan-2-yl)piperazine, a partial agonist at 5-HT(1A) receptors, were administered into the dorsal raphe nucleus and dorsal hippocampus
Autor:
Rosario Samanin, Mirjana Carli
Publikováno v:
Psychopharmacology. 149:259-268
Rationale: Whilst several studies have investigated the role of serotonergic receptor subtypes in learning and memory, relatively few studies have examined their role in attentional processes. Objective: The present study investigated the role of pre