Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rosario Patiño-Molina"'
Autor:
Rosario González-Muñiz, Ivan Cubero-Lajo, Rosario Patiño-Molina, M. Jesús Pérez de Vega, M. Teresa García-López
Publikováno v:
Tetrahedron Letters. 48:3613-3616
Chiral 1,3,6-trisubstituted 2,4-dioxohexahydropyrimidines were easily synthesized by reaction of homoaspartic acid derivatives with isocyanates, followed by cyclization of the resulting urea, and alkylation at N1 position.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3eb8248b97cdb5f329f53e0bb321cb
https://doi.org/10.1016/j.tetlet.2007.03.066
https://doi.org/10.1016/j.tetlet.2007.03.066
Autor:
Joaquín Del Río, M. Teresa García-López, Rosario González-Muñiz, Edurne Cenarruzabeitia, Rosario Patiño-Molina
Publikováno v:
Synthesis. 2007:1047-1053
Unprecedented trisubstituted tetrahydropyrimidine-2,4-diones were easily synthesized in two steps involving Boc-amide protection and controlled ring opening, from perhydropyrazino[1,2- F]pyrimidine-3,6,8-triones. These bicyclic derivatives were prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a33847ab26cf9bb04872f7cb1b0fda46
https://doi.org/10.1055/s-2007-965962
https://doi.org/10.1055/s-2007-965962
'Dipeptoids': From the Chemical Structure of the Endogenous Peptide to the Design of Peptidomimetics
Autor:
Mercedes Martín-Martínez, Rosario Patiño-Molina, Rosario González-Muñiz, M. Teresa García-López
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 4:669-680
The present review details the rational multi-step process followed for the discovery of a family of non-peptide CCK receptor ligands ("dipeptoids"), starting from the structure of the endogenous peptide, CCK(8). Emphasis will be made on the N- and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9c5258395f868600c55722698916920
https://doi.org/10.2174/1389557043403701
https://doi.org/10.2174/1389557043403701
Autor:
Rosario González-Muñiz, Mercedes Martín-Martínez, María Teresa García-López, Rosario Patiño-Molina, Rosario Herranz
Publikováno v:
Letters in Peptide Science. 7:143-149
β-Keto esters derived from dipeptides are prepared by application of common methodologies employed for the synthesis of amino acid-derived β-keto esters; however, epimerization of the C-terminal residue occurred to different extents depending on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea89c6226d188a8e99f9c574b24fec9a
https://doi.org/10.1007/bf02443581
https://doi.org/10.1007/bf02443581
Publikováno v:
Tetrahedron. 55:15001-15010
The stereoselective generation of 3,5-disubstituted and 3,5,6-trisubstituted 2-oxopiperazine derivatives can be accomplished by intramolecular reductive amination of β-keto esters derived from Z-Xaa-Gly-OH and Z-Xaa-Yaa- OH dipeptides, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4976d636e0f69b8682542bcc81d1ea6
https://doi.org/10.1016/s0040-4020(99)00957-6
https://doi.org/10.1016/s0040-4020(99)00957-6
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::011ccda2d191774fb13c3cff2ef21e76
https://doi.org/10.1002/chin.200013155
https://doi.org/10.1002/chin.200013155
'Dipeptoids': from the chemical structure of the endogenous peptide to the design of peptidomimetics
Autor:
Mercedes, Martín-Martínez, Rosario, Patiño-Molina, M Teresa, García-López, Rosario, González-Muñiz
Publikováno v:
Mini reviews in medicinal chemistry. 4(6)
The present review details the rational multi-step process followed for the discovery of a family of non-peptide CCK receptor ligands ("dipeptoids"), starting from the structure of the endogenous peptide, CCK(8). Emphasis will be made on the N- and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7fdb0d3f3bba385a25af662ba5b984d
https://pubmed.ncbi.nlm.nih.gov/15279601
https://pubmed.ncbi.nlm.nih.gov/15279601
Autor:
M. T. Garcia‐Lopez, Miriam Latorre, Rosario Herranz, I. Gomez‐Monterrey, del Río J, Rosario Patiño-Molina, Rosario González-Muñiz, J M Bartolomé-Nebreda, Edurne Cenarruzabeitia, Mercedes Martín-Martínez
To establish structure-activity relationships a new series of analogues of the highly potent and selective CCK(1) receptor antagonist (4aS,5R)-2-benzyl-5-(N-Boc-tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]-pyrimidine (1a) modified at N2-position o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb69e46f7f0f673a67288497b4225b5
http://hdl.handle.net/11588/145695
http://hdl.handle.net/11588/145695
