Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Rosario Osta"'
Autor:
Paula Aparicio, David Navarrete‐Villanueva, Alba Gómez‐Cabello, Tresa López‐Royo, Enrique Santamaría, Joaquín Fernández‐Irigoyen, Karina Ausín, Manuel Arruebo, Victor Sebastian, Germán Vicente‐Rodríguez, Rosario Osta, Raquel Manzano
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1883-1897 (2024)
Abstract Background Sarcopenia, the gradual and generalized loss of muscle mass and function with ageing, is one of the major health problems in older adults, given its high prevalence and substantial socioeconomic implications. Despite the extensive
Externí odkaz:
https://doaj.org/article/d1f9518606374239b3f7f8bf3ae2919c
Autor:
Tresa López-Royo, Laura Moreno-Martínez, Pilar Zaragoza, Alberto García-Redondo, Raquel Manzano, Rosario Osta
Publikováno v:
Open Biology, Vol 14, Iss 10 (2024)
Amyotrophic lateral sclerosis (ALS) is a devastating neuromuscular disease characterized by progressive motor function and muscle mass loss. Despite extensive research in the field, the underlying causes of ALS remain incompletely understood, contrib
Externí odkaz:
https://doaj.org/article/155ecee41cca4e0990036f3e25a2158a
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 377 (2024)
Amyotrophic lateral sclerosis (ALS) that comprises sporadic (sALS) and familial (fALS) cases, is a devastating neurodegenerative disorder characterized by progressive degeneration of motor neurons, leading to muscle atrophy and various clinical manif
Externí odkaz:
https://doaj.org/article/e578f381a68d465a9fcba693464bb08e
Autor:
Daniel Borrego-Hernández, Juan Francisco Vázquez-Costa, Raúl Domínguez-Rubio, Laura Expósito-Blázquez, Elena Aller, Ariadna Padró-Miquel, Pilar García-Casanova, María J. Colomina, Cristina Martín-Arriscado, Rosario Osta, Pilar Cordero-Vázquez, Jesús Esteban-Pérez, Mónica Povedano-Panadés, Alberto García-Redondo
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 356 (2024)
Intermediate CAG expansions in the gene ataxin-2 (ATXN2) are a known risk factor for ALS, but little is known about their role in FTD risk. Moreover, their contribution to the risk and phenotype of patients might vary in populations with different ge
Externí odkaz:
https://doaj.org/article/6e52c9e0d7754724821309829d1f7d65
Analysis of Plasma-Derived Exosomal MicroRNAs as Potential Biomarkers for Canine Idiopathic Epilepsy
Autor:
Mireya García-Gracia, Laura Moreno-Martinez, Adelaida Hernaiz, Sebastián Usón, Jon Moral, David Sanz-Rubio, Pilar Zaragoza, Jorge Palacio, Belén Rosado, Rosario Osta, Sylvia García-Belenguer, Inmaculada Martín Burriel
Publikováno v:
Animals, Vol 14, Iss 2, p 252 (2024)
Epilepsy is one of the most prevalent complex neurological diseases in both the canine and human species, with the idiopathic form as its most common diagnosis. MicroRNAs (miRNAs) are small, noncoding RNA molecules that play a role in gene regulation
Externí odkaz:
https://doaj.org/article/41687da3f2df49769aa8ebac7c4e8e2f
Autor:
Anna Martínez-Muriana, Diego Pastor, Renzo Mancuso, Amaya Rando, Rosario Osta, Salvador Martínez, Rubèn López-Vales, Xavier Navarro
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-11 (2020)
Abstract Background The simultaneous contribution of several etiopathogenic disturbances makes amyotrophic lateral sclerosis (ALS) a fatal and challenging disease. Here, we studied two different cell therapy protocols to protect both central and peri
Externí odkaz:
https://doaj.org/article/8d33161732da499ba5e50cfa37ffd723
Autor:
Ana C Calvo, Laura Moreno, Leticia Moreno, Janne M Toivonen, Raquel Manzano, Nora Molina, Miriam de la Torre, Tresa López, Francisco J Miana-Mena, María J Muñoz, Pilar Zaragoza, Pilar Larrodé, Alberto García-Redondo, Rosario Osta
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 6, Pp 988-995 (2020)
Among collagen members in the collagen superfamily, type XIX collagen has raised increasing interest in relation to its structural and biological roles. Type XIX collagen is a Fibril-Associated Collagen with Interrupted Triple helices member, one mai
Externí odkaz:
https://doaj.org/article/318993b623d4493aaa934b34375181b7
Autor:
Guillem Mòdol-Caballero, Mireia Herrando-Grabulosa, Belén García-Lareu, Neus Solanes, Sergi Verdés, Rosario Osta, Isaac Francos-Quijorna, Rubèn López-Vales, Ana Cristina Calvo, Assumpció Bosch, Xavier Navarro
Publikováno v:
Neurobiology of Disease, Vol 137, Iss , Pp 104793- (2020)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder affecting motoneurons (MNs), with no effective treatment currently available. The molecular mechanisms that are involved in MN death are complex and not fully understood, with partia
Externí odkaz:
https://doaj.org/article/b575c34266b74f7da9212ad1f511120c
Autor:
Amaya Rando, Diego Pastor, Mari Carmen Viso-León, Anna Martínez, Raquel Manzano, Xavier Navarro, Rosario Osta, Salvador Martínez
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscle weakness, paralysis and death. There is no effective treatment for ALS and stem cell therapy has arisen as a potential therape
Externí odkaz:
https://doaj.org/article/14b3ec59f88a40beb9ef009ee12b7056
Autor:
Tresa López-Royo, Víctor Sebastián, Laura Moreno-Martínez, Laura Uson, Cristina Yus, Teresa Alejo, Pilar Zaragoza, Rosario Osta, Manuel Arruebo, Raquel Manzano
Publikováno v:
Nanomaterials, Vol 11, Iss 10, p 2723 (2021)
The development of new gene-editing technologies has fostered the need for efficient and safe vectors capable of encapsulating large nucleic acids. In this work we evaluate the synthesis of large-size plasmid-loaded PLGA nanoparticles by double emuls
Externí odkaz:
https://doaj.org/article/7280452fcab64166b47917b4fba12ee7