Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Rosario Maroto"'
Autor:
Ted G. Graber, Rosario Maroto, Jill K. Thompson, Steven G. Widen, Zhaohui Man, Megan L. Pajski, Blake B. Rasmussen
Publikováno v:
Journal of Ageing and Longevity, Vol 3, Iss 2, Pp 159-178 (2023)
One inevitable consequence of aging is the gradual deterioration of physical function and exercise capacity, driven in part by the adverse effect of age on muscle tissue. We hypothesized that relationships exist between age-related differentially exp
Externí odkaz:
https://doaj.org/article/1b08a17837f44e75b8e7572f5c2f07ce
Autor:
Rosario Maroto, Yingxin Zhao, Mohammad Jamaluddin, Vsevolod L. Popov, Hongwang Wang, Madumali Kalubowilage, Yueqing Zhang, Jonathan Luisi, Hong Sun, Christopher T. Culbertson, Stefan H. Bossmann, Massoud Motamedi, Allan R. Brasier
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
Background: Extracellular vesicles contain biological molecules specified by cell-type of origin and modified by microenvironmental changes. To conduct reproducible studies on exosome content and function, storage conditions need to have minimal impa
Externí odkaz:
https://doaj.org/article/6ddb96dc48e0405ea2ade86b9765024f
Autor:
Rasmussen, Ted G. Graber, Rosario Maroto, Jill K. Thompson, Steven G. Widen, Zhaohui Man, Megan L. Pajski, Blake B.
Publikováno v:
Journal of Ageing and Longevity; Volume 3; Issue 2; Pages: 159-178
One inevitable consequence of aging is the gradual deterioration of physical function and exercise capacity, driven in part by the adverse effect of age on muscle tissue. We hypothesized that relationships exist between age-related differentially exp
Autor:
Sanjay Kumar, Rosario Maroto, Simon Powell, Felix Margadant, Brandon Blair, Blake B. Rasmussen, Michael Sheetz
Accumulation of senescent cells in tissue and organs leads to aging abnormalities. Rejuvenating senescent cells provides a strategy to ameliorate aging. We report here that low frequency ultrasound (LFU) rejuvenates senescent cells causing growth and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007e551aff4744f219307bafb14b0a0b
https://doi.org/10.1101/2022.12.08.519320
https://doi.org/10.1101/2022.12.08.519320
Publikováno v:
J Gerontol A Biol Sci Med Sci
The inability of older adults to maintain independence is a consequence of sarcopenia and frailty. In order to identify the molecular mechanisms responsible for decreased physical function, it will be critical to utilize a small animal model. The mai
Autor:
Christopher S. Fry, Stanley J. Watowich, Camille R. Brightwell, Stanton F. McHardy, Ted G. Graber, Hua Yu Leo Wang, Rosario Maroto, Harshini Neelakantan, John Papaconstantinou
Publikováno v:
Biochem Pharmacol
Aging is accompanied by progressive declines in skeletal muscle mass and strength and impaired regenerative capacity, predisposing older adults to debilitating age-related muscle deteriorations and severe morbidity. Muscle stem cells (muSCs) that pro
Autor:
Maki Wakamiya, Camille R. Brightwell, Ted G. Graber, Tatiana Moro, Blake B. Rasmussen, Christopher S. Fry, Rosario Maroto, Craig Porter, Nisha Bhattarai
Publikováno v:
Journal of Biological Chemistry. 294:4091-4102
mTORC1 regulates protein synthesis and in turn is regulated by growth factors, energy status, and amino acid availability. In kidney cell (HEK293-T) culture, the GAP activity toward RAG (GATOR1) protein complex suppresses activation of the RAG A/B–
Autor:
Gracie Vargas, Mohammad Jamaluddin, Erik Rytting, Julia Litvinov, Igor Patrikeev, Bill T. Ameredes, Lorenzo Ochoa, Massoud Motamedi, Jia Zhou, Rosario Maroto, Zhiqing Liu, Bing Tian, Allan R. Brasier
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 60:68-83
NF-κB/RelA triggers innate inflammation by binding to bromodomain-containing protein 4 (BRD4), an atypical histone acetyltransferase (HAT). Although RelA·BRD4 HAT mediates acute neutrophilic inflammation, its role in chronic and functional airway r
Publikováno v:
Medicine & Science in Sports & Exercise. 52:85-85
Publikováno v:
Journal of proteome research. 16(8)
Protein tyrosine nitration by oxidative and nitrate stress is important in the pathogenesis of many inflammatory or aging-related diseases. Mass spectrometry analysis of protein nitrotyrosine is very challenging because the non-nitrated peptides supp