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Akademický článek

Determinants of clinical outcome in patients with moderate/severe Graves' orbitopathy undergoing treatment with parenteral glucocorticoids: a retrospective study

Autor: Rosario Le Moli, Adriano Naselli, Gabriele Costanzo, Tommaso Piticchio, Dario Tumino, Gabriella Pellegriti, Francesco Frasca, Antonino Belfiore

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

BackgroundGraves' orbitopathy (GO) occurs in approximately 25-40% of patients with Graves' disease (GD). High levels of anti-thyrotropin receptor antibodies (TRAbs), smoking habit, sex, older age, longer duration and amount of hyperthyroidism or hypo

Externí odkaz: https://doaj.org/article/a18573da65d14e0dacba69e4b1c93e82

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El Rosario le apuesta a la formación de las futuras generaciones de investigadores del país

Autor: Reyes, Carlos Roberto, Restrepo-Abondano, Jose-Manuel

Publikováno v: Advances in Science; Núm. 1 (2017); 10-13
Divulgación Científica; Núm. 1 (2017); 10-13
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

La universidad creó un programa de investigación formativa que arranca desde el pregrado y donde los jóvenes tienen la posibilidad de construir y desarrollar un proyecto de vida académica. The University set up a research training program thatsta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::42bca858ed86eb600dd21dd88c18bdc1
http://repository.urosario.edu.co/handle/10336/17879

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Akademický článek

Levothyroxine therapy, calculated deiodinases activity and basal metabolic rate in obese or nonobese patients after total thyroidectomy for differentiated thyroid cancer, results of a retrospective observational study

Autor: Rosario Le Moli, Pasqualino Malandrino, Marco Russo, Dario Tumino, Tommaso Piticchio, Adriano Naselli, Valentina Rapicavoli, Antonino Belfiore, Francesco Frasca

Publikováno v: Endocrinology, Diabetes & Metabolism, Vol 6, Iss 2, Pp n/a-n/a (2023)

Abstract Introduction Therapy for hypothyroid obese patients is still under definition since the thyrotropin‐stimulating hormone (TSH) level is a less reliable marker of euthyroidism than nonobese patients. Indeed, TSH levels positively correlate w

Externí odkaz: https://doaj.org/article/e85cfec731ac49dcba86664430a004ee

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Akademický článek

Inflammasome activation as a link between obesity and thyroid disorders: Implications for an integrated clinical management

Autor: Rosario Le Moli, Veronica Vella, Dario Tumino, Tommaso Piticchio, Adriano Naselli, Antonino Belfiore, Francesco Frasca

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Obesity is strongly associated with chronic low-grade inflammation. Obese patients have an increased risk to develop thyroid autoimmunity and to became hypothyroid, suggesting a pathogenetic link between obesity, inflammation and autoimmunity. Moreov

Externí odkaz: https://doaj.org/article/2f3c9438959e4b399da0b9fd79030f20

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Akademický článek

IGF2: A Role in Metastasis and Tumor Evasion from Immune Surveillance?

Autor: Antonino Belfiore, Rosaria Valentina Rapicavoli, Rosario Le Moli, Rosamaria Lappano, Andrea Morrione, Ernestina Marianna De Francesco, Veronica Vella

Publikováno v: Biomedicines, Vol 11, Iss 1, p 229 (2023)

Insulin-like growth factor 2 (IGF2) is upregulated in both childhood and adult malignancies. Its overexpression is associated with resistance to chemotherapy and worse prognosis. However, our understanding of its physiological and pathological role i

Externí odkaz: https://doaj.org/article/41581224fb9a40b6886504554358eeac

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Akademický článek

Evidence That Baseline Levels of Low-Density Lipoproteins Cholesterol Affect the Clinical Response of Graves’ Ophthalmopathy to Parenteral Corticosteroids

Autor: Adriano Naselli, Diletta Moretti, Concetto Regalbuto, Maria Luisa Arpi, Fabrizio Lo Giudice, Francesco Frasca, Antonino Belfiore, Rosario Le Moli

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

BackgroundHigh dose intravenous glucocorticoid (ivGC) therapy is the first line treatment in moderate to severe Graves’ ophthalmopathy (GO) and is associated with a clinical response rate ranging from 50% to 80%. Recently, a positive correlation be

Externí odkaz: https://doaj.org/article/eec3b6e7137a475584b29c2c3d2d889d

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Akademický článek

Corticosteroid Pulse Therapy for Graves' Ophthalmopathy Reduces the Relapse Rate of Graves' Hyperthyroidism

Autor: Rosario Le Moli, Pasqualino Malandrino, Marco Russo, Fabrizio Lo Giudice, Francesco Frasca, Antonino Belfiore, Riccardo Vigneri

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

Background: A course of anti-thyroid drugs (ATD) is the most common first line treatment for Graves' hyperthyroidism. However, hyperthyroidism relapse is frequent (30–70%). Due to the autoimmune nature of Graves' disease, the immunosuppressive trea

Externí odkaz: https://doaj.org/article/39f6c36c1a27467f88cbef8f4a9b8cad

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