Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Rosario González‐Muñiz"'
Autor:
Tania Ciaglia, Vincenzo Vestuto, Alessia Bertamino, Rosario González-Muñiz, Isabel Gómez-Monterrey
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
The transient melastatin receptor potential (TRPM) ion channel subfamily functions as cellular sensors and transducers of critical biological signal pathways by regulating ion homeostasis. Some members of TRPM have been cloned from cancerous tissues,
Externí odkaz:
https://doaj.org/article/c4bca2cd14994b09b989c3cac6fc6245
Publikováno v:
Molecules, Vol 26, Iss 2, p 445 (2021)
Cyclic and macrocyclic peptides constitute advanced molecules for modulating protein–protein interactions (PPIs). Although still peptide derivatives, they are metabolically more stable than linear counterparts, and should have a lower degree of fle
Externí odkaz:
https://doaj.org/article/40f6c95bd77f4877a0fd4599b3bf9d1e
Autor:
María Jesús Pérez de Vega, Silvia Moreno-Fernández, Gloria María Pontes-Quero, María González-Amor, Blanca Vázquez-Lasa, Beatriz Sabater-Muñoz, Ana M. Briones, María R. Aguilar, Marta Miguel, Rosario González-Muñiz
Publikováno v:
Antioxidants, Vol 9, Iss 9, p 787 (2020)
Antioxidant compounds, including polyphenols, have therapeutic effects because of their anti-inflammatory, antihypertensive, antithrombotic and antiproliferative properties. They play important roles in protecting the cardiovascular and neurological
Externí odkaz:
https://doaj.org/article/6a1a989cc2114d189890facbd7df15ba
Autor:
Rosario González-Muñiz, Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Fernando Albericio, Laura Zaccaro, Miriam Royo, Mª Teresa García-López, Mª Jesús Pérez de Vega
Publikováno v:
Molecules, Vol 15, Iss 7, Pp 4924-4933 (2010)
Trp(Nps)-Lys-NH2 derivatives, bearing alkyl or guanidine groups either at the N–terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.
Externí odkaz:
https://doaj.org/article/93fb60875f7140c5808ab0f070b3fc65
Autor:
Beatriz Balsera, M. Ángeles Bonache, Marie Reille-Seroussi, Nathalie Gagey-Eilstein, Michel Vidal, Rosario González-Muñiz, María Jesús Pérez de Vega
Publikováno v:
Molecules, Vol 22, Iss 11, p 1846 (2017)
The interaction between vascular endothelial growth factor (VEGF) and its receptors (VEGFR) has important implications in angiogenesis and cancer, which moved us to search for peptide derivatives able to block this protein–protein interaction. In a
Externí odkaz:
https://doaj.org/article/b5119049a937466c95286b63caa9caaf
Autor:
Paula Pérez-Faginas, M Teresa Aranda, M Teresa García-López, Lourdes Infantes, Asia Fernández-Carvajal, José Manuel González-Ros, Antonio Ferrer-Montiel, Rosario González-Muñiz
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53231 (2013)
1,2-Diamine derivatives are valuable building blocks to heterocyclic compounds and important precursors of biologically relevant compounds. In this respect, amino acid-derived β-keto esters are a suitable starting point for the synthesis of β,γ-di
Externí odkaz:
https://doaj.org/article/7dfdae62614e42498e3fa7f83dc0793c
Autor:
Felipe Luis Pérez-Gordillo, Natalia Serrano-Morillas, Luz Marina Acosta-García, María Teresa Aranda, Daniela Passeri, Roberto Pellicciari, María Jesús Pérez de Vega, Rosario González-Muñiz, Diego Alvarez de la Rosa, Mercedes Martín-Martínez
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2439
Volume 24
Issue 3
Pages: 2439
The mineralocorticoid receptor (MR) belongs to the steroid receptor subfamily of nuclear receptors. MR is a transcription factor key in regulating blood pressure and mineral homeostasis. In addition, it plays an important role in a broad range of bio
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society.
The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still affecting people worldwide. Despite the good degree of immunological protection achieved through vaccination, there are still severe cases tha
Autor:
Rosario González-Muñiz, Carmen Cuevas, M. Angeles Bonache, Roberto de la Torre Martínez, Sara González-Rodríguez, Ana María Roa, Alicia Medina, Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Gregorio Fernández-Ballester, Cristina Martín-Escura, Andrés Francesch
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
The cool sensor transient receptor potential melastatin channel 8 (TRPM8) is highly expressed in trigeminal and dorsal root ganglia, playing a key role in cold hypersensitivity associated to different peripheral neuropathies. Moreover, these channels
Autor:
Cristina Martín-Escura, Alicia Medina-Peris, Luke A. Spear, Roberto de la Torre Martínez, Luis A. Olivos-Oré, María Victoria Barahona, Sara González-Rodríguez, Gregorio Fernández-Ballester, Asia Fernández-Carvajal, Antonio R. Artalejo, Antonio Ferrer-Montiel, Rosario González-Muñiz
Publikováno v:
E-Prints Complutense. Archivo Institucional de la UCM
Universitad de Lleida
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2692
Digital.CSIC. Repositorio Institucional del CSIC
instname
WOS:000775933300001
Universitad de Lleida
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2692
Digital.CSIC. Repositorio Institucional del CSIC
instname
WOS:000775933300001
Transient receptor potential melastatin subtype 8 (TRPM8) is a cation channel extensively expressed in sensory neurons and implicated in different painful states. However, the effectiveness of TRPM8 modulators for pain relief is still a matter of dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be9244327ac80d3f36da21b0788d987
http://hdl.handle.net/10261/269728
http://hdl.handle.net/10261/269728