Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rosario Brieva"'
Publikováno v:
WOS:000763332100001
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Regional Government of Asturias (FICYT) [SV-PA-21-AYUD/2021/51542]; University of Oviedo
Publikováno v:
Green Chemistry. 19:436-446
The lipase catalyzed resolution of several cis and trans 3-aminopyridinylmethyl-4-hydroxypyrrolidines by acylation or hydrolysis has been studied. Some of these pryrrolidines are precursors in the synthesis of selective nNOS inhibitors; for this purp
Publikováno v:
Tetrahedron. 71:6907-6912
Optically pure orthogonally protected trans-3-amino-4-hydroxypiperidines have been easily prepared from (±)-1-benzyl-3,4-epoxypiperidine. The key steps are a regioselective epoxide ring-opening with diallylamine and the enzymatic resolution of the r
Publikováno v:
Organicbiomolecular chemistry. 15(24)
A chemoenzymatic approach for the synthesis of optically active 4-(3-acetoxyphenyl)-5-(alkoxycarbonyl)-6-methyl-3,4-dihydropyridin-2-ones (3,4-DHP-2-ones) and their hydroxyphenyl derivatives has been developed, the key step being a Candida rugosa lip
Autor:
Jesús A. Rodríguez-Rodríguez, Francisca Rebolledo, F. Javier Quijada, Rosario Brieva, Vicente Gotor
Publikováno v:
Tetrahedron. 69:5407-5412
Several orthogonally protected racemic trans -3-amino-4-hydroxypyrrolidines have been easily prepared from N -Cbz-3,4-epoxypyrrolidine. Resolution of each racemic compound was accomplished by means of lipase-catalyzed aminolysis, transesterification
Publikováno v:
Tetrahedron: Asymmetry. 24:694-698
The lipase catalyzed resolution of trans -3,4-tetrahydrofuran and pyrrolidine bromohydrins by acylation or hydrolysis of their acylated derivatives has been studied. For both heterocycles, the best enantioselectivity was obtained using Candida antarc
Publikováno v:
Tetrahedron: Asymmetry. 22:1218-1224
The enantioselective preparation of both enantiomers of the benzo-fused cyanohydrin derived from α-tetralone via lipase catalyzed processes is described. The ( S )-enantiomer has been obtained as the remaining substrate in the CAL-A catalyzed aminol
Publikováno v:
Tetrahedron. 66:6789-6796
Enzymatic acylations and alcoxycarbonylations of cis- and trans-3,4-dihydroxypyrrolidines and hydrolysis of their diacylated or dialcoxycarbonylated derivatives have been studied. High enantioselectivity is obtained using Candida antarctica lipase B
Publikováno v:
Tetrahedron: Asymmetry. 19:1684-1688
Enzymatic acylations and alkoxycarbonylations of cis- and trans-3,4-dihydroxytetrahydrofuran and hydrolysis of their diacetylated and dialkoxycarbonylated derivatives have been studied. High enantioselectivity is obtained using Pseudomonas cepacia li
Publikováno v:
Tetrahedron: Asymmetry. 18:994-1002
Enantiomerically pure 1-cycloalkyl-1-hydroxy-1-phenylcyanohydrins, key precursors in the synthesis of ( S )-oxybutynin and other antimuscarinic agents, have been successfully prepared via lipase-catalyzed kinetic resolutions. Pseudomonas cepacia and