Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Rosario AM"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Myelofibrosis (MF) is a complex myeloproliferative neoplasm characterized by abnormal hematopoietic stem cell proliferation and subsequent bone marrow (BM) fibrosis. First documented in the late 19th century, MF has since been extensively st
Externí odkaz:
https://doaj.org/article/b3fd08c1e5694a448164f5ef797abca5
Autor:
Alessio Canovai, James R. Tribble, Melissa Jöe, Daniela Y. Westerlund, Rosario Amato, Ian A. Trounce, Massimo Dal Monte, Pete A. Williams
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Retinal ganglion cells are highly metabolically active requiring strictly regulated metabolism and functional mitochondria to keep ATP levels in physiological range. Imbalances in metabolism and mitochondrial mechanisms can be sufficient to
Externí odkaz:
https://doaj.org/article/9b0fb1fc29404f1ebda176ae9e7a591f
Autor:
Veronica Rodriguez Fernandez, Rosario Amato, Simona Piaggi, Barbara Pinto, Giovanni Casini, Fabrizio Bruschi
Publikováno v:
Pathogens, Vol 13, Iss 8, p 701 (2024)
Ocular toxoplasmosis is the most prevalent clinical manifestation of T. gondii infection, which causes irreversible retinal damage. Different experimental models have been developed to study this pathology. In the present study, a new, ex vivo model
Externí odkaz:
https://doaj.org/article/e0dde58c4d1747319da8e8777b565c58
Autor:
Giuseppina Nicolini, Giovanni Casini, Chiara Posarelli, Rosario Amato, Matteo Lulli, Silvana Balzan, Francesca Forini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7364 (2024)
Thyroid Hormones (THs) play a central role in the development, cell growth, differentiation, and metabolic homeostasis of neurosensory systems, including the retina. The coordinated activity of various components of TH signaling, such as TH receptors
Externí odkaz:
https://doaj.org/article/51fb6a04c0734625901efa33fccea3ba
Autor:
Tiziana Fioretti, Fabrizio Martora, Ilaria De Maggio, Adelaide Ambrosio, Carmelo Piscopo, Sabrina Vallone, Felice Amato, Diego Passaro, Fabio Acquaviva, Francesca Gaudiello, Daniela Di Girolamo, Valeria Maiolo, Federica Zarrilli, Speranza Esposito, Giuseppina Vitiello, Luigi Auricchio, Elena Sammarco, Daniele De Brasi, Roberta Petillo, Antonella Gambale, Fabio Cattaneo, Rosario Ammendola, Paola Nappa, Gabriella Esposito
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1112 (2024)
Inherited ichthyoses are a group of clinically and genetically heterogeneous rare disorders of skin keratinization with overlapping phenotypes. The clinical picture and family history are crucial to formulating the diagnostic hypothesis, but only the
Externí odkaz:
https://doaj.org/article/cf770a14d73143508ed72d9485ac9251
Autor:
Tiziana Pecchillo Cimmino, Carolina Punziano, Iolanda Panico, Zeudi Petrone, Myrhiam Cassese, Raffaella Faraonio, Vincenza Barresi, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 552 (2024)
Cancer cells exhibit high levels of oxidative stress and consequently require a high amount of cysteine for glutathione synthesis. Solute Carrier Family 7 Member 11 (SLC7A11), or xCT, mediates the cellular uptake of cystine in exchange for intracellu
Externí odkaz:
https://doaj.org/article/9ea3c1ceafdd4477a13ca3f664c40436
Autor:
Tiziana Pecchillo Cimmino, Ester Pagano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
The human formyl-peptide receptor 2 (FPR2) is activated by an array of ligands. By phospho-proteomic analysis we proved that FPR2 stimulation induces redox-regulated phosphorylation of many proteins involved in cellular metabolic processes. In this s
Externí odkaz:
https://doaj.org/article/7b18e3c4ca0f4f3fa01b364e3c354996
Autor:
Alberto Melecchi, Rosario Amato, Massimo Dal Monte, Dario Rusciano, Paola Bagnoli, Maurizio Cammalleri
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionMuch interest has been addressed to antioxidant dietary supplements that are known to lower the risk of developing glaucoma or delay its progression. Among them, niacin and citicoline protect retinal ganglion cells (RGCs) from degeneratio
Externí odkaz:
https://doaj.org/article/efe3fbfdd5f44d749632d04b2ca4c0f0
Autor:
Carolina Brescia, Vincenzo Dattilo, Lucia D’Antona, Emanuela Chiarella, Rossana Tallerico, Salvatore Audia, Valentina Rocca, Rodolfo Iuliano, Francesco Trapasso, Nicola Perrotti, Rosario Amato
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Th17+ arrangement is critical for orchestrating both innate and acquired immune responses. In this context, the serum and glucocorticoid regulated kinase 1 (SGK1) exerts a key role in the governance of IL-23R-dependent Th17+ maturation, through t
Externí odkaz:
https://doaj.org/article/7f096d7da09943c9bf2415dd907f4548
Autor:
Tiziana Pecchillo Cimmino, Iolanda Panico, Simona Scarano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 220 (2024)
Phospholipases (PL) A2 catalyzes the hydrolysis of membrane phospholipids and mostly generates arachidonic acid (AA). The enzyme 5-lipoxygenase (5-LOX) can metabolize AA to obtain inflammatory leukotrienes, whose biosynthesis highly depends on cPLA2
Externí odkaz:
https://doaj.org/article/0bae0b4f317b4625ac7780321546336b