Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rosaria Chiang"'
Autor:
Julia Arand, H Rosaria Chiang, David Martin, Michael P Snyder, Julien Sage, Renee A Reijo Pera, Mark Wossidlo
Publikováno v:
EMBO reports. 23(2)
Mammalian development begins in transcriptional silence followed by a period of widespread activation of thousands of genes. DNA methylation reprogramming is integral to embryogenesis and linked to Tet enzymes, but their function in early development
Autor:
Morteza Roodgar, Fabian P. Suchy, Lan H. Nguyen, Vivek K. Bajpai, Rahul Sinha, Jose G. Vilches-Moure, Kevin Van Bortle, Joydeep Bhadury, Ahmed Metwally, Lihua Jiang, Ruiqi Jian, Rosaria Chiang, Angelos Oikonomopoulos, Joseph C. Wu, Irving L. Weissman, Joseph L. Mankowski, Susan Holmes, Kyle M. Loh, Hiromitsu Nakauchi, Catherine A. VandeVoort, Michael P. Snyder
Publikováno v:
Cell Rep
Cell reports, vol 40, iss 9
Cell reports, vol 40, iss 9
As our closest living relatives, non-human primates uniquely enable explorations of human health, disease, development, and evolution. Considerable effort has thus been devoted to generating induced pluripotent stem cells (iPSCs) from multiple non-hu
Autor:
Fang Fang, Benjamin Angulo, Renee A. Reijo Pera, Ninuo Xia, Pengbo Zhang, James G. Taylor, Zhengyuan Wang, Rosaria Chiang, Megan Rothstein
Publikováno v:
Scientific Reports
Generation of induced dopaminergic (iDA) neurons may provide a significant step forward towards cell replacement therapy for Parkinson’s disease (PD). To study and compare transcriptional programs of induced cells versus primary DA neurons is a pre
Autor:
H. Rosaria Chiang, Kyle Kai-How Farh, Alena Shkumatava, Chanseok Shin, David P. Bartel, Jin Wu Nam
Publikováno v:
PMC
Most metazoan microRNA (miRNA) target sites have perfect pairing to the seed region, located near the miRNA 5′ end. Although pairing to the 3′ region sometimes supplements seed matches or compensates for mismatches, pairing to the central region
Autor:
H. Rosaria Chiang, David P. Bartel, Andrew Grimson, Nicole King, Bryony Fahey, Bernard M. Degnan, Mansi Srivastava, Ben J. Woodcroft, Daniel S. Rokhsar
Publikováno v:
Nature. 455:1193-1197
In bilaterian animals, such as humans, flies and worms, hundreds of microRNAs (miRNAs), some conserved throughout bilaterian evolution, collectively regulate a substantial fraction of the transcriptome. In addition to miRNAs, other bilaterian small R
Autor:
Shenghua Duan, Daniel A. Chaves, Noah Fahlgren, Darryl Conte, Pedro J. Batista, Craig C. Mello, J. Graham Ruby, Kristin D. Kasschau, Shujun Luo, James C. Carrington, David P. Bartel, H. Rosaria Chiang, Julie M. Claycomb, Jessica J. Vasale, Gary P. Schroth, Weifeng Gu
Publikováno v:
Molecular Cell. 31(1):67-78
In metazoans Piwi-related Argonaute proteins have been linked to germ-line maintenance, and to a class of germ-line enriched small RNAs termed piRNAs. Here we show that an abundant class of 21-nucleotide small RNAs (21U-RNAs) are expressed in the C.
Publikováno v:
Scientific Reports
Turner syndrome is caused by complete or partial loss of the second sex chromosome and is characterized by spontaneous fetal loss in >90% of conceptions. Survivors possess an array of somatic and germline clinical characteristics. Induced pluripotent
Autor:
J. Graham Ruby, Lori W. Schoenfeld, Noah Spies, Joshua E. Babiarz, Gary P. Schroth, Chad Nusbaum, Vincent C. Auyeung, Wendy K. Johnston, David P. Bartel, Daehyun Baek, Shujun Luo, Robert Blelloch, H. Rosaria Chiang, Carsten Russ
MicroRNAs (miRNAs) are small regulatory RNAs that derive from distinctive hairpin transcripts. To learn more about the miRNAs of mammals, we sequenced 60 million small RNAs from mouse brain, ovary, testes, embryonic stem cells, three embryonic stages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553ed129a9ae2ea36709ad1b509c2b6d
https://europepmc.org/articles/PMC2867214/
https://europepmc.org/articles/PMC2867214/
Autor:
Monty Krieger, Yumiko Toyama, Rostislav Medvid, H. Rosaria Chiang, Sumeet Gupta, Robert Blelloch, Ronglih Liao, Ferenc Reinhardt, Prakash K. Rao, Michael Bauer, Harvey F. Lodish, Rudolf Jaenisch
Publikováno v:
PMC
Rationale: Heart failure is a deadly and devastating disease that places immense costs on an aging society. To develop therapies aimed at rescuing the failing heart, it is important to understand the molecular mechanisms underlying cardiomyocyte stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5a9c921cf5bc5cd489928804250915
https://orcid.org/0000-0003-4541-5181
https://orcid.org/0000-0003-4541-5181