Inhibition of a vascular ocular tumor growth by IL-12 gene transfer

Autor: Adriana Albini, Raffaella Dell'Eva, Gianfranco Fassina, Rosaria Cammarota, Roberta Venè, Douglas M. Noonan, Massimo Barberis, Massimo Nicolò

Publikováno v: Clinical & experimental metastasis 24 (2007): 485–493.
info:cnr-pdr/source/autori:Albini A. 1, Fassina G. 2, Nicolò M. 3, Dell'eva R. 4, Vené R. 5, Cammarota R. 1, Barberis M. 1, Noonan D.M. 6/titolo:Inhibition of a vascular ocular tumor growth by IL-12 gene transfer./doi:/rivista:Clinical & experimental metastasis/anno:2007/pagina_da:485/pagina_a:493/intervallo_pagine:485–493/volume:24

Ocular tumors such as retinoblastoma and uveal melanoma have devastating effects on vision. Patients with uveal melanoma also have low 5-year survival rates, thus new therapeutic modalities are necessary. As both retinoblastoma and uveal melanoma are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c1184f6f80fed7b4b2cf960433b547
https://doi.org/10.1007/s10585-007-9085-7

The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker

Autor: Giuseppina Pennesi, Eraldo O. Bucci, Massimo Barberis, Luigi Laghi, Cecilia Garlanda, Fausto Sessa, Ornella Gottardi, Douglas M. Noonan, Valentina Bertolini, Adriana Albini, Rosaria Cammarota

Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, Vol 8, Iss 1, p 112 (2010)

Background Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is associated with cancer progression and angiogenesis, we investigated expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ce18ff7d88517f5f5b5bc7a086d032
https://doi.org/10.1186/1479-5876-8-112

Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention

Autor: Douglas M. Noonan, Giuseppina Pennesi, Adriana Albini, Francesco Donatelli, Rosaria Cammarota, Silvio De Flora

Publikováno v: JNCI Journal of the National Cancer Institute

Due to the aging of the populations of developed countries and a common occurrence of risk factors, it is increasingly probable that a patient may have both cancer and cardiovascular disease. In addition, cytotoxic agents and targeted therapies used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ef6efff73b3193177a89751c223678
http://hdl.handle.net/11567/216520

Anti-angiogenic activity of a novel class of chemopreventive compounds: oleanic acid terpenoids

Autor: Ilaria, Sogno, Nicola, Vannini, Girieca, Lorusso, Rosaria, Cammarota, Douglas M, Noonan, Luca, Generoso, Michael B, Sporn, Andriana, Albini

Publikováno v: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 181

Angiogenesis is the base for solid tumour growth and dissemination, and anti-angiogenic drugs have been demonstrated to be active in clinical trials. In addition, it has become increasingly clear that inflammation is a key component in tumour insurge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06e135b74b0e3c7dffe0558a1b536093
https://pubmed.ncbi.nlm.nih.gov/19213570

TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis

Autor: Gabriella Fibbi, Rosaria Cammarota, Adriana Albini, Mario Del Rosso, Javier Dotor, Francisco Borrás-Cuesta, Anna Rita Cantelmo, Francesca Margheri, Marco Pucci, Simona Serratì

Publikováno v: Biochemical pharmacology. 77(5)

The role of transforming growth factor beta (TGFbeta) in tumor promotion and in angiogenesis is context-dependent. While TGFbeta prevents tumor growth and angiogenesis in early phases of tumor development, evidence is accumulating about its pro-angio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a1ef083226c3d8f6b21ba10f35c1c8
https://pubmed.ncbi.nlm.nih.gov/19041849