Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Rosaramicin"'
Autor:
Andrew T. McPhail, Doris P. Schumacher, Robert S. Jaret, Mohindar S. Puar, Tom Mollitor, Bernard Rosenkrantz
Publikováno v:
The Journal of Antibiotics. 45:1540-1543
The structures of two solid-state rearrangement products, A and B, of rosaramicin have been assigned on the basis of 13C NMR spectral data and a single-crystal X-ray analysis of the acetone solvate of product B.
Publikováno v:
The Journal of Antibiotics. 43:1006-1009
New 16-membered macrolide antibiotics 6108A 1 , B, C and D were isolated from the culture filtrate of a Micromonospora fastidiosus. In this paper, we describe the structure elucidation of these compounds.
Publikováno v:
Journal of chromatography. A. 812(1-2)
The following macrolide antibiotics have been covered in this review: erythromycin and its related substances, azithromycin, clarithromycin, dirithromycin, roxithromycin, flurithromycin, josamycin, rokitamycin, kitasamycin, mycinamycin, mirosamycin,
Autor:
Kohtarou Funaishi, Kenji Kawamura, Hagiwara Masayuki, Hiramatsu Muneyo, Masanori Okanish, Fumio Satoh
Publikováno v:
The Journal of antibiotics. 43(8)
Antibiotics 6108 A1, B, C and D, a new series of analogues of rosaramicin, were found together with rosaramicin, juvenimicin A4 and M-4365 A1 from the cultured broth of strain BA06108 which was assigned to be a new species of Micromonospora. 6108 A1
Publikováno v:
Médecine et Maladies Infectieuses. 13:104-110
Resume La rosaramicine est plus active que l'erythromycine sur les gonocoques, les pasteurelles, les colibacilles et la plupart des haemophilus. Elle est aussi active que la clindamycine sur Bacteroides fragilis, Clostridium perfringens, Flavobacteri
Publikováno v:
Toxicology and Applied Pharmacology. 72:195-200
Two studies were conducted to assess the toxicity of rosaramicin (a macrolide antibiotic) when given intravenously for 30 consecutive days to beagle dogs with and without a tapetum lucidum (a light reflecting structure within the choroid of the eye).
Autor:
Ustun Sunay, Bert Fraser-Reid
Publikováno v:
Tetrahedron Letters. 27:5335-5338
A pyranodisic homologation approach to the “eastern half” of rosaramicin is described. The synthetic plan calls for two one-carbon chain extensions, but these occur at “off-template” sites where asymmetric centers are neither destroyed nor cr
Publikováno v:
Drug Intelligence & Clinical Pharmacy. 14:786-812
We report the case of a possible hepatotoxic reaction in a patient receiving the investigational macrolide antibiotic, rosaramicin. The patient presented with complaints attributable to an acute cholestatic reaction with a maculopapular skin rash. Se
Autor:
R. W. Lacey
Publikováno v:
Journal of Antimicrobial Chemotherapy. 7:293-299
Autor:
Ian Maclean, M V Fast, Herbert Nsanze, P Karasira, Allan R. Ronald, Peter Piot, Frank Plummer, L J D'Costa
Publikováno v:
Scopus-Elsevier
The emergence of Haemophilus ducreyi resistant to multiple antibiotics has limited the effectiveness of sulfonamides and tetracycline for the therapy of chancroid. A randomized, double-blind study compared 10-day courses of erythromycin base (500 mg)