Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rosanne Seguin"'
Autor:
Rosanne Seguin
Publikováno v:
Oligonucleotide-Based Drugs and Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb766bf00cf3d60bce38d4322998fd39
https://doi.org/10.1002/9781119070153.ch15
https://doi.org/10.1002/9781119070153.ch15
Autor:
Rosanne Seguin
Publikováno v:
Oligonucleotide-Based Drugs and Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b83f47f5a959ad8d691e7e01b18bf12
https://doi.org/10.1002/9781119070153.ch8
https://doi.org/10.1002/9781119070153.ch8
Autor:
Nicolay Ferrari, Rosanne Seguin
A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceuti
Autor:
Rosanne Seguin, Cindy L. Berman, Jeff Tepper, Scott P. Henry, Douglas J. Kornbrust, Joy Cavagnaro
Publikováno v:
Nucleic acid therapeutics. 26(4)
This article provides an overview of the discussions held by the Immunomodulatory Subcommittee of the Oligonucleotide Safety Working Group on complement activation induced by oligonucleotides, most notably the phosphorothioate-containing oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660c05011958e42769d2c37d51195741
https://pubmed.ncbi.nlm.nih.gov/26981618
https://pubmed.ncbi.nlm.nih.gov/26981618
Publikováno v:
Future Medicinal Chemistry. 3:1647-1662
Reversing inflammatory lung disease remains the foremost challenge in treating respiratory diseases such as asthma and chronic obstructive pulmonary disease. Reducing (or modifying) the underlying inflammatory process with mono-target drugs has prove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f4d91d2399c6ce5d7f50fc021d2b81
https://doi.org/10.4155/fmc.11.108
https://doi.org/10.4155/fmc.11.108
Autor:
Alexandre Prat, Karolina Wosik, Amit Bar-Or, Ellie McCrea, Katarzyna Biernacki, Ho Jin Kim, Jack P. Antel, Rosanne Seguin, Manon Blain
Publikováno v:
Glia. 42:36-45
We assessed the effects of soluble molecules (supernatants) produced by pro- (Th1) and anti- (Th2) inflammatory T-cell lines on the capacity of adult human CNS-derived microglia to express or produce selected cell surface and soluble molecules that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a94dd17b16b8d86133cf3ba479f2d3
https://doi.org/10.1002/glia.10201
https://doi.org/10.1002/glia.10201
Autor:
Karolina Wosik, Alexandre Prat, Jack P. Antel, Zacharo Moditi, Katarzyna Biernacki, Rosanne Seguin, Ronny L. Rotondo
Publikováno v:
Journal of Neuroimmunology. 135:96-106
Blood-derived monocytic cells comprise a significant component of most inflammatory responses that occur in the CNS. We utilized human brain-derived endothelial cells (HBECs) coated membranes in Boyden chambers to assess immune function related prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1f6c9858d414bcca61f16702e22a6f
https://doi.org/10.1016/s0165-5728(02)00431-9
https://doi.org/10.1016/s0165-5728(02)00431-9
Autor:
Yassar Chakfe, Philippe Séguéla, Jack P. Antel, Céline Morissette, Danielle Malo, Duncan Henderson, Rosanne Seguin
Publikováno v:
The Journal of Neuroscience. 22:3061-3069
P2X(7) is a subtype of ATP-gated channels that is highly expressed in astrocytes, microglia, and other immune cells. Activation of P2X(7) purinoceptors by ATP or 3'-O-(4-benzoyl)-benzoyl ATP (BzATP) induces the formation of cytolytic pores and provok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701d6c507b50dd15084bad641f48ff40
https://doi.org/10.1523/jneurosci.22-08-03061.2002
https://doi.org/10.1523/jneurosci.22-08-03061.2002
Autor:
Jean Alex Steide, Rosanne Seguin, Aaron Barchowsky, Eunsung Cho, Joseph D. Schwartzman, Elijah W. Stommel, Lloyd H. Kasper
Publikováno v:
Experimental Biology and Medicine. 226:229-236
The nucleoside triphosphate hydrolase of Toxoplasma gondii is a potent apyrase that is secreted into the parasitophorous vacuole where it appears to be essentially Inactive in an oxidized form. Recent evidence shows that nucleoside triphosphate hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9d35b04f5f333a7ae5971d0c42496f
https://doi.org/10.1177/153537020122600311
https://doi.org/10.1177/153537020122600311
Autor:
Gerold Feuer, Yingxian Liu, Paul T. Massa, Vicente Planelles, Jack P. Antel, Rosanne Seguin, Stephen Wrzesinski, Edward D. Barker, Shelley Domville
Publikováno v:
AIDS Research and Human Retroviruses. 16:1771-1776
Infection with human T cell leukemia virus type 1 (HTLV-1) can result in the development of HAM/TSP, a nonfatal, chronic inflammatory disease involving neuronal degeneration and demyelination of the central nervous system. Elevated levels of the proi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ca62bea6e6c5e6e12776441e71182b
https://doi.org/10.1089/08892220050193290
https://doi.org/10.1089/08892220050193290