Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rosanne M Raftery"'
Autor:
Daniel Richard, Steven Pregizer, Divya Venkatasubramanian, Rosanne M Raftery, Pushpanathan Muthuirulan, Zun Liu, Terence D Capellini, April M Craft
Publikováno v:
eLife, Vol 12 (2023)
To address large gaps in our understanding of the molecular regulation of articular and growth plate cartilage development in humans, we used our directed differentiation approach to generate these distinct cartilage tissues from human embryonic stem
Externí odkaz:
https://doaj.org/article/366aba9684e84cb293c4642ab52790f1
Autor:
Steven Pregizer, Daniel Richard, Divya Venkatasubramanian, Rosanne M Raftery, Pushpanathan Muthuirulan, Zun Liu, Terence D Capellini, April M Craft
Publikováno v:
eLife. 12
To address large gaps in our understanding of the molecular regulation of articular and growth plate cartilage development in humans, we used our directed differentiation approach to generate these distinct cartilage tissues from human embryonic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::727f247b19dc57268e78a7f583aabcd8
https://doi.org/10.7554/elife.79925
https://doi.org/10.7554/elife.79925
Autor:
Steven Pregizer, Daniel Richard, Divya Venkatasubramanian, Rosanne M Raftery, Pushpanathan Muthuirulan, Zun Liu, Terence D Capellini, April M Craft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b27b5bb96683aa2a1b3ca15055e636
https://doi.org/10.7554/elife.79925.sa2
https://doi.org/10.7554/elife.79925.sa2
Autor:
David P. Walsh, Rosanne M. Raftery, Gang Chen, Fergal J. O'Brien, Andreas Heise, Robert Murphy, Sally-Ann Cryan
Publikováno v:
Biomaterials Science. 9:4984-4999
Increasingly, tissue engineering strategies such as the use of biomaterial scaffolds augmented with specific biological cues are being investigated to accelerate the regenerative process. For example, significant clinical challenges still exist in ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e9de387a5aec0d8d471c95aa72009f
https://doi.org/10.1039/d1bm00094b
https://doi.org/10.1039/d1bm00094b
Autor:
Rosanne M. Raftery, Gang Chen, Fergal J. O'Brien, Andreas Heise, Sally-Ann Cryan, David P. Walsh
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 13:1843-1853
The healing of large, critically sized bone defects remains an unmet clinical need in modern orthopaedic medicine. The tissue engineering field is increasingly using biomaterial scaffolds as 3D templates to guide the regenerative process, which can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7987e3c7ada39c10a68bb60fe52163
https://doi.org/10.1002/term.2934
https://doi.org/10.1002/term.2934
Autor:
Sally-Ann Cryan, Andreas Heise, David P. Walsh, Irene Mencía Castaño, Rosanne M. Raftery, Brenton Cavanagh, Fergal J. O'Brien, Robert Murphy
Publikováno v:
Journal of Controlled Release. 304:191-203
It is increasingly being recognised within the field of tissue engineering that the regenerative capacity of biomaterial scaffolds can be augmented via the incorporation of gene therapeutics. However, the field still lacks a biocompatible gene delive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a047947ebb8011a9c438597ec9f42bd
https://doi.org/10.1016/j.jconrel.2019.05.009
https://doi.org/10.1016/j.jconrel.2019.05.009
Autor:
Eamon J. Sheehy, Isabel Amado, Arlyng G. Gonzalez Vazquez, Gregory J. Miller, Kai Cortright, Rosanne M. Raftery, Gang Chen, Fergal J. O'Brien
Publikováno v:
Journal of Controlled Release
Leveraging the differential response of genes to mechanical loading may allow for the identification of novel therapeutics and we have recently established placental growth factor (PGF) as a mechanically augmented gene which promotes angiogenesis at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225b05a6b3553d7b79a67a737912c6e8
https://pubmed.ncbi.nlm.nih.gov/33811984
https://pubmed.ncbi.nlm.nih.gov/33811984
Autor:
Helena R. Moreira, Rosanne M. Raftery, Lucília P. da Silva, Mariana T. Cerqueira, Rui L. Reis, Alexandra P. Marques, Fergal J. O'Brien
Publikováno v:
Biomaterials science. 9(6)
Vascularization is still one of the major challenges in tissue engineering. In the context of tissue regeneration, the formation of capillary-like structures is often triggered by the addition of growth factors which are associated with high cost, bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2328a39ab941064a88043952fb3099b5
https://pubmed.ncbi.nlm.nih.gov/33514964
https://pubmed.ncbi.nlm.nih.gov/33514964
Publikováno v:
Advanced Healthcare Materials
Current treatments for articular cartilage defects relieve symptoms but often only delay cartilage degeneration. Mesenchymal stem cells (MSCs) have shown chondrogenic potential but tend to undergo endochondral ossification when implanted in vivo. Har
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edb335d4577469ca512ac4983aa92c9
Autor:
Irene Mencía, Castaño, Rosanne M, Raftery, Gang, Chen, Brenton, Cavanagh, Brian, Quinn, Garry P, Duffy, Fergal J, O'Brien, Caroline M, Curtin
Publikováno v:
Acta biomaterialia. 109
microRNAs offer vast therapeutic potential for multiple disciplines. From a bone perspective, inhibition of miR-133a may offer potential to enhance Runx2 activity and increase bone repair. This study aims to assess the therapeutic capability of antag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf6be6f7a146081945b69c89708ff3c5
https://pubmed.ncbi.nlm.nih.gov/32251781
https://pubmed.ncbi.nlm.nih.gov/32251781