Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Rosanne, Varkevisser"'
1
Akademický článek
Severe Bradycardia Increases the Incidence and Severity of Torsade de Pointes Arrhythmias by Augmenting Preexistent Spatial Dispersion of Repolarization in the CAVB Dog Model
Autor: Valerie Y. H. van Weperen, Albert Dunnink, Alexandre Bossu, Jet D. M. Beekman, Veronique M. F. Meijborg, Jacques M. T. de Bakker, Ruben Coronel, Rosanne Varkevisser, Marcel A. G. van der Heyden, Marc A. Vos
Publikováno v: Frontiers in Physiology, Vol 12 (2021)
IntroductionTorsade de pointes arrhythmias (TdP) in the chronic atrioventricular block (CAVB) dog model result from proarrhythmic factors, which trigger TdP and/or reinforce the arrhythmic substrate. This study investigated electrophysiological and a
Externí odkaz: https://doaj.org/article/bdacac999a3a459cabb1649d2d8663b1
Zobrazit plný text záznamu
2
Severe Bradycardia Increases the Incidence and Severity of Torsade de Pointes Arrhythmias by Augmenting Preexistent Spatial Dispersion of Repolarization in the CAVB Dog Model
Autor: Marcel A.G. van der Heyden, Valerie Y. H. van Weperen, Veronique M.F. Meijborg, J. Beekman, Alexandre Bossu, Jacques M.T. de Bakker, Rosanne Varkevisser, Albert Dunnink, Ruben Coronel, Marc A. Vos
Publikováno v: Frontiers in Physiology
Frontiers in physiology, 12:642083. Frontiers Media S.A.
Frontiers in Physiology, Vol 12 (2021)
IntroductionTorsade de pointes arrhythmias (TdP) in the chronic atrioventricular block (CAVB) dog model result from proarrhythmic factors, which trigger TdP and/or reinforce the arrhythmic substrate. This study investigated electrophysiological and a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907ecb97b0255aafa0cc09c3108eab18
https://doi.org/10.3389/fphys.2021.642083
Zobrazit plný text záznamu
4
Beat-to-beat variations in activation-recovery interval derived from the right ventricular electrogram can monitor arrhythmic risk under anesthetic and awake conditions in the canine chronic atrioventricular block model
Autor: David J. Sprenkeler, Alexandre Bossu, Alfonso Aranda Hernández, Sofieke C. Wijers, Marc A. Vos, Albert Dunnink, Jet D.M. Beekman, Rosanne Varkevisser, Mathias Meine
Publikováno v: Heart Rhythm, 15(3), 442. Elsevier
Background In the chronic atrioventricular block (CAVB) dog model, beat-to-beat variation of repolarization in the left ventricle (LV) quantified as short-term variability of the left monophasic action potential duration (STV LVMAPD ) increases abrup
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e357151c5abb41518544f68d167e406
https://doi.org/10.1016/j.hrthm.2017.11.011
Zobrazit plný text záznamu
5
The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models
Autor: Sander Verheule, Sihyung Yang, Yuan Ji, Rosanne Varkevisser, Alexandre Bossu, Dobromir Dobrev, Niels Voigt, Dragan Opacic, Marc A. Vos, Michael Zhuo Wang, Marion Kuiper, Jet D.M. Beekman, Marcel A.G. van der Heyden, Azinwi Phina Khan
Publikováno v: British Journal of Pharmacology. 174:2576-2590
Background and Purpose Inward rectifier current (IK1) density increases in atrial fibrillation (AF), shortening effective refractory period and thus promotes atrial reentry. Pentamidine-Analogue 6 (PA-6) is a selective and potent IK1 inhibitor. We te
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b49c612cd443301f93886d669a3f5d6b
https://doi.org/10.1111/bph.13869
Zobrazit plný text záznamu
6
Electrophysiological measurements that can explain and guide temporary accelerated pacing to avert (re)occurrence of torsade de pointes arrhythmias in the canine chronic atrioventricular block model
Autor: Albert Dunnink, Sofieke C. Wijers, Rosanne Varkevisser, Alexandre Bossu, Alfonso Aranda Hernández, Mathias Meine, Jet D.M. Beekman, Marc A. Vos
Publikováno v: Heart Rhythm, 14(5), 749. Elsevier
Background Pacing at higher rates is known to suppress torsade de pointes (TdP) arrhythmias. Nevertheless, exact application and mechanism need further clarification. In the anesthetized canine chronic atrioventricular block model, ventricular remode
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214e5c6d3f1a9f9c9eba67fb56312890
https://doi.org/10.1016/j.hrthm.2017.02.007
Zobrazit plný text záznamu
7
Short-term Variability of Repolarization Is Superior to Other Repolarization Parameters in the Evaluation of Diverse Antiarrhythmic Interventions in the Chronic Atrioventricular Block Dog
Autor: Rosanne Varkevisser, Marien J C Houtman, Henriette D.M. Beekman, Marc A. Vos, Alexandre Bossu, Marcel A.G. van der Heyden
Publikováno v: Journal of Cardiovascular Pharmacology
Journal of Cardiovascular Pharmacology, 69(6), 398. Lippincott Williams and Wilkins
Supplemental Digital Content is Available in the Text.
Short-term variability (STV), to quantify beat-to-beat variability of repolarization, is a surrogate parameter that reliably identifies proarrhythmic risk in preclinical models. Examples inc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add9eccaf2a946be03cab2a7a60dea14
http://europepmc.org/articles/PMC5464753
Zobrazit plný text záznamu
8
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are I
Autor: Igor, Baburin, Rosanne, Varkevisser, Anja, Schramm, Priyanka, Saxena, Stanislav, Beyl, Phillip, Szkokan, Tobias, Linder, Anna, Stary-Weinzinger, Marcel A G, van der Heyden, Marien, Houtman, Hiroki, Takanari, Malin, Jonsson, Jet H D, Beekman, Matthias, Hamburger, Marc A, Vos, Steffen, Hering
Publikováno v: Pharmacological research. 131
Evodiae fructus is a widely used herbal drug in traditional Chinese medicine. Evodia extract was found to inhibit hERG channels. The aim of the current study was to identify hERG inhibitors in Evodia extract and to investigate their potential proarrh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3a0e30d8137616ab18c26a4831a1c5f
https://pubmed.ncbi.nlm.nih.gov/29477480
Zobrazit plný text záznamu
9
AV-Block and Conduction Slowing Prevail Over TdP Arrhythmias in the Methoxamine-Sensitized Pro-Arrhythmic Rabbit Model
Autor: Ralph G. Tieland, Marc A. Vos, Jet D.M. Beekman, Marcel A.G. van der Heyden, Rosanne Varkevisser
Publikováno v: Journal of Cardiovascular Electrophysiology. 26:82-89
INTRODUCTION: The methoxamine-sensitized rabbit model is widely used to screen drugs for proarrhythmic properties, especially repolarization-dependent TdP arrhythmias. With the change of anesthesia and/or sensitizing agent, conduction disturbances ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef768e729dfe9ae50e74658c0bc79566
https://doi.org/10.1111/jce.12533
Zobrazit plný text záznamu
10
Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue
Autor: Adriaan P. IJzerman, M. Houtman, M A Vos, Anna Stary-Weinzinger, H D M Beekman, Rosanne Varkevisser, Tobias Linder, M. A. G. van der Heyden, K. C. G. de Git, Richard R. Tidwell
Publikováno v: British Journal of Pharmacology
Background and Purpose Drug interference with normal hERG protein trafficking substantially reduces the channel density in the plasma membrane and thereby poses an arrhythmic threat. The chemical substructures important for hERG trafficking inhibitio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07534ea8387e463b20c1a1d6f1a8326b
https://doi.org/10.1111/bph.12208
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje