Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rosanna Hok"'
Publikováno v:
Cancer Research. 81:385-385
Background: IRAK4, a serine/threonine kinase, was identified as a therapeutic target in hematological malignancies. IRAK4-mediated activation of NF-kappaB could play an important role in NF-kappaB-regulated survival and chemoresistance of cancer cell
Autor:
Christine Pak, Dhishant Asarpota, Aditya Khedkar, Abishy Pandita, Ashley Ayers, Lauren Miller, Jingzhi Zhu, Shweta Kitchloo, Melissa Chua Ming Jie, Caitlin Lawlor, Fatema Abdurrob, Grace Thole, Sarah Heerboth, Majed Abbas, Jacob Bishop, Caryn Navarro, Anar Alshanbayeva, Janani Ramachandran, Mariam Maloyan, Alexis Aparicio, Yasmina Samaha, Neil A. Patel, Martine Tremblay, Nikhil Dhar, Alexa Diedrich, Isabel Park, Theresa Christie, Rosanna Hok, Marinaliz Reynoso, Shannon Linderman, Qianjing He, Brian Leonard, Linge Xia, Jason Turnbill, A. Aziz, Talal Almojel, Thomas D. Gilmore, Ajith Thomas, Chelsea L. Fortin, Oliver Chung
Publikováno v:
BIOS. 86:165-175
NF-κB is an evolutionarily conserved eukaryotic transcription factor that plays a role in many important developmental and immune-related processes by activating target gene expression. The goal of these experiments was to define the sequences requi