Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rosanna Foderà"'
Autor:
Franco Zunino, Claudio Cavazza, Paolo Carminati, Daniela Passeri, Augusto Orlandi, Valentina Zuco, Paola Perego, Monica Tortoreto, Giovanna Petrangolini, Massimo Zucchetti, Maurizio D'Incalci, Marcella Barbarino, Rosanna Foderà, Mario Berardino Guglielmi, Ferdinando Maria Milazzo, Loredana Vesci, Claudio Pisano
Supplementary Figures S1-S2, Supplementary Materials and Methods, and Supplementary Tables S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcfa0370cc6132cda6f4246b52792b6
https://doi.org/10.1158/1078-0432.22442519
https://doi.org/10.1158/1078-0432.22442519
Autor:
Franco Zunino, Claudio Cavazza, Paolo Carminati, Daniela Passeri, Augusto Orlandi, Valentina Zuco, Paola Perego, Monica Tortoreto, Giovanna Petrangolini, Massimo Zucchetti, Maurizio D'Incalci, Marcella Barbarino, Rosanna Foderà, Mario Berardino Guglielmi, Ferdinando Maria Milazzo, Loredana Vesci, Claudio Pisano
Purpose: Acetyl-l-carnitine (ALC) plays a relevant role in energy metabolism and stress response because of its function in the complex metabolic system regulating the acetyl-CoA levels that provide a source of acetyl groups for metabolic and acetyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491ac695a485ceb3b81abb9e02d9f54d
https://doi.org/10.1158/1078-0432.c.6519233.v1
https://doi.org/10.1158/1078-0432.c.6519233.v1
Autor:
Alma Dal Pozzo, Claudio Pisano, Concetta Aulicino, Rosanna Foderà, Alberto Bargiotti, Minghong Ni, Federica Bucci, Massimo Castorina, Giuseppe Giannini, Emiliano Esposito, Sabrina Dallavalle, Loredana Vesci, Loana Musso, Sergio Penco
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:64-72
Five RGD peptide-camptothecin (CPT) conjugates were designed and synthesized with the purpose to improve the therapeutic index of this antitumoral drug family. New RGD cyclopeptides were selected on the basis of their high affinity to alpha(v) integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cec949374033eeb85ec2b35f3e1337
https://doi.org/10.1016/j.bmc.2009.11.019
https://doi.org/10.1016/j.bmc.2009.11.019
Autor:
Tiziana Brunetti, Claudio Pisano, Federica Bucci, Gianfranco Battistuzzi, Gianandrea Quattrociocchi, Rosanna Foderà, Mario B. Guglielmi, Raffaella Nannei, Lucio Merlini, Loredana Vesci, Maria Grazia Cima, Giuseppe Giannini, Domenico Alloatti, Raffaella Cincinelli, Walter Cabri, Sabrina Dallavalle
Adarotene belongs to the so-called class of atypical retinoids. The presence of the phenolic hydroxyl group on Adarotene structure allows a rapid O-glucuronidation as a major mechanism of elimination of the drug, favoring a fast excretion of its gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb170a3c854629de932bd0269c59ab72
http://hdl.handle.net/11585/756784
http://hdl.handle.net/11585/756784
Autor:
Maria Luisa Cervoni, Tiziana Brunetti, Walter Cabri, Mario B. Guglielmi, Giuseppina Grisolia, Loredana Vesci, Giuseppina Barbato, Rosanna Foderà, Ferdinando Maria Milazzo, Andrea Ciacci, Stefania Mangiola, Claudio Pisano, Massimo Castorina, Grazia Gallo, Giuseppe Giannini, Riccardo Rondanin, Paolo Marchetti, Daniele Simoni, Riccardo Baruchello, Marcella Barbarino, Domenico Alloatti
Publikováno v:
Journal of medicinal chemistry. 54(24)
A structural investigation on the isoxazole scaffold led to the discovery of 3,4-isoxazolediamide compounds endowed with potent Hsp90 inhibitory properties. We have found that compounds possessing a nitrogen atom directly attached to the C-4 heterocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071a2ef8e6366a930539f362c5d9fa98
https://pubmed.ncbi.nlm.nih.gov/22066525
https://pubmed.ncbi.nlm.nih.gov/22066525
Autor:
Monica Tortoreto, Loredana Vesci, Paolo Carminati, Daniela Passeri, Claudio Pisano, Marcella Barbarino, Franco Zunino, Paola Perego, Valentina Zuco, Ferdinando Maria Milazzo, Claudio Cavazza, Augusto Orlandi, Maurizio D'Incalci, Rosanna Foderà, Massimo Zucchetti, Giovanna Petrangolini, Mario B. Guglielmi
Purpose: Acetyl-l-carnitine (ALC) plays a relevant role in energy metabolism and stress response because of its function in the complex metabolic system regulating the acetyl-CoA levels that provide a source of acetyl groups for metabolic and acetyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b977e3175eb7356eef83aa31df57e2bc
http://hdl.handle.net/11365/1168592
http://hdl.handle.net/11365/1168592
Autor:
Claudio Pisano, Michelandrea De Cesare, Sabrina Dallavalle, Graziella Pratesi, Rosanna Foderà, Augusto Orlandi, Fabiana Fosca Ferrara, Loredana Vesci, Mario B. Guglielmi, Valentina Zuco, Paolo Carminati, Lucio Merlini, Gabriella Morini, Franco Zunino, Giovanni Luca Beretta, Sergio Penco
ST1968 is a novel hydrophilic camptothecin (CPT) derivative of the 7-oxyiminomethyl series. Because ST1968 retained ability to form remarkably stable cleavable complexes, this study was done to investigate its preclinical profile of antitumor activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58a32bb86689b514c105e42c04c8c14
http://hdl.handle.net/2108/43742
http://hdl.handle.net/2108/43742
Autor:
Loredana Vesci, Concetta Aulicino, Rosanna Foderà, Claudio Pisano, Michelandrea De Cesare, Federica Bucci, Franco Zunino, Valentina Benedetti, Sergio Penco, Paolo Carminati, Valentina Zuco
Publikováno v:
European journal of cancer (Oxford, England : 1990). 44(9)
ST1968, a novel hydrophilic camptothecin analogue of the 7-oxyiminomethyl series, is characterised by the formation of stable DNA-topoisomerase I cleavable complex and by a promising profile of antitumour activity. The present study was designed to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4c2571d391c7e7063fda1b9ae154c1
https://pubmed.ncbi.nlm.nih.gov/18445521
https://pubmed.ncbi.nlm.nih.gov/18445521
Autor:
Rosanna Supino, G Pratesi, C. Pisano, Rosanna Foderà, C. Rossi, M. De Cesare, Franco Zunino, Valentina Zuco, Fabiana Fosca Ferrara, Loredana Vesci
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 18(9)
Background: The novel adamantyl retinoid ST1926 is a potent inducer of apoptosis in ovarian carcinoma cells. Since the pro-apoptotic effect is associated with activation of p53, in this study we have investigated the efficacy of combination of ST1926
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d7a6826ed169601f8cb53975177001
https://pubmed.ncbi.nlm.nih.gov/17698835
https://pubmed.ncbi.nlm.nih.gov/17698835
Autor:
Franco Zunino, Claudio Pisano, Rosanna Foderà, Loredana Vesci, Ferdinando Maria Milazzo, Mario B. Guglielmi, Marcella Barbarino, Valentina Zuco
Publikováno v:
Cancer Research. 71:2623-2623
The novel hydroxamic acid-based compound ST3595, was identified within an in vitro screening for its inhibitory activity on histone deacetylase's (HDAC's) (Pisano C. et al., Clin Cancer Res 2010, 16 (15): 3944-53; Dalla Valle S et al., Eur J Med Chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c790a9895abf0b14b18b7ef94148b7
https://doi.org/10.1158/1538-7445.am2011-2623
https://doi.org/10.1158/1538-7445.am2011-2623